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Protein Overview: abs-PA

General Information:
Name(s) found: abs-PA / FBpp0078606 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • The gene abstrakt is referred to in FlyBase by the symbol Dmel\abs (CG14637, FBgn0015331). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:58765..60763. It has the cytological map location 82A1. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent helicase activity; helicase activity. It is reported to be involved in the biological process</span>: nervous system development; apoptosis; anatomical structure morphogenesis; establishment of cell polarity. 25 alleles are reported. The phenotypes of these alleles are annotated with: retina; central nervous system; Bolwig's nerve; photoreceptor cell; longitudinal connective; ommatidium. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 619 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    Biological Process: apoptosis [NAS]
    nervous system development [NAS]
    establishment of cell polarity [NAS]
    anatomical structure morphogenesis [NAS]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: nucleic acid binding [IEA]
    ATP binding [IEA]
    zinc ion binding [IEA]
    ATP-dependent helicase activity [ISS]
    helicase activity [ISS]
    ATP-dependent RNA helicase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHVKRYRRS SKSSEEGDLD NEDYVPYVPV KERKKQHMIK LGRIVQLVSE TAQPKSSSEN  60
   61 ENEDDSQGAH DVETWGRKYN ISLLDQHTEL KKIAEAKKLS AVEKQLREEE KIMESIAQQK 120
  121 ALMGVAELAK GIQYEQPIKT AWKPPRYIRE MSEEEREAVR HELRILVEGE TPSPPIRSFR 180
  181 EMKFPKGILN GLAAKGIKNP TPIQVQGLPT VLAGRDLIGI AFTGSGKTLV FVLPVIMFAL 240
  241 EQEYSLPFER NEGPYGLIIC PSRELAKQTH EIIQHYSKHL QACGMPEIRS CLAMGGLPVS 300
  301 EALDVISRGV HIVVATPGRL MDMLDKKILT LDMCRYLCMD EADRMIDMGF EEDVRTIFSF 360
  361 FKGQRQTLLF SATMPKKIQN FARSALVKPV TINVGRAGAA SMNVTQQVEY VKQEAKVVYL 420
  421 LDCLQKTAPP VLIFAEKKQD VDCIHEYLLL KGVEAVAIHG GKDQEERSRA VDAYRVGKKD 480
  481 VLVATDVASK GLDFPNVQHV INYDMPDDIE NYVHRIGRTG RSNTKGLATT LINKTTEQSV 540
  541 LLDLKHLLIE GKQEVPDFLD ELAPETEHQH LDLGDSHGCT YCGGLGHRIT ECPKLEAVQN 600
  601 KQASNIGRRD YLSNTAADY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..132] deduced N/A No confident structure predictions are available.
    2 View Details [133..553] PSI-BLAST 102.0 No description for 2db3A was found.
    3 View Details [554..619] PSI-BLAST 19.522879 No description for 2d7dA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.79

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle