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View Structure Prediction Details

Protein: Lk6-PA
Organism: Drosophila melanogaster
Length: 1142 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Lk6-PA.

Description E-value Query
Range
Subject
Range
gi|7511959, gi|1... - pir||T13824 LK6 protein kinase - fruit fly (Drosophila melanogaster), gi|1667486|gb|AAB18789.1| LK6 ...
551.0 [0..1] [1133..1]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEPKSGTAA SAAAAKASNN NNNNHPRGSG DSGIRSGSGI SCSNTDNSCS QSQSDGQNEL  60
   61 TRYSSEDVSG NESSEAPNMT EVERQAELNR HKEEMQKKRR KK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [103-457]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RISSSLHSST FQELYKLTGE ILGEGAYASV QTCVNIYTDL EYAVKVIDKI PGHARARVFR  60
   61 EVETFHHCQG HLGILQLIEF FEDDEKFYLV FEKINGGPLL SRIQEHICFS EHEASQIIKE 120
  121 IASGLDFLHK KGIAHRDLKP ENILCVKTDS LCPIKICDFD LGSGIKFTTD ISSPAATPQL 180
  181 LTPVGSAEFM APEVVDLFVG EAHYYDKRCD LWSLGVIAYI LLCGYPPFSG NCGEDCGWNR 240
  241 GENCRTCQEL LFESIQEGHF SFPEAEWHDV SDEAKDLISN LLVKKASNRL SAEAVLNHPW 300
  301 IRMCEQEPPA SKHGRRHKAL QTPSNIRRNH QSAREISQFA ESAMAVKRVV LQHFS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.09691
Match: 2hw6A
Description: No description for 2hw6A was found.

Predicted Domain #3
Region A:
Residues: [458-633]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRYDYMKERP NIYQPSQAYM DAYSDENYNP KPPGHYTRNR SQRNPASSLC GYGGRMSSMH  60
   61 GQRANSRRSS RNASRNASAI YPNSGGFKTL NVHEEDDDDE GLEAFGHIDD DDEWSRSRRE 120
  121 YQQQCETLGE DRFRRQSGSE GDEVEDDEDG ENEDYQHYKH YWRELDEEEG DDYLYE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [634-1002]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQQRVDDKFG EEEFEDEPKE ETQADNLKLS KAYVEQVGET NVEKSKPQDD NGGYIREDLI  60
   61 MDNMDMKKNT QQSEFAKLTI MRNDAQTEEN KIMQQQDEEK KEEKQQDDVD GAKKQGPSSD 120
  121 ISATTITDNN KLQTPVMTTT HINNWQTGDA IEDDDVKLLD SISDLNEKLP EIYETANIVV 180
  181 NSAAVPAAST PAASATRPPT DNPEEDDSNV TKPTTTAEGT TMQTTFGMSA EEEKPVALSH 240
  241 TAGHHSKTGR TVNFAPDAYQ NDEDADIDED DDYDDEENLH EHSKQQLPSN AYTRKQRQQH 300
  301 QRYIVPRYQL ADQVPQRQHT ENWRYRTHHS QEQQPTADYR KYRPPFSTGG GGGHHGNQQR 360
  361 NYLGSFSHS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [1003-1142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGAAGYKIAP MPPPMQPPPR HNSAGSSGSG SGSGGSPPSD EQSAIRNWRQ DCVYARSCGM  60
   61 NQGPEQQRHN RSSGQRVQQQ PRIGSGRFAH LQAAQLMDEL PDMRIGLSPP SESVLLQRRL 120
  121 RQQQRANDLS EYCEPATASG 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle