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Protein Overview: Sox14-PB, Sox14-...

General Information:
Name(s) found: FBpp0309947 [FlyBase]
Sox14-PB / FBpp0072067 [FlyBase]
Sox14-PA / FBpp0072066 [FlyBase]
Description(s) found:
Found 40 descriptions.
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  • type=protein; loc=2R:join(19867735..19868268,19871067..19872542); ID=FBpp0309947; name=Sox14-PC; parent=FBgn0005612,FBtr0343282; dbxref=FlyBase:FBpp0309947,FlyBase_Annotation_IDs:CG3090-PC; MD5=777389ede04f22b78fffd4a82f24eca9; length=669; release=r5.56; species=Dmel; [FlyBase]
  • The gene Sox box protein 14 is referred to in FlyBase by the symbol Dmel\Sox14 (CG3090, FBgn0005612). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19866744..19872700. It has the cytological map location 60A16. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of transcription. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Sox box protein 14 is referred to in FlyBase by the symbol Dmel\Sox14 (CG3090, FBgn0005612). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19866744..19872700. It has the cytological map location 60A16. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of transcription. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 669 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS][NAS]
    Biological Process: regulation of transcription [ISS]
    neuron remodeling [IGI]
    dendrite morphogenesis [IGI]
    Molecular Function: transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIAKPNQATT EPPLSLRPGT VPTVPATTPA RPATITIQRR HPAPKADSTP HTLPPFSPSP  60
   61 SPASSPSPAP AQTPGAQKTQ SQAAITHPAA VASPSAPVAA AAPKTPKTPE PRSTHTHTHT 120
  121 HSQHFSPPPR ESEMDGERSP SHSGHEMTLS MDGIDSSLVF GSARVPVNSS TPYSDATRTK 180
  181 KHSPGHIKRP MNAFMVWSQM ERRKICERTP DLHNAEISKE LGRRWQLLSK DDKQPYIIEA 240
  241 EKLRKLHMIE YPNYKYRPQK KQTRSPGSLK PNQDADGCEA RNDTTNNNNS LTTLAINGTT 300
  301 TAGRKSKRST STCQSGSASK RLRNDSGDTS SKPKYEVKME SAEQLNSADI ILPSADNLIS 360
  361 YQSSEYLPLS TLSNADCDEK LHSELSSGPL ESRENLSEVV NRFLPLFLGG NEDSQLGVSS 420
  421 LTQSQHNQSD PTAGLMDNIS DISPINDREE LTEEVMRYLP YLEVNPSSDG LTLKVESSSL 480
  481 LGKPLNEPVF DSEDNIVNDA NLHSASHQIP PYVPDSHDCF AEDCGGDSSS HQVEFEVVRP 540
  541 QTVTMTMTCT LPYGGPDAGH TTFQADDFNA IPSAAEDSEC SILTTSNSPQ IGFNGSSFVE 600
  601 ADAIGSTCTY AQQDYTGSVI ETHNDLNYAA HDNNGALLAY TFEDLPPQPT GSHLEFNTNK 660
  661 YEFASYYKM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..179] FFAS03 1.47 No description for 2j63A was found.
    2 View Details [180..298] PSI-BLAST 19.0 No description for 2gzkA was found.
    3 View Details [299..443] deduced N/A No confident structure predictions are available.
    4 View Details [444..493] deduced N/A No confident structure predictions are available.
    5 View Details [494..559] deduced N/A No confident structure predictions are available.
    6 View Details [560..669] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • DNA binding
    		•  5.15324651287773 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.9607192917135 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.70730250099648 bayes_pls_golite062009
  • transcription factor activity
    		•  3.82658263870186 bayes_pls_golite062009
  • binding
    		•  3.6211482127468 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.96229555092695 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.84606709725198 bayes_pls_golite062009
  • transcription activator activity
    		•  1.62744929149746 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.53825678633232 bayes_pls_golite062009
  • protein binding
    		•  1.131658134984 bayes_pls_golite062009
  • transcription factor binding
    		•  1.10315330167937 bayes_pls_golite062009
  • DNA bending activity
    		•  0.87985209274756 bayes_pls_golite062009
  • chromatin binding
    		•  0.830960835937769 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle