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View Structure Prediction Details

Protein: CG3999-PA, FBpp0...
Organism: Drosophila melanogaster
Length: 985 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG3999-PA, FBpp0....

Description E-value Query
Range
Subject
Range
gi|89093021, gi|... - gi|89093021|ref|ZP_01165972.1| glycine dehydrogenase [Oceanospirillum sp. MED92], gi|89082671|gb|EAR...
873.0 [0..20] [984..1]

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Predicted Domain #1
Region A:
Residues: [1-467]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRFLGRSSQ SLLLRCGHRY LATTPVEEVI FPTKSDFPSR HIGPRKTDVV AMLDTLGFKS  60
   61 LAELTEKAVP QSIQLKRELD LDKPLNEHEL IRRIRDISLK NQLWRSYIGM GYHNCHVPHT 120
  121 IIRNMFENPG WTTQYTPYQP EIAQGRLESL LNYQTLVTDL TGLDVANASL LDEGTAAAEA 180
  181 MCLATRHNKR KKLYLSNRVH PQTLSVVKTR TEALELEIVV GPIEQADLPS RELAGILLQY 240
  241 PDTYGDVKDF EDIAALAKKN GTLVVVATDL LSLTLLRPPA EFGADIAVGT SQRLGVPLGY 300
  301 GGPHAGFFAC KQSLVRLMPG RMIGVTRDMD GNDAYRLALQ TREQHIRRDK ATSNICTAQA 360
  361 LLANMSAMYA IYHGPEGLKA MANRIHHFTL TLQTGVLGAG HEVINKNFFD TLHIRLGGGQ 420
  421 SLEDLKERAE HKRINLRYLE DDTVGVALDE TVSVADVDDL LWVFKAE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.522879
Match: 1wytA
Description: Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in apo form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycine dehydrogenase (decarboxylating) activity 8.00572280567771 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 8.00572280567771 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors 3.14486270422678 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
transferase activity 1.44093490824786 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
methyltransferase activity 0.681623261233707 bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity 0.619695949258279 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.60304280865376 bayes_pls_golite062009
glycine hydroxymethyltransferase activity 0.271623203801431 bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity 0.234399054481664 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [468-985]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASVEHILARK DVLKNSIENS KFLRTSPYLQ HPIFQSYHSE SRMVRYMKKL ENKDISLVHS  60
   61 MIPLGSCTMK LNSTTEMMPC SFRHFTDIHP FAPVEQAQGF HQMFKELEHD LCEITGYDRI 120
  121 SFQPNSGAQG EYAGLRAIRS YHEHRNEGHR NICLIPISAH GTNPASAQMA GMKVEPIRIL 180
  181 SNGSIDMAHL RAKAEEHAHE LSCLMITYPS TMGVFEETVA DICTLIHKHG GQVYLDGANM 240
  241 NAQVGLCRPG DYGSDVSHLN LHKTFCIPHG GGGPGMGPIG VKAHLAPYLP GHPVVSPLSS 300
  301 EEHSFGVVSA APFGSSAILP ISWSYIKLMG SRGLKRATQV AILNANYMSK RLEQHYKTLY 360
  361 KAPNSQLVAH EFILDIRDLK KSANIEAVDV AKRLMDYGFH APTMSWPVAG TLMIEPTESE 420
  421 DKEELDRFCD AMISIREEIA EIEAGRMDKA VNPLKMSPHT QAQVISDKWD RPYTREQAAF 480
  481 PAIFVKPDAK IWPTVGRIDD AYGDKHLVCT CPPILPDL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.221849
Match: 1wytB
Description: Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in apo form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycine dehydrogenase (decarboxylating) activity 8.00572280567771 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 8.00572280567771 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors 3.14486270422678 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
transferase activity 1.44093490824786 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
methyltransferase activity 0.681623261233707 bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity 0.619695949258279 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.60304280865376 bayes_pls_golite062009
glycine hydroxymethyltransferase activity 0.271623203801431 bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity 0.234399054481664 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle