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Protein Overview: Sp7-PB

General Information:
Name(s) found: Sp7-PB / FBpp0081238 [FlyBase]
Description(s) found:
Found 15 descriptions.
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  • The gene Serine protease 7 is referred to in FlyBase by the symbol Dmel\Sp7 (CG3066, FBgn0037515). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3585508..3589154. It has the cytological map location 84D14-84E1. Based on sequence similarity, it is predicted to have molecular function</span>: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: melanization defense response; positive regulation of melanization defense response. 9 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 241 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEA][NAS]
    positive regulation of melanization defense response [IMP]
    defense response [NAS]
    melanization defense response [IMP][NAS]
    Molecular Function: serine-type endopeptidase activity [IEA][ISS][NAS]
    serine-type peptidase activity [NAS]
    serine-type carboxypeptidase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALLEYVDNR GRRELSCGGS LINNRYVLTA AHCVIGAVET EVGHLTTVRL GEYDTSKDVD  60
   61 CIDDICNQPI LQLGIEQATV HPQYDPANKN RIHDIALLRL DRPVVLNEYI QPVCLPLVST 120
  121 RMAINTGELL VVSGWGRTTT ARKSTIKQRL DLPVNDHDYC ARKFATRNIH LISSQLCVGG 180
  181 EFYRDSCDGD SGGPLMRRGF DQAWYQEGVV SFGNRCGLEG WPGVYTRVAD YMDWIVETIR 240
  241 P

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..241] PSI-BLAST 58.522879 No description for 2olgA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle