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View Structure Prediction Details

Protein: FBpp0308021
Organism: Drosophila melanogaster
Length: 897 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0308021.

Description E-value Query
Range
Subject
Range
gi|6580397 - gi|6580397|emb|CAB63452.1| RFX transcription factor [Drosophila melanogaster]
746.0 [0..1] [897..1]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTRLAPQRQ FILSTRSAIV DATSPPEDSA EEQQQLTVEV ESATNGVITN STTSPPPHAE  60
   61 QFEFCTEDGV VVSATLEDVM TQVKLFPLLQ NCQLLQKKLV DEDDDSTGVG ATDADQLEVI 120
  121 SVVLPMDAED STSDAHLHGH VVNSSSDTMG TITTTEPNGT 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [161-305]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVTHSIPIHS MADLAAIKDG VDLAQQVANG QVTVVQTTED DDGTPFITVT VSGQEQNYQV  60
   61 QYVDSELYHS NSSQTQMTYP FCPVGDYQGN GQTAYYSTTG QYGTTSSAGG SSNGAHSTTL 120
  121 PYLVPVEEGI LLNGSAHSLS QSQSQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [306-358]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHGRDSPHSL TEVAYIQEAQ STPQTPTSTT TTHSASGGSL GTGGGGASPD SDQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [359-507]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SALGSSNKIA SATIKWLSRN YETADGVSLP RSTLYNHYMQ HCSEHKLEPV NAASFGKLIR  60
   61 SVFSGLRTRR LGTRGNSKYH YYGIRIKPGS LLNSQAMDDK QMLAAGYGPS SDGTGGPGSG 120
  121 PMVSVTSSTA GQLTGSNGLG GGHGQRHSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.221849
Match: 1dp7P
Description: Class II MHC transcription factor RFX1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 5.08959163553491 bayes_pls_golite062009
nucleic acid binding 4.69183445184264 bayes_pls_golite062009
transcription factor activity 4.33152142980289 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
sequence-specific DNA binding 2.48053910222825 bayes_pls_golite062009
transcription activator activity 2.37668609508629 bayes_pls_golite062009
transcription repressor activity 2.22485867684613 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.70025468248325 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
protein binding 0.753698599635855 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.0856082199488197 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [508-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTKKHTFKPE TYEACIQYIG DGTSALPSFP PIELNHSFNS ELTLEDVDTF RGLYREHCES  60
   61 FLDAVLNLEF NTVEFLLRDF WRASDNNNLD ECEEEKYLSK TKLY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [612-809]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLCHCAEVQK FVREVDYQFY QNTVDVIIPD VLRSIPNALT QAIRNFAKNL EIWLCESMLG  60
   61 VPEQLAQIKT SAVSAFCQTL RRYTSLNHLA QAARAVLQNG AQISQMLSDL NRVDFHNVQE 120
  121 QAAWVSQCAP AVVQRLESDF KAALQQQSSL EQWASWLQLV VESAMEEYNG KPTYARAARQ 180
  181 FLLKWSFYSS MIIRDLTL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [810-897]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSASSFGSFH LIRLLFDEYM FYLVEHKIAE AQDKTAIAVI CERMKKDMDF EFECQFAYIT  60
   61 SDTEHQTTPS SASSGGDVGN EAKRLKQE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle