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Protein Overview: Nsf2-PA, FBpp031...

General Information:
Name(s) found: FBpp0311095 [FlyBase]
FBpp0311094 [FlyBase]
Nsf2-PA / FBpp0082346 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • type=protein; loc=3R:complement(9660402..9661259,9661499..9662464,9663100..9663424,9663525..9663634); ID=FBpp0311095; name=Nsf2-PC; parent=FBgn0266464,FBtr0344767; dbxref=FlyBase:FBpp0311095,FlyBase_Annotation_IDs:CG33101-PC; MD5=748209adb1189ce70192323504112ab5; length=752; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3R:complement(9660402..9661259,9661499..9662464,9663100..9663424,9663525..9663634); ID=FBpp0311094; name=Nsf2-PB; parent=FBgn0266464,FBtr0344766; dbxref=FlyBase:FBpp0311094,FlyBase_Annotation_IDs:CG33101-PB; MD5=748209adb1189ce70192323504112ab5; length=752; release=r5.56; species=Dmel; [FlyBase]
  • The gene NEM-sensitive fusion protein 2 is referred to in FlyBase by the symbol Dmel\Nsf2 (CG33101, FBgn0013998). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9660195..9663708. It has the cytological map location 87F15. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleoside-triphosphatase activity; ATP binding. There is experimental evidence that it is involved in the biological process</span>: neuromuscular synaptic transmission; regulation of synaptic growth at neuromuscular junction. 15 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye; larval neuromuscular junction; synaptic vesicle. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 752 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISS][NAS]
    Biological Process: ER to Golgi vesicle-mediated transport [ISS][NAS]
    synaptic vesicle priming [NAS]
    vesicle-mediated transport [NAS]
    neuromuscular synaptic transmission [IMP]
    regulation of synaptic growth at neuromuscular junction [IMP]
    intra-Golgi vesicle-mediated transport [NAS]
    neurotransmitter secretion [NAS]
    Molecular Function: ATP binding [IEA]
    nucleoside-triphosphatase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIEKAHRMR AIKCPTDELS LTNKAIVNVS DFTEEVKYVD ISPGPGLHYI FALEKISGPE  60
   61 LPLGHVGFSL VQRKWATLSI NQEIDVRPYR FDASADIITL VSFETDFLQK KTTTQEPYDS 120
  121 DEMAKEFLMQ FAGMPLTVGQ TLVFQFKDKK FLGLAVKTLE AVDPRTVGDS LPKTRNVRFG 180
  181 RILGNTVVQF EKAENSVLNL QGRSKGKIVR QSIINPDWDF GKMGIGGLDK EFNAIFRRAF 240
  241 ASRVFPPELV EQLGIKHVKG ILLYGPPGTG KTLMARQIGT MLNAREPKIV NGPQILDKYV 300
  301 GESEANIRRL FAEAEEEEKR LGPNSGLHII IFDEIDAICK ARGSVAGNSG VHDTVVNQLL 360
  361 AKIDGVEQLN NILVIGMTNR RDMIDEALLR PGRLEVQMEI SLPNEQGRVQ ILNIHTKRMR 420
  421 DFNKIASDVD NNEIAAKTKN FSGAELEGLV RAAQSTAMNR LIKADSKVHV DPEAMEKLRV 480
  481 TRADFLHALD NDIKPAFGAA QEMLENLLAR GIINWGPPVT ELLEDGMLSV QQAKATESSG 540
  541 LVSVLIEGAP NSGKSALAAN LAQLSDFPFV KVCSPEDMVG FTESAKCLHI RKIFDDAYRS 600
  601 TLSCIVVDNV ERLLDYGPIG PRYSNLTLQA LLVLLKKQPP KGRKLLILCT SSRRDVLEEM 660
  661 EMLSAFTSVL HVSNLSTPEN VLAVLDDSDL FSPEELQSIA RKMAGKRLCI GIKKLLALID 720
  721 MIRQSEPHQR VIKFLSKMEE EGGLEMDRVQ GH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..752] PSI-BLAST 128.0 VCP/p97


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle