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Protein Overview: Lk6-PA

General Information:
Name(s) found: Lk6-PA / FBpp0082008 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene Lk6 is referred to in FlyBase by the symbol Dmel\Lk6 (CG17342, FBgn0017581). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7578506..7590179. It has the cytological map location 86E18. There is experimental evidence that it has the molecular function</span>: protein kinase activity; kinase activity. There is experimental evidence that it is involved in the biological process</span>: microtubule-based process; regulation of growth. 58 alleles are reported. The phenotypes of these alleles are annotated with: larva; adult; salivary gland; larval fat body; egg; second instar larva; wing. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1142 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDA]
    centrosome [IDA]
    cytoplasm [IDA]
    microtubule [IDA]
    Biological Process: regulation of translation [IEA]
    protein amino acid phosphorylation [IEA][NAS]
    regulation of growth [IMP]
    response to stress [IEA]
    microtubule-based process [IMP]
    Molecular Function: ATP binding [IEA]
    protein kinase activity [IDA]
    protein serine/threonine kinase activity [ISS][NAS]
    kinase activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEPKSGTAA SAAAAKASNN NNNNHPRGSG DSGIRSGSGI SCSNTDNSCS QSQSDGQNEL  60
   61 TRYSSEDVSG NESSEAPNMT EVERQAELNR HKEEMQKKRR KKRISSSLHS STFQELYKLT 120
  121 GEILGEGAYA SVQTCVNIYT DLEYAVKVID KIPGHARARV FREVETFHHC QGHLGILQLI 180
  181 EFFEDDEKFY LVFEKINGGP LLSRIQEHIC FSEHEASQII KEIASGLDFL HKKGIAHRDL 240
  241 KPENILCVKT DSLCPIKICD FDLGSGIKFT TDISSPAATP QLLTPVGSAE FMAPEVVDLF 300
  301 VGEAHYYDKR CDLWSLGVIA YILLCGYPPF SGNCGEDCGW NRGENCRTCQ ELLFESIQEG 360
  361 HFSFPEAEWH DVSDEAKDLI SNLLVKKASN RLSAEAVLNH PWIRMCEQEP PASKHGRRHK 420
  421 ALQTPSNIRR NHQSAREISQ FAESAMAVKR VVLQHFSMRY DYMKERPNIY QPSQAYMDAY 480
  481 SDENYNPKPP GHYTRNRSQR NPASSLCGYG GRMSSMHGQR ANSRRSSRNA SRNASAIYPN 540
  541 SGGFKTLNVH EEDDDDEGLE AFGHIDDDDE WSRSRREYQQ QCETLGEDRF RRQSGSEGDE 600
  601 VEDDEDGENE DYQHYKHYWR ELDEEEGDDY LYEQQQRVDD KFGEEEFEDE PKEETQADNL 660
  661 KLSKAYVEQV GETNVEKSKP QDDNGGYIRE DLIMDNMDMK KNTQQSEFAK LTIMRNDAQT 720
  721 EENKIMQQQD EEKKEEKQQD DVDGAKKQGP SSDISATTIT DNNKLQTPVM TTTHINNWQT 780
  781 GDAIEDDDVK LLDSISDLNE KLPEIYETAN IVVNSAAVPA ASTPAASATR PPTDNPEEDD 840
  841 SNVTKPTTTA EGTTMQTTFG MSAEEEKPVA LSHTAGHHSK TGRTVNFAPD AYQNDEDADI 900
  901 DEDDDYDDEE NLHEHSKQQL PSNAYTRKQR QQHQRYIVPR YQLADQVPQR QHTENWRYRT 960
  961 HHSQEQQPTA DYRKYRPPFS TGGGGGHHGN QQRNYLGSFS HSGGAAGYKI APMPPPMQPP1020
 1021 PRHNSAGSSG SGSGSGGSPP SDEQSAIRNW RQDCVYARSC GMNQGPEQQR HNRSSGQRVQ1080
 1081 QQPRIGSGRF AHLQAAQLMD ELPDMRIGLS PPSESVLLQR RLRQQQRAND LSEYCEPATA1140
 1141 SG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..102] deduced N/A No confident structure predictions are available.
    2 View Details [103..457] PSI-BLAST 68.09691 No description for 2hw6A was found.
    3 View Details [458..633] deduced N/A No confident structure predictions are available.
    4 View Details [634..1002] PSI-BLAST 21.0 Heavy meromyosin subfragment
    5 View Details [1003..1142] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.53

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle