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Protein Overview: CG5641-PA

General Information:
Name(s) found: CG5641-PA / FBpp0082066 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG5641 (CG5641, FBgn0038046). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8253515..8255002. It has the cytological map location 87B10. Based on sequence similarity, it is predicted to have molecular function</span>: DNA binding; double-stranded RNA binding; protein binding; transcription regulator activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: positive regulation of transcription, DNA-dependent. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 396 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    nucleolus [ISS]
    Biological Process: immune response [IEA]
    positive regulation of transcription, DNA-dependent [ISS]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: ATP binding [IEA]
    DNA binding [ISS]
    protein binding [ISS]
    transcription regulator activity [ISS]
    double-stranded RNA binding [ISS]
    transferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRGALRGGR PMRGGIRPPF KKTFVPRHPF DLTLAEVFFP KVPSAGAVDD SALTAALLKR  60
   61 NQDLSPTPSE QTAIGNLVTK VQAVLDNLVV APGDLTTCQL EEVRQVGSFK KGTILTGNNV 120
  121 ADVVVILKTL PTKEAVDALA KKVEADLKAS MKTEVLTKGD QHTVQIHERG FDIANVHAKV 180
  181 RILIATLPQN LRKLEPEIHL DHKLMQSHLA AIRHTRWFEE NAHHSSIKVL IRILKDLTRR 240
  241 FDAFSPLSAW MLDLIAHLAI MNNPSRQALP INLAFRRVFQ LLSAGLFLPG SAGITDPTEP 300
  301 GHIRVHTAMT LEQQDVCCYT SQTLLRVLAH GGYKHILGLE GNTSVVREMS VWNGVCISPL 360
  361 TAVYEKPTDK KEGDLEEDID MIENENEEEG SDDGAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..396] FFAS03 4.21 Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleic acid binding
    		•  2.50521008579083 bayes_pls_golite062009
  • DNA binding
    		•  1.93756366394825 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.8818754043876 bayes_pls_golite062009
  • binding
    		•  1.53356592031109 bayes_pls_golite062009
  • protein binding
    		•  1.20472171285911 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.825883515331479 bayes_pls_golite062009
  • catalytic activity
    		•  0.718799603354138 bayes_pls_golite062009
  • transcription factor binding
    		•  0.254356559478393 bayes_pls_golite062009
  • transferase activity
    		•  0.245732860673913 bayes_pls_golite062009
  • RNA binding
    		•  0.0987316638685425 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.75

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle