Protein Overview: Cctgamma-PD, Cct...

General Information:
Name(s) found:	Cctgamma-PD / FBpp0291566 [FlyBase] Cctgamma-PC / FBpp0291565 [FlyBase] Cctgamma-PB / FBpp0082788 [FlyBase] Cctgamma-PA / FBpp0082787 [FlyBase]
Description(s) found: Found 48 descriptions. SHOW ALL	The gene CctĂ?Ă?Âł is referred to in FlyBase by the symbol Dmel\CctĂ?Ă?Âł (CG8977, FBgn0015019). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12473311..12475700. It has the cytological map location 89D6. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled; unfolded protein binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization. 4 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene CctĂ?Ă?Âł is referred to in FlyBase by the symbol Dmel\CctĂ?Ă?Âł (CG8977, FBgn0015019). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12473311..12475700. It has the cytological map location 89D6. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled; unfolded protein binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization. 4 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene CctĂ?Ă?Âł is referred to in FlyBase by the symbol Dmel\CctĂ?Ă?Âł (CG8977, FBgn0015019). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12473311..12475700. It has the cytological map location 89D6. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled; unfolded protein binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization. 4 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene CctĂ?Ă?Âł is referred to in FlyBase by the symbol Dmel\CctĂ?Ă?Âł (CG8977, FBgn0015019). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12473311..12475700. It has the cytological map location 89D6. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled; unfolded protein binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization. 4 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	544 amino acids
Gene Ontology:
Cellular Component:	chaperonin-containing T-complex [ISS] cytoplasm [NAS]
Biological Process:	mitotic spindle organization [IMP] protein folding [ISS][NAS]
Molecular Function:	ATP binding [IEA] unfolded protein binding [ISS] ATPase activity, coupled [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGGQQPILV LSQNTKRESG RKVQLENIQA GKAIADVIRT CLGPQAMLKM LMDPMGGIVM  60
   61 TNDGNAILRE ITVQHPAAKS MIEIARTQDE EVGDGTTSVI VLAGEMLAAA EPFLQQQIHP 120
  121 TVIIRAYREA LEDIVGHLQS QLSIQLDVKD KAKMADVVKA CVGTKFIGKW SDLAVKIALD 180
  181 AVETVTLSEN GRLEVDIKRY AKVEKIPGGA IEESCVLKGV MINKDVTHPK MRRLIENPRI 240
  241 VLLDCSLEYK KGESQTNVEI IGEQDFTRML QIEEEFVQRI CADIIAVKPD LVFTEKGVSD 300
  301 LAQHYLLKAG ITAIRRLRKT DNLRIARACG ATIVNRTEEL TEKDVGTGAG LFEVKKIGDE 360
  361 YFTFVTECKE PKACTILLRG ASKDILNETE RNLQDALHVA RNLVLEPRLV AGGGAVEMAA 420
  421 SQLLTRKQVK GPYTAVAHAL EIIPRTLAQN CGANTIRALT ALRAKHASHT GDGVCAWGID 480
  481 GESGEIVDMN VKNIWEPLAV KLQTYKTAVE TAILLLRIDD IVSGSKKRGG NEPTNPAAMA 540
  541 QGQE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

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Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
unfolded protein binding	7.60116801069598	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	3.6934849790316	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	3.40373598585301	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	3.28982639907979	bayes_pls_golite062009
binding	2.07154556649829	bayes_pls_golite062009
nucleic acid binding	1.67284737458957	bayes_pls_golite062009
DNA binding	1.60256620441721	bayes_pls_golite062009
transporter activity	1.27879339110564	bayes_pls_golite062009
transmembrane transporter activity	1.08697283907212	bayes_pls_golite062009
chaperone binding	0.91200031047441	bayes_pls_golite062009
substrate-specific transporter activity	0.828920415160435	bayes_pls_golite062009
ATPase activity, coupled	0.787685249362834	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.75018875403424	bayes_pls_golite062009
pyrophosphatase activity	0.69634667457441	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.682843768728088	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.680378643689288	bayes_pls_golite062009
protein binding	0.634982583867058	bayes_pls_golite062009
ATPase activity	0.584574936611857	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.573106450426516	bayes_pls_golite062009
catalytic activity	0.424959044318554	bayes_pls_golite062009
ion transmembrane transporter activity	0.280310103153739	bayes_pls_golite062009
active transmembrane transporter activity	0.275534581026027	bayes_pls_golite062009
hydrogen-exporting ATPase activity, phosphorylative mechanism	0.26275673855778	bayes_pls_golite062009
primary active transmembrane transporter activity	0.252704226951294	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.243984617084631	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.205808843369749	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.202279803135899	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.20198255686005	bayes_pls_golite062009
transferase activity	0.18639662517366	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.16424934648837	bayes_pls_golite062009
kinase activity	0.0871496920547826	bayes_pls_golite062009
cation transmembrane transporter activity	0.0778814959589007	bayes_pls_golite062009
hydrolase activity	0.0491351110520448	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..544]	PSI-BLAST	136.0	Crystal structure of the chaperonin from Thermococcus strain KS-1 (nucleotide-free form of single mutant)

Protein Overview: Cctgamma-PD, Cct...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: