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Protein Overview: Sod-PA

General Information:
Name(s) found: Sod-PA / FBpp0075958 [FlyBase]
Description(s) found:
Found 30 descriptions.
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  • The gene Superoxide dismutase is referred to in FlyBase by the symbol Dmel\Sod (CG11793, FBgn0003462). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:11105381..11106838. It has the cytological map location 68A7. It is reported to have molecular function</span>: antioxidant activity; superoxide dismutase activity. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan; response to oxidative stress. 29 alleles are reported. The phenotypes of these alleles are annotated with: primary pigment cell; photoreceptor cell; secondary pigment cell; adult brain. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 153 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [NAS]
    Biological Process: response to oxidative stress [IMP]
    superoxide metabolic process [IEA][NAS]
    removal of superoxide radicals [NAS]
    determination of adult lifespan [IMP][TAS]
    oxidation reduction [IEA]
    aging [TAS]
    Molecular Function: antioxidant activity [NAS]
    metal ion binding [IEA]
    superoxide dismutase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVKAVCVIN GDAKGTVFFE QESSGTPVKV SGEVCGLAKG LHGFHVHEFG DNTNGCMSSG  60
   61 PHFNPYGKEH GAPVDENRHL GDLGNIEATG DCPTKVNITD SKITLFGADS IIGRTVVVHA 120
  121 DADDLGQGGH ELSKSTGNAG ARIGCGVIGI AKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] PSI-BLAST 51.045757 Cu,Zn superoxide dismutase, SOD

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein phosphatase 2B binding
    		•  13.5719110466797 bayes_pls_golite062009
  • superoxide dismutase activity
    		•  12.1093323949609 bayes_pls_golite062009
  • oxidoreductase activity, acting on superoxide radicals as acceptor
    		•  12.1093323949609 bayes_pls_golite062009
  • chaperone binding
    		•  5.11696266714142 bayes_pls_golite062009
  • superoxide dismutase copper chaperone activity
    		•  4.90125496493753 bayes_pls_golite062009
  • copper ion binding
    		•  4.51765925795625 bayes_pls_golite062009
  • protein phosphatase binding
    		•  3.26481550276071 bayes_pls_golite062009
  • phosphatase binding
    		•  3.1414149853516 bayes_pls_golite062009
  • transition metal ion binding
    		•  2.451533032488 bayes_pls_golite062009
  • binding
    		•  2.28211284921339 bayes_pls_golite062009
  • protein binding
    		•  1.96660745768497 bayes_pls_golite062009
  • enzyme binding
    		•  1.82618630359051 bayes_pls_golite062009
  • cation binding
    		•  1.79413011653575 bayes_pls_golite062009
  • metal ion binding
    		•  1.79413011653575 bayes_pls_golite062009
  • ion binding
    		•  1.78699219376941 bayes_pls_golite062009
  • catalytic activity
    		•  1.09233965765942 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  0.658369569046781 bayes_pls_golite062009
  • metallochaperone activity
    		•  0.515959593535099 bayes_pls_golite062009
  • copper chaperone activity
    		•  0.412497194733789 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.32642292951469 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.262312399748454 bayes_pls_golite062009
  • zinc ion binding
    		•  0.25600715352161 bayes_pls_golite062009
  • antioxidant activity
    		•  0.240491838042064 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle