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Protein Overview: scramb2-PA

General Information:
Name(s) found: scramb2-PA / FBpp0072875 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene scramblase 2 is referred to in FlyBase by the symbol Dmel\scramb2 (CG1893, FBgn0035390). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:3044105..3046810. It has the cytological map location 63A3. Based on sequence similarity, it is predicted to have molecular function</span>: phospholipid scramblase activity. There is experimental evidence that it is involved in the biological process</span>: synaptic transmission. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 263 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: phospholipid scrambling [ISS]
    synaptic transmission [IMP]
    Molecular Function: phospholipid scramblase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMQMSEYKVL PQNAPQDENG AVVLQPQAAN VGNNANGPEN WMSIPVGMPN CPQGLEYLTA  60
   61 LDQLLVSQKI EKLELLTGFE TKNRFKVKNS LGQNVYFAYE ESDCCTRNML GRSRPFEMKI 120
  121 LDNFQNEVLH LYRPFKCDIL CCFPSCMNAV EVSAPPGQVI GSVEQVCTFM RPKFNIKNTC 180
  181 GDTVLQIEGP VCPCKCFSDT NFKVLSANNE EIGKISKQWS GLGRELFTDA DYFSVTFPLN 240
  241 LDVRMKALIF AALFLIDAVY YEQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..263] FFAS03 3.32 X-ray structure of protein from arabidopsis thaliana AT5G01750

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • signal transducer activity
    		•  1.40960604634475 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.40960604634475 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.20555655112374 bayes_pls_golite062009
  • receptor activity
    		•  1.15270506651032 bayes_pls_golite062009
  • binding
    		•  1.05855974212836 bayes_pls_golite062009
  • G-protein coupled photoreceptor activity
    		•  0.94252200727689 bayes_pls_golite062009
  • protein binding
    		•  0.6155304260359 bayes_pls_golite062009
  • photoreceptor activity
    		•  0.504277760871571 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  0.450513229504489 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle