Protein Overview: Eip74EF-PA

General Information:
Name(s) found:	Eip74EF-PA / FBpp0074965 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|84942\|pir\|\|A34692 ecdysone-induced protein E74A - fruit fly (Drosophila melanogaster) [NCBI NR] gi\|45644950\|sp\|P20105.2\|E74EA_DROME RecName: Full=Ecdysone-induced protein 74EF isoform A; AltName: Full=ETS-related protein E74A [NCBI NR] ref\|NP_730286.2\| CG32180-PC [Drosophila melanogaster] [NCBI NR] gi\|24666012\|ref\|NP_730287.1\| Ecdysone-induced protein 74EF, isoform A [Drosophila melanogaster] [NCBI NR] gi\|23093231\|gb\|AAF49323.2\| Ecdysone-induced protein 74EF, isoform A [Drosophila melanogaster] [NCBI NR] gi\|157308\|gb\|AAA28493.1\| E74A protein [NCBI NR] Ecdysone-induced protein 74EF isoform A OS=Drosophila melanogaster GN=Eip74EF PE=2 SV=2 [Swiss-Prot] (P20105) Ecdysone-induced protein 74EF isoform A (ETS-related protein E74A) [Swiss-Prot] The gene Ecdysone-induced protein 74EF is referred to in FlyBase by the symbol Dmel\Eip74EF (CG32180, FBgn0000567). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17553258..17612407. It has the cytological map location 74D4-74E2. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: cellular process; autophagy; salivary gland cell autophagic cell death. 42 alleles are reported. The phenotypes of these alleles are annotated with: larva; salivary gland; adult epidermis; cuticle; air bubble; procephalic segment; anterior pupal spiracle. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] >CG32180-PA translation from_gene[CG32180 Eip74EF FBgn0000567] seq_release:3 mol_weight=87139 cds_boundaries:(3L:17,510,652..17,547,786[-]) aa_length:829 transcript_info:[CG32180-RA seq_release:3] gene_info:[gene symbol:Eip74EF synonyms:[CG6285 CG6273] [hmr_yeast5_DM3-1_pombe.fasta] CG32180-PA, isoform A [Drosophila melanogaster]gi\|24666012\|ref\|NP_730287.1\| CG32180-PA [Drosophila melanogaster]gi\|45551585\|ref\|NP_730286.2\| CG32180-PC [Drosophila melanogaster]gi\|84942\|pir\|\|A34692 ecdysone-induced protein E74A - fruit fly (Drosophila [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17590560..17591067,17591287..17591568,17591921..17592007); ID=FBpp0074965; name=Eip74EF-PA; parent=FBgn0000567,FBtr0075202; dbxref=FlyBase_Annotation_IDs:CG32180-PA,F [fly-100309-contam.fasta] ecdysone-induced protein E74A - fruit fly (Drosophila melanogaster) [nr-271106-contam.fasta] Ecdysone-induced protein 74EF CG32180-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Ecdysone-induced protein 74EF isoform A (ETS-related protein E74A) [nr-271106-contam.fasta] E74A protein [nr-271106-contam.fasta] CG32180-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17590560..17591067,17591287..17591568,17591921..17592007); ID=FBpp0074965; name=Eip74EF-PA; parent=FBgn0000567,FBtr0075202; dbxref=FlyBase_Annotation_IDs:CG32180-PA,FlyBase:FBpp0074965,GB_protein:AAF49323.2,REFSEQ:NP_730287,GB_protein:AAF49323; MD5=29170c8397ca11d0be367beaee610027; length=829; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17590560..17591067,17591287..17591568,17591921..17592007); ID=FBpp0074965; name=Eip74EF-PA; parent=FBgn0000567,FBtr0075202; dbxref=FlyBase_Annotation_IDs:CG32180-PA,FlyBase:FBpp0074965,GB_protein:AAF49323.2,REFSEQ:NP_730287,GB_protein:AAF49323; MD5=29170c8397ca11d0be367beaee610027; length=829; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17590560..17591067,17591287..17591568,17591921..17592007); ID=FBpp0074965; name=Eip74EF-PA; parent=FBgn0000567,FBtr0075202; dbxref=FlyBase_Annotation_IDs:CG32180-PA,FlyBase:FBpp0074965,GB_protein:AAF49323.2,REFSEQ:NP_730287,GB_protein:AAF49323,FlyMine:FBpp0074965,modMine:FBpp0074965; MD5=29170c8397ca11d0be367beaee610027; length=829; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:complement(join(17598821..17598907,17598187..17598468,17597460..17597967,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0074965; name=Eip74EF-PA; parent=FBgn0000567,FBtr0075202; dbxref=FlyBase_Annotation_IDs:CG32180-PA,FlyBase:FBpp0074965,GB_protein:AAF49323.2,REFSEQ:NP_730287,GB_protein:AAF49323,FlyMine:FBpp0074965,modMine:FBpp0074965; MD5=29170c8397ca11d0be367beaee610027; length=829; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(17598821..17598907,17598187..17598468,17597460..17597967,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0074965; name=Eip74EF-PA; parent=FBgn0000567,FBtr0075202; dbxref=FlyBase_Annotation_IDs:CG32180-PA,FlyBase:FBpp0074965,GB_protein:AAF49323.2,REFSEQ:NP_730287,GB_protein:AAF49323,FlyMine:FBpp0074965,modMine:FBpp0074965; MD5=29170c8397ca11d0be367beaee610027; length=829; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of P11536, Ecdysone-induced protein 74EF isoform A OS=Drosophila melanogaster GN=Eip74EF PE=2 SV=2 [DROME.fasta.20160308] FBpp0074965 type=protein; loc=3L:complement(join(17598821..17598907,17598187..17598468,17597460..17597967,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0074965; name=Eip74EF-PA; parent=FBgn0000567,FBtr0075202; dbxref=FlyBase_Annotation_IDs:CG32180-PA,FlyBase:FBpp0074965,GB_protein:AAF49323.2,REFSEQ:NP_730287,GB_protein:AAF49323,FlyMine:FBpp0074965,modMine:FBpp0074965; MD5=29170c8397ca11d0be367beaee610027; length=829; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:complement(join(17598821..17598907,17598187..17598468,17597460..17597967,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0074965; name=Eip74EF-PA; parent=FBgn0000567,FBtr0075202; dbxref=FlyBase_Annotation_IDs:CG32180-PA,FlyBase:FBpp0074965,GB_protein:AAF49323.2,REFSEQ:NP_730287,GB_protein:AAF49323,UniProt/Swiss-Prot:P20105,FlyMine:FBpp0074965,modMine:FBpp0074965; MD5=29170c8397ca11d0be367beaee610027; length=829; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	829 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS][NAS]
Biological Process:	cell death [TAS] regulation of development, heterochronic [TAS] oogenesis [NAS] autophagy [IMP] regulation of transcription, DNA-dependent [IEA][ISS] salivary gland cell autophagic cell death [IMP][NAS] regulation of transcription [NAS] cellular process [IMP]
Molecular Function:	transcription factor activity [IEA][TAS] specific RNA polymerase II transcription factor activity [ISS] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPFIDDALLW CPDNDGRLVG GLDLGTCIAD DSTANGTENL NPSIQSAGNP NNPQQSVGGE  60
   61 ILGSVESAGN ELNGAAARNV NVVVEPLCGG DSSDELFRSF SESNFEIESL LSDLATVEVK 120
  121 VENEENNNNV ITDDDFASVA AAVVANDDLL AKENAQLSAQ GLVDSVAASL ADSGDAGGQQ 180
  181 ALLAFGSSSS AASAIAAAAA ALCGDLINNN NNNSNSNNNS NGNGNHGGGG GGASSGGGVA 240
  241 GDCATKLEYA LMGGQPLAEE PRFVTSAAAN PLLVEKLMSK CLNIEKRMDK LSDTEIPIVK 300
  301 QSTSPAPQQQ LQQQHHLQQQ QQQQPHNGST FAGATALLHI KTEQNTLLTP LQLQQQQQQQ 360
  361 QGLHGAAGNG GSSNGNNAHQ QQQPLAIPQR PLLHNLLSGG AIHNPHHRNY TTATTGSFPP 420
  421 SPADSGVSDV DSSSSGGQPC ADELKARLGM PPATSASAAA AAAAAAAAAA HLHTGTFLHP 480
  481 NLYQNNAANS LRNIWNRSVG VPDNYYGSSG AGSGGTQPGG PGNPQTPGYL TTSYFNAPTA 540
  541 ATAAASQRGT TINGYHSLHQ QQQQQQQSQQ SQQQQQLAHQ QLSHQQQQAL HQQLSHQQQQ 600
  601 QQQQQQQHPH SQLNGPHPHS HPHSHPHSHP HAGQHTHSTI AAAAAAAAAS VVSSSSSAVA 660
  661 AAAMLSASAA AAATAAAAAG GSQSVIQPAT SSVSYDLSYM LELGGFQQRK AKKPRKPKLE 720
  721 MGVKRRSREG STTYLWEFLL KLLQDREYCP RFIKWTNREK GVFKLVDSKA VSRLWGMHKN 780
  781 KPDMNYETMG RALRYYYQRG ILAKVDGQRL VYQFVDVPKD IIEIDCNGV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Eip74EF-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: