Protein Overview: Nmdar1-PA

General Information:
Name(s) found:	Nmdar1-PA / FBpp0078410 [FlyBase]
Description(s) found: Found 25 descriptions. SHOW ALL	The gene NMDA receptor 1 is referred to in FlyBase by the symbol Dmel\Nmdar1 (CG2902, FBgn0010399). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1334544..1349046. It has the cytological map location 83A6-83A7. There is experimental evidence that it has the molecular function</span>: ionotropic glutamate receptor activity. There is experimental evidence that it is involved in the biological process</span>: olfactory learning; long-term memory. 15 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	997 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] outer membrane-bounded periplasmic space [IEA]
Biological Process:	long-term memory [IMP] ion transport [IEA] olfactory learning [IMP]
Molecular Function:	extracellular-glutamate-gated ion channel activity [IEA] ionotropic glutamate receptor activity [IDA] N-methyl-D-aspartate selective glutamate receptor activity [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMAEFVFCR PLFGLAIVLL VAPIDAAQRH TASDNPSTYN IGGVLSNSDS EEHFSTTIKH  60
   61 LNFDQQYVPR KVTYYDKTIR MDKNPIKTVF NVCDKLIENR VYAVVVSHEQ TSGDLSPAAV 120
  121 SYTSGFYSIP VIGISSRDAA FSDKNIHVSF LRTVPPYYHQ ADVWLEMLSH FAYTKVIIIH 180
  181 SSDTDGRAIL GRFQTTSQTY YDDVDVRATV ELIVEFEPKL ESFTEHLIDM KTAQSRVYLM 240
  241 YASTEDAQVI FRDAGEYNMT GEGHVWIVTE QALFSNNTPD GVLGLQLEHA HSDKGHIRDS 300
  301 VYVLASAIKE MISNETIAEA PKDCGDSAVN WESGKRLFQY LKSRNITGET GQVAFDDNGD 360
  361 RIYAGYDVIN IREQQKKHVV GKFSYDSMRA KMRMRINDSE IIWPGKQRRK PEGIMIPTHL 420
  421 RLLTIEEKPF VYVRRMGDDE FRCEPDERPC PLFNNSDATA NEFCCRGYCI DLLIELSKRI 480
  481 NFTYDLALSP DGQFGHYILR NNTGAMTLRK EWTGLIGELV NERADMIVAP LTINPERAEY 540
  541 IEFSKPFKYQ GITILEKKPS RSSTLVSFLQ PFSNTLWILV MVSVHVVALV LYLLDRFSPF 600
  601 GRFKLSHSDS NEEKALNLSS AVWFAWGVLL NSGIGEGTPR SFSARVLGMV WAGFAMIIVA 660
  661 SYTANLAAFL VLERPKTKLS GINDARLRNT MENLTCATVK GSSVDMYFRR QVELSNMYRT 720
  721 MEANNYATAE QAIQDVKKGK LMAFIWDSSR LEYEASKDCE LVTAGELFGR SGYGIGLQKG 780
  781 SPWTDAVTLA ILEFHESGFM EKLDKQWIFH GHVQQNCELF EKTPNTLGLK NMAGVFILVG 840
  841 VGIAGGVGLI IIEVIYKKHQ VKKQKRLDIA RHAADKWRGT IEKRKTIRAS LAMQRQYNVG 900
  901 LNSTHAPGTI SLAVDKRRYP RLGQRLGPER AWPGDAADVL RIRRPYELGN PGQSPKVMAA 960
  961 NQPGMPMPML GKTRPQQSVL PPRYSPGYTS DVSHLVV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
voltage-gated potassium channel activity	5.71321890307691	bayes_pls_golite062009
potassium channel activity	5.64444696546351	bayes_pls_golite062009
metal ion transmembrane transporter activity	5.60647618241473	bayes_pls_golite062009
voltage-gated cation channel activity	5.2851122235184	bayes_pls_golite062009
voltage-gated ion channel activity	5.12283267339494	bayes_pls_golite062009
voltage-gated channel activity	5.09999533279013	bayes_pls_golite062009
cation channel activity	5.09551684793166	bayes_pls_golite062009
cation transmembrane transporter activity	4.88789838906314	bayes_pls_golite062009
ion transmembrane transporter activity	4.80939024913503	bayes_pls_golite062009
ion channel activity	4.50553553033114	bayes_pls_golite062009
gated channel activity	4.47618233399604	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.43208330555032	bayes_pls_golite062009
substrate-specific channel activity	4.39833449623615	bayes_pls_golite062009
passive transmembrane transporter activity	4.38139555510307	bayes_pls_golite062009
channel activity	4.38139555510307	bayes_pls_golite062009
inward rectifier potassium channel activity	3.1911169166902	bayes_pls_golite062009
transporter activity	2.77619896060397	bayes_pls_golite062009
transmembrane transporter activity	2.65613366364107	bayes_pls_golite062009
substrate-specific transporter activity	2.60593795082679	bayes_pls_golite062009
ligand-gated ion channel activity	2.41007732307954	bayes_pls_golite062009
ligand-gated channel activity	2.41007732307954	bayes_pls_golite062009

No functions predicted.

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..532]	PSI-BLAST	52.0	No description for 2e4uA was found.
2	View Details	[533..673]	FFAS03	2.58	Inward rectifier potassium channel Kirbac1.1
3	View Details	[674..811]	PSI-BLAST	23.69897	N-methyl-D-aspartate receptor subunit 1
4	View Details	[812..893]	MSA	2.395994	View MSA. No confident structure predictions are available.
5	View Details	[894..997]	MSA	3.179997	View MSA. No confident structure predictions are available.

Protein Overview: Nmdar1-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: