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Protein Overview: Lk6-PB

General Information:
Name(s) found: Lk6-PB / FBpp0082009 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Lk6 is referred to in FlyBase by the symbol Dmel\Lk6 (CG17342, FBgn0017581). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7578506..7590179. It has the cytological map location 86E18. There is experimental evidence that it has the molecular function</span>: protein kinase activity; kinase activity. There is experimental evidence that it is involved in the biological process</span>: microtubule-based process; regulation of growth. 58 alleles are reported. The phenotypes of these alleles are annotated with: larva; adult; salivary gland; larval fat body; egg; second instar larva; wing. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1090 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDA]
    centrosome [IDA]
    cytoplasm [IDA]
    microtubule [IDA]
    Biological Process: regulation of translation [IEA]
    protein amino acid phosphorylation [IEA][NAS]
    regulation of growth [IMP]
    response to stress [IEA]
    microtubule-based process [IMP]
    Molecular Function: ATP binding [IEA]
    protein kinase activity [IDA]
    protein serine/threonine kinase activity [ISS][NAS]
    kinase activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDGQNELTR YSSEDVSGNE SSEAPNMTEV ERQAELNRHK EEMQKKRRKK RISSSLHSST  60
   61 FQELYKLTGE ILGEGAYASV QTCVNIYTDL EYAVKVIDKI PGHARARVFR EVETFHHCQG 120
  121 HLGILQLIEF FEDDEKFYLV FEKINGGPLL SRIQEHICFS EHEASQIIKE IASGLDFLHK 180
  181 KGIAHRDLKP ENILCVKTDS LCPIKICDFD LGSGIKFTTD ISSPAATPQL LTPVGSAEFM 240
  241 APEVVDLFVG EAHYYDKRCD LWSLGVIAYI LLCGYPPFSG NCGEDCGWNR GENCRTCQEL 300
  301 LFESIQEGHF SFPEAEWHDV SDEAKDLISN LLVKKASNRL SAEAVLNHPW IRMCEQEPPA 360
  361 SKHGRRHKAL QTPSNIRRNH QSAREISQFA ESAMAVKRVV LQHFSMRYDY MKERPNIYQP 420
  421 SQAYMDAYSD ENYNPKPPGH YTRNRSQRNP ASSLCGYGGR MSSMHGQRAN SRRSSRNASR 480
  481 NASAIYPNSG GFKTLNVHEE DDDDEGLEAF GHIDDDDEWS RSRREYQQQC ETLGEDRFRR 540
  541 QSGSEGDEVE DDEDGENEDY QHYKHYWREL DEEEGDDYLY EQQQRVDDKF GEEEFEDEPK 600
  601 EETQADNLKL SKAYVEQVGE TNVEKSKPQD DNGGYIREDL IMDNMDMKKN TQQSEFAKLT 660
  661 IMRNDAQTEE NKIMQQQDEE KKEEKQQDDV DGAKKQGPSS DISATTITDN NKLQTPVMTT 720
  721 THINNWQTGD AIEDDDVKLL DSISDLNEKL PEIYETANIV VNSAAVPAAS TPAASATRPP 780
  781 TDNPEEDDSN VTKPTTTAEG TTMQTTFGMS AEEEKPVALS HTAGHHSKTG RTVNFAPDAY 840
  841 QNDEDADIDE DDDYDDEENL HEHSKQQLPS NAYTRKQRQQ HQRYIVPRYQ LADQVPQRQH 900
  901 TENWRYRTHH SQEQQPTADY RKYRPPFSTG GGGGHHGNQQ RNYLGSFSHS GGAAGYKIAP 960
  961 MPPPMQPPPR HNSAGSSGSG SGSGGSPPSD EQSAIRNWRQ DCVYARSCGM NQGPEQQRHN1020
 1021 RSSGQRVQQQ PRIGSGRFAH LQAAQLMDEL PDMRIGLSPP SESVLLQRRL RQQQRANDLS1080
 1081 EYCEPATASG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..353] PSI-BLAST 69.30103 No description for 2hw6A was found.
    2 View Details [354..569] deduced N/A No confident structure predictions are available.
    3 View Details [570..949] PSI-BLAST 23.0 Heavy meromyosin subfragment
    4 View Details [950..1090] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle