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View Structure Prediction Details

Protein: repo-PA
Organism: Drosophila melanogaster
Length: 612 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for repo-PA.

Description E-value Query
Range
Subject
Range
gi|3511287, gi|7... - pir||T31670 DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain - Mastigamoeba invertens (frag...
146.0 [0..343] [611..1418]

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Predicted Domain #1
Region A:
Residues: [1-74]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHDSFDDPI FGEFGGGPLN PLGAKPLMPT TTAMHPVMLG SVHELCSQQQ QQQQQQRLPD  60
   61 CNTILPNGGG GGAG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.15
Match: 1odhA
Description: Mgcm1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [75-285]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGGAGGSPNY VTKLDFVNKM GCYSPSQKYE YISAPQKLVE QQQQQQHHHQ HHQHYTATPP  60
   61 PSHNGILLHK QSSQQQQQQQ QQLVGILDYH PLNGKLDYSS SPKDQYEPQQ LQHLYGGSPH 120
  121 HLDHLDHGSD GLLQDSSPVM INGGSAGGKL KKPDEMCSQL EAGGAGVTPP SSSSTVVNGT 180
  181 TNGTGNANSS SSAGVGIQGA AGTAGGVAAP A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [286-367]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKKDGSSSKK KGDPNGIKKK KTRTTFTAYQ LEELERAFER APYPDVFARE ELAIKLNLSE  60
   61 SRVQVWFQNR RAKWRKHEPP RK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.154902
Match: 1fjlA
Description: Paired protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.334577365229545 bayes_pls_golite062009
transcription regulator activity 0.0696342306231097 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [368-612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGYIKTSTPP TATLNPGTLA PPFTSYPQTT TVTPPGSMDS WTSYQTPYEL TPQFSLLSPA  60
   61 ASPYGTYSGQ YGAYVHESQL FPMRHYEYGS PTRMEMGATT GSVAGNGDES VANGGSYQTA 120
  121 ELQTAQQQQL ADGTLVTVHA HQQQQQQQQQ LNGKYLSAEE AKYVHLQCHQ SGGGLELSPG 180
  181 ASCHLVEAQG QHYVTTATGG AASAGGTSSD DNDSGGMQTV IKSEEVSQQQ QQQQGQSYVL 240
  241 PPFLH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle