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Protein Overview: alpha-Est7-PA

General Information:
Name(s) found: alpha-Est7-PA / FBpp0081074 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Ã?&#142;Ã?±-Esterase-7 is referred to in FlyBase by the symbol Dmel\Ã?&#142;Ã?±-Est7 (CG1112, FBgn0015575). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3345284..3349476. It has the cytological map location 84D9. There is experimental evidence that it has the molecular function</span>: carboxylesterase activity. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 572 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    cytoplasm [IDA]
    Biological Process: biological_process [ND]
    Molecular Function: carboxylesterase activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKNLGFVER LRWRLKTIEH KVQQYRQSTN ETVVADTEYG QVRGIKRLSL YDVPYFSFEG  60
   61 IPYAQPPVGE LRFKAPQRPI PWERVRDCSQ PKDKAVQVQF VFDKVEGSED CLYLNVYTNN 120
  121 VKPDKARPVM VWIHGGGFII GEANREWYGP DYFMKEDVVL VTIQYRLGAL GFMSLKSPEL 180
  181 NVPGNAGLKD QVLALKWIKN NCASFGGDPN CITVFGESAG GASTHYMMLT DQTQGLFHRG 240
  241 ILQSGSAICP WAYNGDITHN PYRIAKLVGY KGEDNDKDVL EFLQNVKAKD LIRVEENVLT 300
  301 LEERMNKIMF AFGPSLEPFS TPECVISKPP KEMMKTAWSN SIPMFIGNTS YEGLLWVPEV 360
  361 KLMPQVLQQL DAGTPFIPKE LLATEPSKEK LDSWSAQIRD VHRTGSESTP DNYMDLCSIY 420
  421 YFVFPALRVV HSRHAYAAGA PVYFYRYDFD SEELIFPYRI MRLGRGVKGV SHADDLSYQF 480
  481 SSLLARRLPK ESREYRNIER TVGIWTQFAA TGNPYSEKIN GMDTLTIDPV RKSDEVIKCL 540
  541 NISDDLKFID LPEWPKLKVW ESLYDDNKDL LF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..572] PSI-BLAST 108.0 Mammalian carboxylesterase (liver carboxylesterase I)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acetylcholinesterase activity
    		•  6.01557374116734 bayes_pls_golite062009
  • juvenile hormone epoxide hydrolase activity
    		•  5.69212503305375 bayes_pls_golite062009
  • epoxide hydrolase activity
    		•  4.54228071084398 bayes_pls_golite062009
  • ether hydrolase activity
    		•  3.98161932704074 bayes_pls_golite062009
  • cholinesterase activity
    		•  3.53190978140684 bayes_pls_golite062009
  • hydrolase activity, acting on ether bonds
    		•  3.22022434415297 bayes_pls_golite062009
  • choline binding
    		•  2.44944581139315 bayes_pls_golite062009
  • carboxylesterase activity
    		•  2.10340684157921 bayes_pls_golite062009
  • lipase activity
    		•  1.95656432876646 bayes_pls_golite062009
  • hydrolase activity
    		•  1.89798820741335 bayes_pls_golite062009
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.12989474350467 bayes_pls_golite062009
  • palmitoyl-CoA hydrolase activity
    		•  1.05694246543302 bayes_pls_golite062009
  • binding
    		•  0.978846093152455 bayes_pls_golite062009
  • peptidase activity
    		•  0.946698616106528 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.786172015267385 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.715547007602635 bayes_pls_golite062009
  • palmitoyl-(protein) hydrolase activity
    		•  0.662918274852389 bayes_pls_golite062009
  • serine hydrolase activity
    		•  0.527527404338 bayes_pls_golite062009
  • acylglycerol lipase activity
    		•  0.345658974420231 bayes_pls_golite062009
  • receptor binding
    		•  0.338398047466334 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  0.33062249657108 bayes_pls_golite062009
  • heparin binding
    		•  0.219437684278316 bayes_pls_golite062009
  • phospholipase activity
    		•  0.1336535306364 bayes_pls_golite062009
  • triglyceride lipase activity
    		•  0.05324087110088 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle