Protein Overview: CG5594-PB

General Information:
Name(s) found:	CG5594-PB / FBpp0072047 [FlyBase]
Description(s) found: Found 20 descriptions. SHOW ALL	This gene is referred to in FlyBase by the symbol Dmel\CG5594 (CG5594, FBgn0025698). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19795651..19812619. It has the cytological map location 60A9-60A11. Based on sequence similarity, it is predicted to have molecular function</span>: amino acid transmembrane transporter activity; potassium:chloride symporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: amino acid transport; transport. 8 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1028 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [ISS]
Biological Process:	mechanosensory behavior [IMP] sodium ion transport [IEA] transmembrane transport [IEA] transport [ISS] chloride transport [IEA] amino acid transport [ISS] response to mechanical stimulus [IMP]
Molecular Function:	potassium:chloride symporter activity [ISS] amino acid transmembrane transporter activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSNSAKDDS DEMEIIPSEH NGTVHETKNE DSGDIHRAEE NQKSSIDPNL YLYDDDLETR  60
   61 PHISTFISSI ANYENTIPAA TDPDAKPAAP SARMGTLIGV FLPCIQNIFG VILFIRLTWV 120
  121 VGTAGAVCGF LIVLTCCCVT MLTAISMSAI ATNGVVPAGG SYFMISRSLG PEFGGAVGML 180
  181 FYTGTTLAAA MYIVGAVEIV LTYMAPWASI FGDFTKDADA MYNNFRVYGT LLLIFMGLIV 240
  241 FLGVKFVNKF ATVALACVIL SIIAVYVGIF DNIHGNEKLY MCVLGKRLLK DIPLENCTKE 300
  301 DSFLRDIYCP DGKCEEYYLA NNVTKVKGIK GLASGVFYDN IFPSFLEKGQ FISYGKSAID 360
  361 IENTSGESYN QIMADITTSF TLLIGIFFPS VTGIMAGSNR SGDLADAQKS IPIGTICAIL 420
  421 TTSTVYLSSV MFFAGTVDNL LLRDKFGQSI GGKLVVANIA WPNQWVILIG SFLSTLGAGL 480
  481 QSLTGAPRLL QAIARDEIIP FLAPFAKSSK RGEPTRALLL TIVICQCGIL LGNVDLLAPL 540
  541 LSMFFLMCYG FVNLACAVQT LLRTPNWRPR FKFYHWSLSL IGLTLCISVM IMTSWYFALI 600
  601 AMGMAIIIYK YIEYRGAEKE WGDGIRGMAL TAARYSLLRL EEGPPHTKNW RPQILVLSKL 660
  661 NDNLLPKYRK IFSFATQLKA GKGLTICVSV IKGDHTKITN KAVDAKATLR KYMTDEKVKG 720
  721 FCDVLVAQQI GEGLSSVIQT IGLGGMKPNT VIIGWPYSWR QEGRNSWKTF IQTVRTVAAC 780
  781 HMALMVPKGI NFYPESNHKI GGNIDIWWIV HDGGLLMLLP FLLKQHRTWR NCKLRIFTVA 840
  841 QIEDNSIQMK KDLKTFLYHL RIEADVEVVE MNNSDISAYT YERTLMMEQR NQMLRALGLN 900
  901 KKENSKVDSQ NDEKRNSIDL DGPENADTPE TTSNKDESTE KADGDFKSSV KPDEFNVRRM 960
  961 HTAIKLNEVI VEKSQDAQLV IMNLPGPPRE VRAERERNYM EFLEVLTEGL EKVLMVRGGG1020
 1021 REVITIYS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
monovalent inorganic cation transmembrane transporter activity	6.93719418697328	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	6.67949994760371	bayes_pls_golite062009
cation transmembrane transporter activity	6.50939400533716	bayes_pls_golite062009
ion transmembrane transporter activity	6.40081133240949	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	6.02701109829891	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	5.9695962563814	bayes_pls_golite062009
transporter activity	4.2806100513341	bayes_pls_golite062009
transmembrane transporter activity	4.19885907933483	bayes_pls_golite062009
substrate-specific transporter activity	4.09889747645813	bayes_pls_golite062009
binding	1.32681091506724	bayes_pls_golite062009
heme-copper terminal oxidase activity	1.27735515053931	bayes_pls_golite062009
copper ion binding	1.08782819178001	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	0.803860393147327	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	0.803860393147327	bayes_pls_golite062009
cytochrome-c oxidase activity	0.803860393147327	bayes_pls_golite062009
active transmembrane transporter activity	0.349031670056176	bayes_pls_golite062009
primary active transmembrane transporter activity	0.336122020727214	bayes_pls_golite062009
protein binding	0.335149649581279	bayes_pls_golite062009

No functions predicted.

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..93]	deduced	N/A	No confident structure predictions are available.
2	View Details	[94..193]	PSI-BLAST	4.522879	Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
3	View Details	[194..716]	PSI-BLAST	6.045757	Bacterial aa3 type cytochrome c oxidase subunit I
4	View Details	[717..799]	deduced	N/A	No confident structure predictions are available.
5	View Details	[800..941]	MSA	1.130966	View MSA. No confident structure predictions are available.
6	View Details	[942..1028]	MSA	1.080994	View MSA. No confident structure predictions are available.

Protein Overview: CG5594-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: