Protein Overview: Hem-PA

General Information:
Name(s) found:	Hem-PA / FBpp0078162 [FlyBase]
Description(s) found: Found 26 descriptions. SHOW ALL	The gene HEM-protein is referred to in FlyBase by the symbol Dmel\Hem (CG5837, FBgn0011771). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:22277454..22281292. It has the cytological map location 79D4. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; myoblast fusion; central nervous system development; cell projection assembly; bristle morphogenesis; neuromuscular junction development; axonogenesis; cortical actin cytoskeleton organization; cytoskeleton organization; phagocytosis, engulfment. 21 alleles are reported. The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: nervous system; embryonic nervous system; organ system; multi-cell-component structure; peripheral nervous system; embryonic glial cell; commissure; adult segment; embryonic neuron; protein complex; axon; late extended germ band embryo. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1126 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [NAS] plasma membrane [NAS]
Biological Process:	regulation of cell shape [IMP] cortical actin cytoskeleton organization [IMP] neuromuscular junction development [IMP] oocyte growth [NAS] bristle morphogenesis [IMP] central nervous system development [IMP] phagocytosis, engulfment [IMP] cytoskeleton organization [IMP] axonogenesis [IMP] cell projection assembly [IMP] myoblast fusion [IMP]
Molecular Function:	protein binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARPIFPNQQ KIAEKLIILN DRGLGILTRI YNIKKACGDT KSKPGFLSEK SLESSIKFIV  60
   61 KRFPNIDVKG LNAIVNIKAE IIKSLSLYYH TFVDLLDFKD NVCELLTTMD ACQIHLDITL 120
  121 NFELTKYYLD LVVTYVSLMI VLSRVEDRKA VLGLYNAAYE LQNNQADTGF PRLGQMILDY 180
  181 EVPLKKLAEE FIPHQRLLTS ALRSLTSIYA LRNLPADKWR EMQKLSLVGN PAILLKAVRT 240
  241 DTMSCEYISL EAMDRWIIFG LLLNHQMLGQ YPEVNKIWLS ALESSWVVAL FRDEVLQIHQ 300
  301 YIQATFDGIK GYSKRIGEVK EAYNTAVQKA ALMHRERRKF LRTALKELAL IMTDQPGLLG 360
  361 PKAIFIFIGL CLARDEILWL LRHNDNPPLL KNKGKSNEDL VDRQLPELLF HMEELRALVR 420
  421 KYSQVMQRYY VQYLSGFDAT DLNIRMQSLQ MCPEDESIIF SSLYNTAAAL TVKQVEDNEL 480
  481 FYFRPFRLDW FRLQTYMSVG KAALRIAEHA ELARLLDSMV FHTRVVDNLD EILVETSDLS 540
  541 IFCFYNKMFD DQFHMCLEFP AQNRYIIAFP LICSHFQNCT HEMCPEERHH IRERSLSVVN 600
  601 IFLEEMAKEA KNIITTICDE QCTMADALLP KHCAKILSVQ SARKKKDKSK SKHFDDIRKP 660
  661 GDESYRKTRE DLTTMDKLHM ALTELCFAIN YCPTVNVWEF AFAPREYLCQ NLEHRFSRDL 720
  721 VGMVMFNQET MEIAKPSELL ASVRAYMNVL QTVENYVHID ITRVFNNCLL QQTQALDSHG 780
  781 EKTIAALYNT WYSEVLLRRV SAGNIVFSIN QKAFVPISPE GWVPFNPQEF SDLNELRALA 840
  841 ELVGPYGIKT LNETLMWHIA NQVQELKSLV STNKEVLITL RTSFDKPEVM KEQFKRLQDV 900
  901 DRVLQRMTII GVIICFRNLV HEALVDVLDK RIPFLLSSVK DFQEHLPGGD QIRVASEMAS 960
  961 AAGLLCKVDP TLATTLKSKK PEFDEGEHLT ACLLMVFVAV SIPKLARNEN SFYRATIDGH1020
 1021 SNNTHCMAAA INNIFGALFT ICGQSDMEDR MKEFLALASS SLLRLGQESD KEATRNRESI1080
 1081 YLLLDEIVKQ SPFLTMDLLE SCFPYVLIRN AYHGVYKQEQ ILGLAL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.90

Protein Overview: Hem-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: