Protein Overview: Timp-PB

General Information:
Name(s) found:	Timp-PB / FBpp0081722 [FlyBase]
Description(s) found: Found 33 descriptions. SHOW ALL	The gene Tissue inhibitor of metalloproteases is referred to in FlyBase by the symbol Dmel\Timp (CG6281, FBgn0025879). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6029597..6038710. It has the cytological map location 86A1. There is experimental evidence that it has the molecular function</span>: metalloendopeptidase inhibitor activity. There is experimental evidence that it is involved in the biological process</span>: wing disc morphogenesis; phototaxis; delamination; imaginal disc-derived wing expansion; cell adhesion. 6 alleles are reported. The phenotypes of these alleles are annotated with: adult abdomen; larval dorsal trunk; wing. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	210 amino acids
Gene Ontology:
Cellular Component:	dendrite [IMP] extracellular region [ISS] proteinaceous extracellular matrix [IEA]
Biological Process:	delamination [IMP] wing disc morphogenesis [IMP] imaginal disc-derived wing expansion [IMP] phototaxis [IMP] cell adhesion [IMP]
Molecular Function:	protein binding [IEA] metalloendopeptidase inhibitor activity [IDA][ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLRKHLGLL TLLLVAVFAF YGRPADACSC MPSHPQTHFA QADYVVQLRV LRKSDTIEPG  60
   61 RTTYKVHIKR TYKATSEARR MLRDGRLSTP QDDAMCGINL DLGKVYIVAG RMPTLNICSY 120
  121 YKEYTRMTIT ERHGFSGGYA KATNCTVTPC FGERCFKGRN YADTCKWSPF GKCETNYSAC 180
  181 MPHKVQTVNG VISRCRWRRT QLYRKCMSNP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
cytokine activity	2.84942762917954	bayes_pls_golite062009
chemokine activity	2.03758679635269	bayes_pls_golite062009
chemokine receptor binding	2.03758679635269	bayes_pls_golite062009
G-protein-coupled receptor binding	2.02944363005256	bayes_pls_golite062009
metalloendopeptidase inhibitor activity	1.72655910025353	bayes_pls_golite062009
metalloenzyme regulator activity	1.72655910025353	bayes_pls_golite062009
metalloenzyme inhibitor activity	1.72655910025353	bayes_pls_golite062009
endopeptidase inhibitor activity	1.69053016130359	bayes_pls_golite062009
peptidase inhibitor activity	1.63402812071232	bayes_pls_golite062009
binding	1.57363735103063	bayes_pls_golite062009
enzyme inhibitor activity	1.54714635439345	bayes_pls_golite062009
integrin binding	1.46644476563928	bayes_pls_golite062009
protein binding	0.991421648561387	bayes_pls_golite062009
receptor binding	0.927008627415107	bayes_pls_golite062009
enzyme regulator activity	0.0580682428355711	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..210]	PSI-BLAST	62.221849	HUMAN TISSUE INHIBITOR OF METALLOPROTEINASE-2

Protein Overview: Timp-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: