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View Structure Prediction Details

Protein: Lk6-PB
Organism: Drosophila melanogaster
Length: 1090 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Lk6-PB.

Description E-value Query
Range
Subject
Range
Lk6-PA - The gene Lk6 is referred to in FlyBase by the symbol Dmel\Lk6 (CG17342, FBgn0017581). It is a protei...
508.0 [0..3] [1090..55]

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Predicted Domain #1
Region A:
Residues: [1-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDGQNELTR YSSEDVSGNE SSEAPNMTEV ERQAELNRHK EEMQKKRRKK RISSSLHSST  60
   61 FQELYKLTGE ILGEGAYASV QTCVNIYTDL EYAVKVIDKI PGHARARVFR EVETFHHCQG 120
  121 HLGILQLIEF FEDDEKFYLV FEKINGGPLL SRIQEHICFS EHEASQIIKE IASGLDFLHK 180
  181 KGIAHRDLKP ENILCVKTDS LCPIKICDFD LGSGIKFTTD ISSPAATPQL LTPVGSAEFM 240
  241 APEVVDLFVG EAHYYDKRCD LWSLGVIAYI LLCGYPPFSG NCGEDCGWNR GENCRTCQEL 300
  301 LFESIQEGHF SFPEAEWHDV SDEAKDLISN LLVKKASNRL SAEAVLNHPW IRM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.30103
Match: 2hw6A
Description: No description for 2hw6A was found.

Predicted Domain #2
Region A:
Residues: [354-569]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CEQEPPASKH GRRHKALQTP SNIRRNHQSA REISQFAESA MAVKRVVLQH FSMRYDYMKE  60
   61 RPNIYQPSQA YMDAYSDENY NPKPPGHYTR NRSQRNPASS LCGYGGRMSS MHGQRANSRR 120
  121 SSRNASRNAS AIYPNSGGFK TLNVHEEDDD DEGLEAFGHI DDDDEWSRSR REYQQQCETL 180
  181 GEDRFRRQSG SEGDEVEDDE DGENEDYQHY KHYWRE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [570-949]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDEEEGDDYL YEQQQRVDDK FGEEEFEDEP KEETQADNLK LSKAYVEQVG ETNVEKSKPQ  60
   61 DDNGGYIRED LIMDNMDMKK NTQQSEFAKL TIMRNDAQTE ENKIMQQQDE EKKEEKQQDD 120
  121 VDGAKKQGPS SDISATTITD NNKLQTPVMT TTHINNWQTG DAIEDDDVKL LDSISDLNEK 180
  181 LPEIYETANI VVNSAAVPAA STPAASATRP PTDNPEEDDS NVTKPTTTAE GTTMQTTFGM 240
  241 SAEEEKPVAL SHTAGHHSKT GRTVNFAPDA YQNDEDADID EDDDYDDEEN LHEHSKQQLP 300
  301 SNAYTRKQRQ QHQRYIVPRY QLADQVPQRQ HTENWRYRTH HSQEQQPTAD YRKYRPPFST 360
  361 GGGGGHHGNQ QRNYLGSFSH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [950-1090]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGGAAGYKIA PMPPPMQPPP RHNSAGSSGS GSGSGGSPPS DEQSAIRNWR QDCVYARSCG  60
   61 MNQGPEQQRH NRSSGQRVQQ QPRIGSGRFA HLQAAQLMDE LPDMRIGLSP PSESVLLQRR 120
  121 LRQQQRANDL SEYCEPATAS G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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