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Protein Overview: CG5594-PC

General Information:
Name(s) found: CG5594-PC / FBpp0072048 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG5594 (CG5594, FBgn0025698). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19795651..19812619. It has the cytological map location 60A9-60A11. Based on sequence similarity, it is predicted to have molecular function</span>: amino acid transmembrane transporter activity; potassium:chloride symporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: amino acid transport; transport. 8 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1059 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISS]
    Biological Process: mechanosensory behavior [IMP]
    sodium ion transport [IEA]
    transmembrane transport [IEA]
    transport [ISS]
    chloride transport [IEA]
    amino acid transport [ISS]
    response to mechanical stimulus [IMP]
    Molecular Function: potassium:chloride symporter activity [ISS]
    amino acid transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSNSAKDDS DEMEIIPSEH NGTVHETKNE DSGDIHRAEE NQKSSIDPNL YLYDDDLETR  60
   61 PHISTFISSI ANYENTIPAA TDPDAKPAAP SARMGTLIGV FLPCIQNIFG VILFIRLTWV 120
  121 VGTAGAVCGF LIVLTCCCVT MLTAISMSAI ATNGVVPAGG SYFMISRSLG PEFGGAVGML 180
  181 FYTGTTLAAA MYIVGAVEIV LTYMAPWASI FGDFTKDADA MYNNFRVYGT LLLIFMGLIV 240
  241 FLGVKFVNKF ATVALACVIL SIIAVYVGIF DNIHGNEKLY MCVLGKRLLK DIPLENCTKE 300
  301 DSFLRDIYCP DGKCEEYYLA NNVTKVKGIK GLASGVFYDN IFPSFLEKGQ FISYGKSAID 360
  361 IENTSGESYN QIMADITTSF TLLIGIFFPS VTGIMAGSNR SGDLADAQKS IPIGTICAIL 420
  421 TTSTVYLSSV MFFAGTVDNL LLRDKFGQSI GGKLVVANIA WPNQWVILIG SFLSTLGAGL 480
  481 QSLTGAPRLL QAIARDEIIP FLAPFAKSSK RGEPTRALLL TIVICQCGIL LGNVDLLAPL 540
  541 LSMFFLMCYG FVNLACAVQT LLRTPNWRPR FKFYHWSLSL IGLTLCISVM IMTSWYFALI 600
  601 AMGMAIIIYK YIEYRGAEKE WGDGIRGMAL TAARYSLLRL EEGPPHTKNW RPQILVLSKL 660
  661 NDNLLPKYRK IFSFATQLKA GKGLTICVSV IKGDHTKITN KAVDAKATLR KYMTDEKVKG 720
  721 FCDVLVAQQI GEGLSSVIQT IGLGGMKPNT VIIGWPYSWR QEGRNSWKTF IQTVRTVAAC 780
  781 HMALMVPKGI NFYPESNHKI GGNIDIWWIV HDGGLLMLLP FLLKQHRTWR NCKLRIFTVA 840
  841 QIEDNSIQMK KDLKTFLYHL RIEADVEVVE MNNSDISAYT YERTLMMEQR NQMLRALGLN 900
  901 KKENSKVVQT IVDHHYDATK TASKVRFADP TIEETQHHDS QNDEKRNSID LDGPENADTP 960
  961 ETTSNKDEST EKADGDFKSS VKPDEFNVRR MHTAIKLNEV IVEKSQDAQL VIMNLPGPPR1020
 1021 EVRAERERNY MEFLEVLTEG LEKVLMVRGG GREVITIYS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..94] deduced N/A No confident structure predictions are available.
    2 View Details [95..568] PSI-BLAST 4.0 Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
    3 View Details [569..650] deduced N/A No confident structure predictions are available.
    4 View Details [651..872] MSA 1.228962 View MSA. No confident structure predictions are available.
    5 View Details [873..1059] MSA 2.099976 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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