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View Structure Prediction Details

Protein: Hr83-PA
Organism: Drosophila melanogaster
Length: 278 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hr83-PA.

Description E-value Query
Range
Subject
Range
gi|68396885 - gi|68396885|ref|XP_683221.1| PREDICTED: similar to retinoid X receptor-alpha [Danio rerio]
226.0 [0..3] [273..204]
gi|109070630 - gi|109070630|ref|XP_001108780.1| PREDICTED: similar to retinoid X receptor, beta [Macaca mulatta]
223.0 [0..4] [273..363]
gi|114627460 - gi|114627460|ref|XP_520345.2| PREDICTED: hypothetical protein [Pan troglodytes]
223.0 [0..3] [273..270]
gi|39645799 - gi|39645799|gb|AAH63827.1| RXRA protein [Homo sapiens]
222.0 [0..3] [273..185]
gi|21310111 - gi|21310111|gb|AAM46151.1|AF378829_1 nuclear hormone receptor RXR [Branchiostoma floridae]
222.0 [0..3] [273..156]
gi|83318203 - gi|83318203|gb|AAI08461.1| Rxrb-a protein [Xenopus laevis]
222.0 [0..1] [273..131]
gi|148747360, gi... - gi|149039209|gb|EDL93429.1| retinoid X receptor alpha, isoform CRA_a [Rattus norvegicus], gi|1487473...
222.0 [0..1] [273..132]
gi|73972492 - gi|73972492|ref|XP_862609.1| PREDICTED: similar to retinoid X receptor, beta isoform 8 [Canis famili...
221.0 [0..4] [273..201]
RXRA_MOUSE - Retinoic acid receptor RXR-alpha OS=Mus musculus GN=Rxra PE=1 SV=1
221.0 [0..3] [273..136]

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Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNFSACAVC GDQSSGKHYG VSCCDGCSCF FKRSVRRGSS YACIALVGNC VVDKARRNWC  60
   61 PSCRFQRCLA VGMNAAAVQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.30103
Match: 2hanB
Description: No description for 2hanB was found.

Predicted functions:

Term Confidence Notes
binding 1.61050300164895 bayes_pls_golite062009
transcription regulator activity 0.50407228091742 bayes_pls_golite062009
DNA binding 0.49201337012822 bayes_pls_golite062009
nucleic acid binding 0.46319437988224 bayes_pls_golite062009
protein binding 0.282518360997624 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [80-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EERGPRNQQV ALYRTGRRQA PPSQAAPSPT PHSQALHFQI LAQILVTCLR QAKANEQFAL  60
   61 LDRCQQDAIF QVVWSEIFVL RASHWSLDIS AMIDGCGDEQ LKRLICEAHQ LRADVLELNF 120
  121 MESLILCRKE LAINAEYAVI LGSHSKAALI SLARYTLQQS NYLRFGQLLL GLRQLCLRRF 180
  181 DCALSCMFRS VVRDILKTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.69897
Match: 1hg4A
Description: Ultraspiracle protein, usp
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.49959085852672 bayes_pls_golite062009
transcription regulator activity 2.0250131205344 bayes_pls_golite062009
DNA binding 1.80621810855252 bayes_pls_golite062009
nucleic acid binding 1.77087213956344 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.59526038839002 bayes_pls_golite062009
protein binding 1.05275282683843 bayes_pls_golite062009
transcription factor activity 0.93864695040516 bayes_pls_golite062009
receptor activity 0.760202606593765 bayes_pls_golite062009
transcription activator activity 0.603009050492 bayes_pls_golite062009
sequence-specific DNA binding 0.57252716225138 bayes_pls_golite062009
steroid hormone receptor activity 0.24565577256251 bayes_pls_golite062009
transcription factor binding 0.22252559443603 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle