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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. The process by which all major lipid classes are redistributed within the plasma membrane following cell activation or injury, resulting in surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE). Cell surface-exposed PS can serve as receptor sites for coagulation enzyme complexes, and contributes to cell clearance by the reticuloendothelial system. A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: phospholipid scrambling
Acc: GO:0017121
Aspect: Biological Process
Desc: The process by which all major lipid classes are redistributed within the plasma membrane following cell activation or injury, resulting in surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE). Cell surface-exposed PS can serve as receptor sites for coagulation enzyme complexes, and contributes to cell clearance by the reticuloendothelial system.
Synonyms:
  • PL scrambling
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0017121 - phospholipid scrambling (interactive image map)

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