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Protein Overview: FBpp0308021

General Information:
Name(s) found: FBpp0308021 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • type=protein; loc=3R:complement(6188885..6189019,6189089..6189457,6189668..6189982,6190201..6190503,6190689..6191147,6191227..6191391,6191458..6191695,6191771..6191849,6197871..6198255,6198463..6198708); ID=FBpp0308021; name=Rfx-PJ; parent=FBgn0020379,FBtr0337107; dbxref=REFSEQ:NP_649999,GB_protein:AAF54526,FlyBase:FBpp0308021,FlyBase_Annotation_IDs:CG6312-PJ; MD5=f22d322f3b742cf6d3ebc8d514f2bdf0; length=897; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 897 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    Biological Process: nervous system development [IMP]
    regulation of transcription, DNA-dependent [IEA]
    regulation of transcription [TAS]
    dendrite morphogenesis [TAS]
    Molecular Function: DNA binding [IEA]
    RNA polymerase II transcription factor activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTRLAPQRQ FILSTRSAIV DATSPPEDSA EEQQQLTVEV ESATNGVITN STTSPPPHAE  60
   61 QFEFCTEDGV VVSATLEDVM TQVKLFPLLQ NCQLLQKKLV DEDDDSTGVG ATDADQLEVI 120
  121 SVVLPMDAED STSDAHLHGH VVNSSSDTMG TITTTEPNGT TVTHSIPIHS MADLAAIKDG 180
  181 VDLAQQVANG QVTVVQTTED DDGTPFITVT VSGQEQNYQV QYVDSELYHS NSSQTQMTYP 240
  241 FCPVGDYQGN GQTAYYSTTG QYGTTSSAGG SSNGAHSTTL PYLVPVEEGI LLNGSAHSLS 300
  301 QSQSQSHGRD SPHSLTEVAY IQEAQSTPQT PTSTTTTHSA SGGSLGTGGG GASPDSDQSA 360
  361 LGSSNKIASA TIKWLSRNYE TADGVSLPRS TLYNHYMQHC SEHKLEPVNA ASFGKLIRSV 420
  421 FSGLRTRRLG TRGNSKYHYY GIRIKPGSLL NSQAMDDKQM LAAGYGPSSD GTGGPGSGPM 480
  481 VSVTSSTAGQ LTGSNGLGGG HGQRHSNGTK KHTFKPETYE ACIQYIGDGT SALPSFPPIE 540
  541 LNHSFNSELT LEDVDTFRGL YREHCESFLD AVLNLEFNTV EFLLRDFWRA SDNNNLDECE 600
  601 EEKYLSKTKL YLLCHCAEVQ KFVREVDYQF YQNTVDVIIP DVLRSIPNAL TQAIRNFAKN 660
  661 LEIWLCESML GVPEQLAQIK TSAVSAFCQT LRRYTSLNHL AQAARAVLQN GAQISQMLSD 720
  721 LNRVDFHNVQ EQAAWVSQCA PAVVQRLESD FKAALQQQSS LEQWASWLQL VVESAMEEYN 780
  781 GKPTYARAAR QFLLKWSFYS SMIIRDLTLR SASSFGSFHL IRLLFDEYMF YLVEHKIAEA 840
  841 QDKTAIAVIC ERMKKDMDFE FECQFAYITS DTEHQTTPSS ASSGGDVGNE AKRLKQE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..160] MSA 2.190996 View MSA. No confident structure predictions are available.
    2 View Details [161..305] MSA 3.215987 View MSA. No confident structure predictions are available.
    3 View Details [306..358] deduced N/A No confident structure predictions are available.
    4 View Details [359..507] PSI-BLAST 23.221849 Class II MHC transcription factor RFX1
    5 View Details [508..611] deduced N/A No confident structure predictions are available.
    6 View Details [612..809] MSA 1.07992 View MSA. No confident structure predictions are available.
    7 View Details [810..897] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  5.55329976718261 bayes_pls_golite062009
  • DNA binding
    		•  5.08959163553491 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.69183445184264 bayes_pls_golite062009
  • transcription factor activity
    		•  4.33152142980289 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.48053910222825 bayes_pls_golite062009
  • transcription activator activity
    		•  2.37668609508629 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.22485867684613 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.70025468248325 bayes_pls_golite062009
  • transcription factor binding
    		•  0.85714789329232 bayes_pls_golite062009
  • protein binding
    		•  0.753698599635855 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.0856082199488197 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle