YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: CG3999-PA, FBpp0...

General Information:
Name(s) found: FBpp0307977 [FlyBase]
CG3999-PA / FBpp0081703 [FlyBase]
Description(s) found:
Found 27 descriptions.
SHOW ALL
  • type=protein; loc=3R:join(6077302..6077478,6077611..6077689,6077893..6078419,6078520..6079253,6079312..6080641,6080703..6080813); ID=FBpp0307977; name=CG3999-PB; parent=FBgn0037801,FBtr0337048; dbxref=REFSEQ:NP_001262456,GB_protein:AGB95838,FlyBase:FBpp0307977,FlyBase_Annotation_IDs:CG3999-PB; MD5=571c87fdc1c958b5cf623625d8447aef; length=985; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG3999 (CG3999, FBgn0037801). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6077240..6081002. It has the cytological map location 86A2. Based on sequence similarity, it is predicted to have molecular function</span>: glycine dehydrogenase (decarboxylating) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; glycine metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 985 amino acids

    Gene Ontology:
    Cellular Component: glycine cleavage complex [ISS]
    Biological Process: oxidation reduction [IEA]
    glycine metabolic process [IEA]
    Molecular Function: pyridoxal phosphate binding [IEA]
    glycine dehydrogenase (decarboxylating) activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRFLGRSSQ SLLLRCGHRY LATTPVEEVI FPTKSDFPSR HIGPRKTDVV AMLDTLGFKS  60
   61 LAELTEKAVP QSIQLKRELD LDKPLNEHEL IRRIRDISLK NQLWRSYIGM GYHNCHVPHT 120
  121 IIRNMFENPG WTTQYTPYQP EIAQGRLESL LNYQTLVTDL TGLDVANASL LDEGTAAAEA 180
  181 MCLATRHNKR KKLYLSNRVH PQTLSVVKTR TEALELEIVV GPIEQADLPS RELAGILLQY 240
  241 PDTYGDVKDF EDIAALAKKN GTLVVVATDL LSLTLLRPPA EFGADIAVGT SQRLGVPLGY 300
  301 GGPHAGFFAC KQSLVRLMPG RMIGVTRDMD GNDAYRLALQ TREQHIRRDK ATSNICTAQA 360
  361 LLANMSAMYA IYHGPEGLKA MANRIHHFTL TLQTGVLGAG HEVINKNFFD TLHIRLGGGQ 420
  421 SLEDLKERAE HKRINLRYLE DDTVGVALDE TVSVADVDDL LWVFKAEASV EHILARKDVL 480
  481 KNSIENSKFL RTSPYLQHPI FQSYHSESRM VRYMKKLENK DISLVHSMIP LGSCTMKLNS 540
  541 TTEMMPCSFR HFTDIHPFAP VEQAQGFHQM FKELEHDLCE ITGYDRISFQ PNSGAQGEYA 600
  601 GLRAIRSYHE HRNEGHRNIC LIPISAHGTN PASAQMAGMK VEPIRILSNG SIDMAHLRAK 660
  661 AEEHAHELSC LMITYPSTMG VFEETVADIC TLIHKHGGQV YLDGANMNAQ VGLCRPGDYG 720
  721 SDVSHLNLHK TFCIPHGGGG PGMGPIGVKA HLAPYLPGHP VVSPLSSEEH SFGVVSAAPF 780
  781 GSSAILPISW SYIKLMGSRG LKRATQVAIL NANYMSKRLE QHYKTLYKAP NSQLVAHEFI 840
  841 LDIRDLKKSA NIEAVDVAKR LMDYGFHAPT MSWPVAGTLM IEPTESEDKE ELDRFCDAMI 900
  901 SIREEIAEIE AGRMDKAVNP LKMSPHTQAQ VISDKWDRPY TREQAAFPAI FVKPDAKIWP 960
  961 TVGRIDDAYG DKHLVCTCPP ILPDL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..467] PSI-BLAST 74.522879 Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in apo form
    2 View Details [468..985] PSI-BLAST 72.221849 Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in apo form

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glycine dehydrogenase (decarboxylating) activity
    		•  8.00572280567771 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  8.00572280567771 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors
    		•  3.14486270422678 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • transferase activity
    		•  1.44093490824786 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.681623261233707 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  0.619695949258279 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.60304280865376 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  0.271623203801431 bayes_pls_golite062009
  • O-phospho-L-serine:2-oxoglutarate aminotransferase activity
    		•  0.234399054481664 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
    2
    Term Confidence Notes
  • glycine dehydrogenase (decarboxylating) activity
    		•  8.00572280567771 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  8.00572280567771 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors
    		•  3.14486270422678 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • transferase activity
    		•  1.44093490824786 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.681623261233707 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  0.619695949258279 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.60304280865376 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  0.271623203801431 bayes_pls_golite062009
  • O-phospho-L-serine:2-oxoglutarate aminotransferase activity
    		•  0.234399054481664 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle