Protein Overview: Rpn1-PA

General Information:
Name(s) found:	Rpn1-PA / FBpp0074662 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|6434946\|gb\|AAF08385.1\|AF145304_1 26S proteasome regulatory complex subunit p97 [Drosophila melanogaster] [NCBI NR] gi\|4972750\|gb\|AAD34770.1\| unknown [Drosophila melanogaster] [NCBI NR] gi\|21356859\|ref\|NP_649158.1\| Rpn1 [Drosophila melanogaster] [NCBI NR] gi\|10733350\|gb\|AAF49095.2\| Rpn1 [Drosophila melanogaster] [NCBI NR] The gene Rpn1 is referred to in FlyBase by the symbol Dmel\Rpn1 (CG7762, FBgn0028695). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19908156..19911265. It has the cytological map location 76D4. There is experimental evidence that it has the molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle elongation; cell proliferation; mitotic spindle organization; proteolysis. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG7762-PA translation from_gene[CG7762 Rpn1 FBgn0028695] seq_release:3 mol_weight=102279 cds_boundaries:(3L:19,833,729..19,836,554[+]) aa_length:919 transcript_info:[CG7762-RA seq_release:3] gene_info:[gene symbol:Rpn1 FBgn0028695 gene_boundaries:(3L: [hmr_yeast5_DM3-1_pombe.fasta] (Q9VW54) Rpn1 protein [DrosMelano7227.FASTAC.txt] (AE003515) Rpn1 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG7762-PA [Drosophila melanogaster]gi\|21356859\|ref\|NP_649158.1\| CG7762-PA [Drosophila melanogaster]gi\|4972750\|gb\|AAD34770.1\| unknown [Drosophila melanogaster]gi\|6434946\|gb\|AAF08385.1\| 26S proteasome regulatory complex subunit p97 [Drosophila melanogast [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(19908291..19910213,19910283..19911119); ID=FBpp0074662; name=Rpn1-PA; parent=FBgn0028695,FBtr0074893; dbxref=FlyBase:FBpp0074662,FlyBase_Annotation_IDs:CG7762-PA,GB_protein:AAF49095.2,REFSEQ:NP_649158,GB_protein:AAF49095; MD5=dca [fly-100309-contam.fasta] unknown [Drosophila melanogaster] [nr-271106-contam.fasta] CG7762-PA [Drosophila melanogaster] [nr-271106-contam.fasta] Rpn1 CG7762-PA [Drosophila melanogaster] [nr-271106-contam.fasta] 26S proteasome regulatory complex subunit p97 [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(19908291..19910213,19910283..19911119); ID=FBpp0074662; name=Rpn1-PA; parent=FBgn0028695,FBtr0074893; dbxref=FlyBase:FBpp0074662,FlyBase_Annotation_IDs:CG7762-PA,GB_protein:AAF49095.2,REFSEQ:NP_649158,GB_protein:AAF49095; MD5=dca0928cc63d49df0550af2d0134e7d9; length=919; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(19908291..19910213,19910283..19911119); ID=FBpp0074662; name=Rpn1-PA; parent=FBgn0028695,FBtr0074893; dbxref=FlyBase:FBpp0074662,FlyBase_Annotation_IDs:CG7762-PA,GB_protein:AAF49095.2,REFSEQ:NP_649158,GB_protein:AAF49095; MD5=dca0928cc63d49df0550af2d0134e7d9; length=919; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] 26S proteasome regulatory complex subunit p97 OS=Drosophila melanogaster GN=Rpn1 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(19908291..19910213,19910283..19911119); ID=FBpp0074662; name=Rpn1-PA; parent=FBgn0028695,FBtr0074893; dbxref=FlyBase:FBpp0074662,FlyBase_Annotation_IDs:CG7762-PA,GB_protein:AAF49095.2,REFSEQ:NP_649158,GB_protein:AAF49095,FlyMine:FBpp0074662,modMine:FBpp0074662; MD5=dca0928cc63d49df0550af2d0134e7d9; length=919; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] 26S proteasome regulatory complex subunit p97 OS=Drosophila melanogaster GN=Rpn1 PE=2 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=3L:join(19915191..19917113,19917183..19918019); ID=FBpp0074662; name=Rpn1-PA; parent=FBgn0028695,FBtr0074893; dbxref=FlyBase:FBpp0074662,FlyBase_Annotation_IDs:CG7762-PA,GB_protein:AAF49095.2,REFSEQ:NP_649158,GB_protein:AAF49095,FlyMine:FBpp0074662,modMine:FBpp0074662; MD5=dca0928cc63d49df0550af2d0134e7d9; length=919; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(19915191..19917113,19917183..19918019); ID=FBpp0074662; name=Rpn1-PA; parent=FBgn0028695,FBtr0074893; dbxref=FlyBase:FBpp0074662,FlyBase_Annotation_IDs:CG7762-PA,GB_protein:AAF49095.2,REFSEQ:NP_649158,GB_protein:AAF49095,FlyMine:FBpp0074662,modMine:FBpp0074662; MD5=dca0928cc63d49df0550af2d0134e7d9; length=919; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0074662 type=protein; loc=3L:join(19915191..19917113,19917183..19918019); ID=FBpp0074662; name=Rpn1-PA; parent=FBgn0028695,FBtr0074893; dbxref=FlyBase:FBpp0074662,FlyBase_Annotation_IDs:CG7762-PA,GB_protein:AAF49095.2,REFSEQ:NP_649158,GB_protein:AAF49095,FlyMine:FBpp0074662,modMine:FBpp0074662; MD5=dca0928cc63d49df0550af2d0134e7d9; length=919; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(19915191..19917113,19917183..19918019); ID=FBpp0074662; name=Rpn1-PA; parent=FBgn0028695,FBtr0074893; dbxref=FlyBase:FBpp0074662,FlyBase_Annotation_IDs:CG7762-PA,GB_protein:AAF49095.2,REFSEQ:NP_649158,GB_protein:AAF49095,UniProt/TrEMBL:Q9VW54,FlyMine:FBpp0074662,modMine:FBpp0074662; MD5=dca0928cc63d49df0550af2d0134e7d9; length=919; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	919 amino acids
Gene Ontology:
Cellular Component:	proteasome regulatory particle, base subcomplex [ISS][NAS] proteasome regulatory particle [IDA][ISS]
Biological Process:	cell proliferation [IMP] mitotic spindle elongation [IMP] mitotic spindle organization [IMP] proteolysis [IDA][ISS] regulation of protein catabolic process [IEA]
Molecular Function:	endopeptidase activity [IDA] binding [IEA] enzyme regulator activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGETKLEKK PLKPAASEGD AKDPKAKKDE KKDGKDKEQQ PELSDEDQQL QEELELLVQH  60
   61 LQEPDAKLYQ PTLESMAKLI RASTTSMTSV PKPLKFMRPH YETMKTVYKH MPNEQARQLC 120
  121 ADIISVLSMT MGSGKDCLAY RFLCDRKQRI GDWGHEYVRH LSGEISAHYH DTTGDFRVQL 180
  181 IELVKQIIPY NMEHNAEADA CDLLIEIDHL HLLSDFVDES AYPRVCLYLQ SCYPYVPDPD 240
  241 NTIILETALQ LSRKFNQYTQ AMRLALMLND MDKIGEIFKE PKEPAMQKQL AFMLARQQIC 300
  301 LELDELVPDY DDLMEIMSNA NLNKHFLNLA RELDIMEPKT PEDIYKSHLD NSRSRFASIQ 360
  361 VDSAKQNLAA SFVNGFVNAG FGVDKLLSED GNKWLYKNKE HGMLSATASL GLILLWDVDG 420
  421 GLTMIDKYLY STDDNIKSGA LLACGIVNCG IRNEVDPAHA LLSDYIDNQN SCMRVGAILG 480
  481 LGIAYAGSNR SIVIDTLKTV FSFGSNNKSS ASVEILGITA LSLGLISVGS CNSEITEILL 540
  541 QTIMGLTKAD LKDTYTRFLF LGLGLLYLGR QKSTEAVMMT LEVLEEPYRS MATTMVDICA 600
  601 YAGTGNVLKI QQLLHICSDH YETSSADDEK EKSKKDKGKD KEKEKEKEKE KEREKDLSAT 660
  661 QSIAVLGIAL IAMGEDIGAE MAYRSFGNLL RYCEPAIRRA VPLALGLISA SNPKLNIIDT 720
  721 LSKFSHDSDA EVAHNAIFAM GLVGAGTNNA RLASMLRQLA QYHSKDPSNL FMVRIAQSLT 780
  781 HLGKGTLSLS PYHSDRQLMN PMAVAGLMAT LVSLLDVKNL ILNRSHYLLY TLVPAMQARM 840
  841 LITFDEELNQ LQVPVRVGIA IDVVGQAGKP KTITGFQTHT TPVLLAIGER AELATDEYLA 900
  901 LTPVMEGFVI LKKNPNFVK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.56

Protein Overview: Rpn1-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: