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Protein Overview: Hr83-PA

General Information:
Name(s) found: Hr83-PA / FBpp0081210 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene Hormone receptor 83 is referred to in FlyBase by the symbol Dmel\Hr83 (CG10296, FBgn0037436). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2174965..2176234. It has the cytological map location 83E4. Based on sequence similarity, it is predicted to have molecular function</span>: steroid hormone receptor activity; ligand-dependent nuclear receptor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: regulation of transcription, DNA-dependent. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 278 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: regulation of transcription, DNA-dependent [IEA]
    Molecular Function: zinc ion binding [IEA]
    transcription factor activity [IEA]
    ligand-dependent nuclear receptor activity [ISS][NAS]
    steroid hormone receptor activity [ISS]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNFSACAVC GDQSSGKHYG VSCCDGCSCF FKRSVRRGSS YACIALVGNC VVDKARRNWC  60
   61 PSCRFQRCLA VGMNAAAVQE ERGPRNQQVA LYRTGRRQAP PSQAAPSPTP HSQALHFQIL 120
  121 AQILVTCLRQ AKANEQFALL DRCQQDAIFQ VVWSEIFVLR ASHWSLDISA MIDGCGDEQL 180
  181 KRLICEAHQL RADVLELNFM ESLILCRKEL AINAEYAVIL GSHSKAALIS LARYTLQQSN 240
  241 YLRFGQLLLG LRQLCLRRFD CALSCMFRSV VRDILKTL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] PSI-BLAST 14.30103 No description for 2hanB was found.
    2 View Details [80..278] PSI-BLAST 18.69897 Ultraspiracle protein, usp

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.61050300164895 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.50407228091742 bayes_pls_golite062009
  • DNA binding
    		•  0.49201337012822 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.46319437988224 bayes_pls_golite062009
  • protein binding
    		•  0.282518360997624 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.49959085852672 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.0250131205344 bayes_pls_golite062009
  • DNA binding
    		•  1.80621810855252 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.77087213956344 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
    		•  1.59526038839002 bayes_pls_golite062009
  • protein binding
    		•  1.05275282683843 bayes_pls_golite062009
  • transcription factor activity
    		•  0.93864695040516 bayes_pls_golite062009
  • receptor activity
    		•  0.760202606593765 bayes_pls_golite062009
  • transcription activator activity
    		•  0.603009050492 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.57252716225138 bayes_pls_golite062009
  • steroid hormone receptor activity
    		•  0.24565577256251 bayes_pls_golite062009
  • transcription factor binding
    		•  0.22252559443603 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.61

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle