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Protein Overview: MTA1-like-PB

General Information:
Name(s) found: MTA1-like-PB / FBpp0078383 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene MTA1-like is referred to in FlyBase by the symbol Dmel\MTA1-like (CG2244, FBgn0027951). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1464809..1474459. It has the cytological map location 83B7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: transcription factor activity; sequence-specific DNA binding; zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 844 amino acids

    Gene Ontology:
    Cellular Component: histone deacetylase complex [IDA]
    Biological Process: phagocytosis, engulfment [IMP]
    regulation of transcription, DNA-dependent [IEA]
    Molecular Function: transcription factor activity [IEA]
    zinc ion binding [IEA]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATNMYRVGD YVYVETTPNS PYLIRRIEEL NKNQTGNVEA KVMCFYRRRD LPNPLVQLAD  60
   61 KHQPALDEER TSPTQTSGGG GSATGNSGSN SSGTSNNNSS STAIGGGAGG SGGAGGDAEK 120
  121 GEALTSKQRY QIKHRELFLS RQVESIPATQ IRGKCSVTLL NETESLQSYL NKDDTFFYCL 180
  181 VFDPNQKTLL ADKGEIRVGS RYQCDIPAKL KDTATDDRKL EELESLVWTP EHSLTDRKID 240
  241 QFLVVSRSIG TFARALDCSS SVKQPSLHMS AAAASRDITL FHAMNILHKH EYSIEESMSS 300
  301 LVPSTGPVLC RDEIEDWSAS EANLFEEALE KYGKDFNDIR QDFLPWKTLK QIIEYYYMWK 360
  361 TTDRYVQQKR VKAVEAELKL KQVYIPQYNN NGKGNGTSTK AGGGIYNGTT NGSTDLSSNG 420
  421 KPCESCGTTK SSQWNSVSSG HSTSRLCLSC WEYWRRYGSM KSATKGDAGE GDAKKKSSSA 480
  481 ASTPTATLAG LATTPTAVVD LNDDEKISDL TNRQLHRCSI VNCGKEFKLK THLARHYAQA 540
  541 HGIAISSGSP RPIMKTRTAF YLHTNPMTRV ARAICRSIVK PKKAARQSAY AINAMLVKQE 600
  601 FTNRISGKSQ AEIKKLLLLK PKDRGSVTKI ANRLGAPGSG PHEWLVLTPK DKMPLPAVVS 660
  661 FPKPPKAPDG SLVYDRVPNK SPDVVAVPAD KELTIIPTQA TSTIRKRAHE DQQLNGTEVT 720
  721 IVPSGPPAKR PNKDPMPSHC PSPEQFAAMM AASGQPLSRH HLNGKQKIAQ MARGGNGRKQ 780
  781 VISWMDAPDD VYFRANDTHK KTRKILSAVD LRRAARKPWR TLPIKPAAPE PSSRPIESQI 840
  841 VILD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..215] FFAS03 2.72 Crystal structure of the proximal BAH domain of polybromo
    2 View Details [216..322] deduced N/A No confident structure predictions are available.
    3 View Details [323..372] PSI-BLAST 19.221849 Solution structure of the myb-like DNA-binding domain of mouse MTA3 protein
    4 View Details [373..604] deduced N/A No confident structure predictions are available.
    5 View Details [605..764] MSA 3.304996 View MSA. No confident structure predictions are available.
    6 View Details [765..844] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.87991790206998 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.122580758085 bayes_pls_golite062009
  • DNA binding
    		•  1.98453325263719 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.93681952439958 bayes_pls_golite062009
  • transcription factor activity
    		•  1.36872096268289 bayes_pls_golite062009
  • protein deacetylase activity
    		•  1.30097338817679 bayes_pls_golite062009
  • histone deacetylase activity
    		•  1.21500914041004 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.09150919349912 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.03881604759993 bayes_pls_golite062009
  • protein binding
    		•  1.03780839342631 bayes_pls_golite062009
  • deacetylase activity
    		•  0.690301184840273 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.187173982490585 bayes_pls_golite062009
  • transcription activator activity
    		•  0.174325083775401 bayes_pls_golite062009
  • transcription factor binding
    		•  0.14097776282047 bayes_pls_golite062009
  • chromatin binding
    		•  0.123933030155299 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle