Protein Overview: Rpd3-PA

General Information:
Name(s) found:	Rpd3-PA / FBpp0073173 [FlyBase]
Description(s) found: Found 23 descriptions. SHOW ALL	The gene Rpd3 is referred to in FlyBase by the symbol Dmel\Rpd3 (CG7471, FBgn0015805). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4626717..4629467. It has the cytological map location 64B12. There is experimental evidence that it has the molecular function</span>: protein binding; histone deacetylase activity. There is experimental evidence that it is involved in the biological process</span>: blastoderm segmentation; gene silencing; histone deacetylation; negative regulation of transcription; determination of adult lifespan; dendrite morphogenesis; muscle organ development; regulation of transcription; chromatin silencing. 30 alleles are reported. The phenotypes of these alleles are annotated with: macrochaeta; sex comb; alula; wing; ommatidium. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	521 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][NAS] Sin3 complex [NAS] NuRD complex [IPI][NAS] ESC/E(Z) complex [IDA][TAS] Myb complex [IDA] chromatin [IDA]
Biological Process:	gene silencing [IMP] muscle organ development [IMP] oogenesis [TAS] negative regulation of transcription [IEP][NAS] determination of adult lifespan [IMP][TAS] blastoderm segmentation [IMP] chromatin silencing [IGI][IMP][IPI] histone deacetylation [IMP][NAS] regulation of transcription [IDA] dendrite morphogenesis [IMP]
Molecular Function:	protein binding [IPI] histone deacetylase activity [IDA][ISS][NAS] transcription corepressor activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSHSKKRVC YYYDSDIGNY YYGQGHPMKP HRIRMTHNLL LNYGLYRKME IYRPHKATAD  60
   61 EMTKFHSDEY VRFLRSIRPD NMSEYNKQMQ RFNVGEDCPV FDGLYEFCQL SAGGSVAAAV 120
  121 KLNKQASEIC INWGGGLHHA KKSEASGFCY VNDIVLGILE LLKYHQRVLY IDIDVHHGDG 180
  181 VEEAFYTTDR VMTVSFHKYG EYFPGTGDLR DIGAGKGKYY AVNIPLRDGM DDDAYESIFV 240
  241 PIISKVMETF QPAAVVLQCG ADSLTGDRLG CFNLTVKGHG KCVEFVKKYN LPFLMVGGGG 300
  301 YTIRNVSRCW TYETSVALAV EIANELPYND YFEYFGPDFK LHISPSNMTN QNTSEYLEKI 360
  361 KNRLFENLRM LPHAPGVQIQ AIPEDAINDE SDDEDKVDKD DRLPQSDKDK RIVPENEYSD 420
  421 SEDEGEGGRR DNRSYKGQRK RPRLDKDTNS NKASSETSSE IKDEKEKGDG ADGEESTASN 480
  481 TNSNNNSNNK SDNDAGATAN AGSGSGSGSG AGAKGAKENN I

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: Rpd3-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: