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Protein Overview: CG17030-PA

General Information:
Name(s) found: CG17030-PA / FBpp0073230 [FlyBase]
Description(s) found:
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  • gi|7292552|gb|AAF47953.1| CG17030 [Drosophila melanogaster] [NCBI NR]
  • gi|21355413|ref|NP_647941.1| CG17030 [Drosophila melanogaster] [NCBI NR]
  • gi|19528135|gb|AAL90182.1| AT26201p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG17030 (CG17030, FBgn0035584). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4979981..4980769. It has the cytological map location 64C4. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: post-translational protein modification; regulation of protein metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG17030-PA translation from_gene[CG17030 CG17030 FBgn0035584] seq_release:3 mol_weight=21335 cds_boundaries:(3L:4,958,039..4,958,578[-]) aa_length:180 transcript_info:[CG17030-RA seq_release:3] gene_info:[gene symbol:CG17030 FBgn0035584 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VZ73) CG17030 protein (EC 6.3.2.19) (AT26201p) (Ubiquitin-conjugating enzyme E2) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) [DrosMelano7227.FASTAC.txt]
  • (AE003483) CG17030 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG17030-PA [Drosophila melanogaster]gi|19528135|gb|AAL90182.1| AT26201p [Drosophila melanogaster]gi|21355413|ref|NP_647941.1| CG17030-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:complement(4980095..4980637); ID=FBpp0073230; name=CG17030-PA; parent=FBgn0035584,FBtr0073374; dbxref=FlyBase:FBpp0073230,FlyBase_Annotation_IDs:CG17030-PA,GB_protein:AAF47953.1,REFSEQ:NP_647941,GB_protein:AAF47953; MD5=bf4e708022af98 [fly-100309-contam.fasta]
  • CG17030-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • AT26201p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:complement(4980095..4980637); ID=FBpp0073230; name=CG17030-PA; parent=FBgn0035584,FBtr0073374; dbxref=FlyBase:FBpp0073230,FlyBase_Annotation_IDs:CG17030-PA,GB_protein:AAF47953.1,REFSEQ:NP_647941,GB_protein:AAF47953; MD5=bf4e708022af98c866555da3f7753e53; length=180; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:complement(4980095..4980637); ID=FBpp0073230; name=CG17030-PA; parent=FBgn0035584,FBtr0073374; dbxref=FlyBase:FBpp0073230,FlyBase_Annotation_IDs:CG17030-PA,GB_protein:AAF47953.1,REFSEQ:NP_647941,GB_protein:AAF47953; MD5=bf4e708022af98c866555da3f7753e53; length=180; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • AT26201p OS=Drosophila melanogaster GN=CG17030 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:complement(4980095..4980637); ID=FBpp0073230; name=CG17030-PA; parent=FBgn0035584,FBtr0073374; dbxref=FlyBase:FBpp0073230,FlyBase_Annotation_IDs:CG17030-PA,GB_protein:AAF47953.1,REFSEQ:NP_647941,GB_protein:AAF47953,FlyMine:FBpp0073230,modMine:FBpp0073230; MD5=bf4e708022af98c866555da3f7753e53; length=180; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • AT26201p OS=Drosophila melanogaster GN=CG17030 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=3L:complement(4980095..4980637); ID=FBpp0073230; name=CG17030-PA; parent=FBgn0035584,FBtr0073374; dbxref=FlyBase:FBpp0073230,FlyBase_Annotation_IDs:CG17030-PA,GB_protein:AAF47953.1,REFSEQ:NP_647941,GB_protein:AAF47953,FlyMine:FBpp0073230,modMine:FBpp0073230; MD5=bf4e708022af98c866555da3f7753e53; length=180; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:complement(4980095..4980637); ID=FBpp0073230; name=CG17030-PA; parent=FBgn0035584,FBtr0073374; dbxref=FlyBase:FBpp0073230,FlyBase_Annotation_IDs:CG17030-PA,GB_protein:AAF47953.1,REFSEQ:NP_647941,GB_protein:AAF47953,FlyMine:FBpp0073230,modMine:FBpp0073230; MD5=bf4e708022af98c866555da3f7753e53; length=180; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0073230 type=protein; loc=3L:complement(4980095..4980637); ID=FBpp0073230; name=CG17030-PA; parent=FBgn0035584,FBtr0073374; dbxref=FlyBase:FBpp0073230,FlyBase_Annotation_IDs:CG17030-PA,GB_protein:AAF47953.1,REFSEQ:NP_647941,GB_protein:AAF47953,FlyMine:FBpp0073230,modMine:FBpp0073230; MD5=bf4e708022af98c866555da3f7753e53; length=180; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:complement(4980095..4980637); ID=FBpp0073230; name=CG17030-PA; parent=FBgn0035584,FBtr0073374; dbxref=FlyBase:FBpp0073230,FlyBase_Annotation_IDs:CG17030-PA,GB_protein:AAF47953.1,REFSEQ:NP_647941,GB_protein:AAF47953,UniProt/TrEMBL:Q9VZ73,FlyMine:FBpp0073230,modMine:FBpp0073230; MD5=bf4e708022af98c866555da3f7753e53; length=180; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 180 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of protein metabolic process [IEA]
    post-translational protein modification [IEA]
    Molecular Function: ubiquitin-protein ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKEEPLMD GPKRMNRELA LMLEDKQNLQ FRNLLVEPNN IYKWTGLLMP VAPPYDKGAY  60
   61 KMEIDFPLDY PFKPPRIHIN TRMYHLNVNE RGQVCVPILE VEHWIPTTRI DQVLQVLLAT 120
  121 INDPQPENAW HIEMAGEYRN DPVRFFKMAD AWVQKYSEPR PTEEELAKFA RKRKKAMTKK 180
  181

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..180] PSI-BLAST 39.0 Ubiquitin conjugating enzyme, UBC

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  11.3486134076304 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  11.2964721480824 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  10.2401422444624 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  8.93602533934698 bayes_pls_golite062009
  • ligase activity
    		•  5.17219147802758 bayes_pls_golite062009
  • ISG15 ligase activity
    		•  2.94474247095323 bayes_pls_golite062009
  • binding
    		•  1.75350658654805 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.46828741962969 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.42147247383136 bayes_pls_golite062009
  • DNA binding
    		•  1.31679667558286 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.905654666464382 bayes_pls_golite062009
  • catalytic activity
    		•  0.891402822028799 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.843488104298821 bayes_pls_golite062009
  • protein binding
    		•  0.726328463755484 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  0.715654744941217 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.58835335751383 bayes_pls_golite062009
  • kinase activity
    		•  0.519703305315987 bayes_pls_golite062009
  • protein kinase activity
    		•  0.443948654247666 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.373779304908933 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.182854082413338 bayes_pls_golite062009
  • transferase activity
    		•  0.0984525836903841 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle