Protein Overview: neur-PA

General Information:
Name(s) found:	neur-PA / FBpp0081481 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7299131\|gb\|AAF54330.1\| neuralized, isoform A [Drosophila melanogaster] [NCBI NR] pir\|\|S35503 finger protein neuralized - fruit fly (Drosophila melanogaster) [NCBI NR] gi\|34223722\|sp\|P29503.2\|NEUR_DROME RecName: Full=Protein neuralized [NCBI NR] gi\|17136356\|ref\|NP_476652.1\| neuralized, isoform A [Drosophila melanogaster] [NCBI NR] gi\|157028\|gb\|AAA28403.1\| zinc finger protein [Drosophila melanogaster] [NCBI NR] Protein neuralized OS=Drosophila melanogaster GN=neur PE=1 SV=2 [Swiss-Prot] The gene neuralized is referred to in FlyBase by the symbol Dmel\neur (CG11988, FBgn0002932). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4846068..4865189. It has the cytological map location 85C2-85C3. There is experimental evidence that it has the molecular function</span>: ubiquitin-protein ligase activity. There is experimental evidence for 16 unique biological process</span> terms, many of which group under: anatomical structure development; sensory organ development; organ development; organ morphogenesis; behavior; regulation of developmental process; regulation of biological process; locomotory behavior; regulation of neurogenesis; protein localization; neuromuscular process; behavioral interaction between organisms; response to chemical stimulus. 91 alleles are reported. The phenotypes of these alleles are annotated with 38 unique terms, many of which group under: peripheral nervous system; adult segment; nervous system; embryonic nervous system; organ system; adult mesothoracic segment; external compound sense organ; embryonic glial cell; external sensory organ precursor cell; multi-cell-component structure. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] >CG11988-PA translation from_gene[CG11988 neur FBgn0002932] seq_release:3 mol_weight=82326 cds_boundaries:(3R:4,847,533..4,859,186[-]) aa_length:754 transcript_info:[CG11988-RA seq_release:3] gene_info:[gene symbol:neur FBgn0002932 gene_boundaries:(3R: [hmr_yeast5_DM3-1_pombe.fasta] (P29503) Neuralized protein [DrosMelano7227.FASTAC.txt] (AE003681) neur gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG11988-PA, isoform A [Drosophila melanogaster]gi\|17136356\|ref\|NP_476652.1\| CG11988-PA [Drosophila melanogaster]gi\|157028\|gb\|AAA28403.1\| zinc finger protein [Drosophila melanogaster]gi\|486806\|pir\|\|S35503 finger protein neuralized - fruit fly (Drosophil [nrdb_11152004_Chlamydomonas] type=protein; loc=3R:complement(4847515..4847766,4847826..4849567,4858901..4859171); ID=FBpp0081481; name=neur-PA; parent=FBgn0002932,FBtr0082003; dbxref=FlyBase:FBpp0081481,FlyBase_Annotation_IDs:CG11988-PA,GB_protein:AAF54330.1,REFSEQ:NP_476652,GB_prote [fly-100309-contam.fasta] CG11988-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] zinc finger protein [Drosophila melanogaster] [nr-271106-contam.fasta] neuralized CG11988-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Protein neuralized [nr-271106-contam.fasta] type=protein; loc=3R:complement(4847515..4847766,4847826..4849567,4858901..4859171); ID=FBpp0081481; name=neur-PA; parent=FBgn0002932,FBtr0082003; dbxref=FlyBase:FBpp0081481,FlyBase_Annotation_IDs:CG11988-PA,GB_protein:AAF54330.1,REFSEQ:NP_476652,GB_protein:AAF54330; MD5=7aeb40ae136a109150a7ff37b108ef3d; length=754; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3R:complement(4847515..4847766,4847826..4849567,4858901..4859171); ID=FBpp0081481; name=neur-PA; parent=FBgn0002932,FBtr0082003; dbxref=FlyBase:FBpp0081481,FlyBase_Annotation_IDs:CG11988-PA,GB_protein:AAF54330.1,REFSEQ:NP_476652,GB_protein:AAF54330; MD5=7aeb40ae136a109150a7ff37b108ef3d; length=754; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3R:complement(4847515..4847766,4847826..4849567,4858901..4859171); ID=FBpp0081481; name=neur-PA; parent=FBgn0002932,FBtr0082003; dbxref=FlyBase:FBpp0081481,FlyBase_Annotation_IDs:CG11988-PA,GB_protein:AAF54330.1,REFSEQ:NP_476652,GB_protein:AAF54330,FlyMine:FBpp0081481,modMine:FBpp0081481; MD5=7aeb40ae136a109150a7ff37b108ef3d; length=754; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3R:complement(join(9033179..9033449,9022104..9023845,9021793..9022044)); ID=FBpp0081481; name=neur-PA; parent=FBgn0002932,FBtr0082003; dbxref=FlyBase:FBpp0081481,FlyBase_Annotation_IDs:CG11988-PA,GB_protein:AAF54330.1,REFSEQ:NP_476652,GB_protein:AAF54330,FlyMine:FBpp0081481,modMine:FBpp0081481; MD5=7aeb40ae136a109150a7ff37b108ef3d; length=754; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3R:complement(join(9033179..9033449,9022104..9023845,9021793..9022044)); ID=FBpp0081481; name=neur-PA; parent=FBgn0002932,FBtr0082003; dbxref=FlyBase:FBpp0081481,FlyBase_Annotation_IDs:CG11988-PA,GB_protein:AAF54330.1,REFSEQ:NP_476652,GB_protein:AAF54330,FlyMine:FBpp0081481,modMine:FBpp0081481; MD5=7aeb40ae136a109150a7ff37b108ef3d; length=754; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0081481 type=protein; loc=3R:complement(join(9033179..9033449,9022104..9023845,9021793..9022044)); ID=FBpp0081481; name=neur-PA; parent=FBgn0002932,FBtr0082003; dbxref=FlyBase:FBpp0081481,FlyBase_Annotation_IDs:CG11988-PA,GB_protein:AAF54330.1,REFSEQ:NP_476652,GB_protein:AAF54330,FlyMine:FBpp0081481,modMine:FBpp0081481; MD5=7aeb40ae136a109150a7ff37b108ef3d; length=754; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3R:complement(join(9033179..9033449,9022104..9023845,9021793..9022044)); ID=FBpp0081481; name=neur-PA; parent=FBgn0002932,FBtr0082003; dbxref=FlyBase:FBpp0081481,FlyBase_Annotation_IDs:CG11988-PA,GB_protein:AAF54330.1,REFSEQ:NP_476652,GB_protein:AAF54330,UniProt/Swiss-Prot:P29503,FlyMine:FBpp0081481,modMine:FBpp0081481; MD5=7aeb40ae136a109150a7ff37b108ef3d; length=754; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	754 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS] perinuclear region of cytoplasm [IDA] cytoplasm [IDA] plasma membrane [IDA]
Biological Process:	regulation of Notch signaling pathway [IMP] mesoderm development [IMP] nervous system development [IMP][NAS] imaginal disc-derived wing morphogenesis [IMP] protein localization [IMP] peripheral nervous system development [IMP] regulation of compound eye photoreceptor development [IMP] asymmetric cell division [TAS] brain morphogenesis [IMP] ectoderm development [TAS] olfactory behavior [IMP] inter-male aggressive behavior [IMP] compound eye development [IMP][TAS] positive regulation of Notch signaling pathway [TAS] sensory organ development [IMP] locomotion involved in locomotory behavior [IMP] startle response [IMP] ovarian follicle cell development [TAS] sensory organ precursor cell fate determination [IMP] germ-line stem cell maintenance [IMP]
Molecular Function:	DNA binding [ISS] ubiquitin-protein ligase activity [IDA] zinc ion binding [IEA] protein binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLSDIPANY MQGSHPHLTL HPQQQHHQNQ QHLQHLQQMQ QLHNAMPTPA QQAAQVLAME  60
   61 SNELLMSTKD KLSSKKKMHL LKKIKKRFGL VRRSPSSCPG PNNLPPLQFH SVHGDNIRIS 120
  121 RDGTLARRFE SFCRAITFSA RPVRINERIC VKFAEISNNW NGGIRFGFTS NDPVTLEGTL 180
  181 PKYACPDLTN RPGFWAKALH EQYCEKDNIL YYYVNGAGDV IYGINNEEKG VILTGIDTRS 240
  241 LLWTVIDIYG NCTGIEFLDS RIYMYQQQPA AIPMATVPAQ QQQMPQPAAN ASSALNSHHP 300
  301 HQQSRRSLPG HTAAIEHDLE RHVMPSLQSL HLAGNGGSVA SVEQAAIAHD LANGLPPLRY 360
  361 NANGRLIPVP FHNTKGRNVR LSQDRFVASR TESDFCQGYV FTARPIRIGE KLIVQVLKTE 420
  421 QMYVGALALG LTSCNPAMLQ PNDLPNDSDF LLDRPEYWVV SKDIAAAPQR GDEIAFFVAP 480
  481 NGEVSISKNN GPAVVVMHVD QSLQLWAFLD VYGSTQSLRM FRQQLPNMVA YPSQPQVNVN 540
  541 ASSSSACNAA STSRMLPMTE SMSSLNAGAT AKLLHHPSQL SVAQSTSTLA SAGGVNGSRM 600
  601 ISMPSNGDIL QIQPNGGGTV LVVNLPPASS SHDINGQLAA RPTATVTSSG VLAGACSSGT 660
  661 LISTTSSQYI EQPIANSTNN AANKWKDSLS DQQSTDSSAE CTICYENPID SVLYMCGHMC 720
  721 MCYDCAIEQW RGVGGGQCPL CRAVIRDVIR TYTT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..93]	deduced	N/A	No confident structure predictions are available.
2	View Details	[94..263]	PSI-BLAST	63.522879	No description for 2yueA was found.
3	View Details	[264..338]	deduced	N/A	No confident structure predictions are available.
4	View Details	[339..532]	FFAS03	6.64	No description for 2yueA was found.
5	View Details	[533..629]	deduced	N/A	No confident structure predictions are available.
6	View Details	[630..754]	PSI-BLAST	6.09691	No description for 2cklB was found.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: neur-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: