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View Structure Prediction Details

Protein: scramb2-PA
Organism: Drosophila melanogaster
Length: 263 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for scramb2-PA.

Description E-value Query
Range
Subject
Range
PLS1_RAT - Phospholipid scramblase 1 OS=Rattus norvegicus GN=Plscr1 PE=1 SV=1
372.0 [0..9] [263..70]
PLS2_BOVIN - Phospholipid scramblase 2 OS=Bos taurus GN=PLSCR2 PE=2 SV=1
364.0 [0..4] [262..30]
gi|62471433 - gi|62471433|gb|AAH93497.1| Plscr1 protein [Mus musculus]
358.0 [0..22] [263..82]
gi|119599335 - gi|119599335|gb|EAW78929.1| phospholipid scramblase 1, isoform CRA_g [Homo sapiens]
gi|114589691, gi... - gi|114589693|ref|XP_516804.2| PREDICTED: similar to hMmTRA1b isoform 4 [Pan troglodytes], gi|1145896...
357.0 [0..4] [262..36]
gi|123979952, gi... - gi|123994715|gb|ABM84959.1| phospholipid scramblase 1 [synthetic construct], gi|123979952|gb|ABM8180...
PLSCR1 - phospholipid scramblase 1
357.0 [0..4] [262..43]

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Predicted Domain #1
Region A:
Residues: [1-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMQMSEYKVL PQNAPQDENG AVVLQPQAAN VGNNANGPEN WMSIPVGMPN CPQGLEYLTA  60
   61 LDQLLVSQKI EKLELLTGFE TKNRFKVKNS LGQNVYFAYE ESDCCTRNML GRSRPFEMKI 120
  121 LDNFQNEVLH LYRPFKCDIL CCFPSCMNAV EVSAPPGQVI GSVEQVCTFM RPKFNIKNTC 180
  181 GDTVLQIEGP VCPCKCFSDT NFKVLSANNE EIGKISKQWS GLGRELFTDA DYFSVTFPLN 240
  241 LDVRMKALIF AALFLIDAVY YEQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.32
Match: 1zxuA
Description: X-ray structure of protein from arabidopsis thaliana AT5G01750
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
signal transducer activity 1.40960604634475 bayes_pls_golite062009
molecular transducer activity 1.40960604634475 bayes_pls_golite062009
transmembrane receptor activity 1.20555655112374 bayes_pls_golite062009
receptor activity 1.15270506651032 bayes_pls_golite062009
binding 1.05855974212836 bayes_pls_golite062009
G-protein coupled photoreceptor activity 0.94252200727689 bayes_pls_golite062009
protein binding 0.6155304260359 bayes_pls_golite062009
photoreceptor activity 0.504277760871571 bayes_pls_golite062009
G-protein coupled receptor activity 0.450513229504489 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle