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Protein Overview: FBpp0310588

General Information:
Name(s) found: FBpp0310588 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • type=protein; loc=2R:join(19564652..19564711,19564772..19564870,19564928..19565176,19565238..19565460,19565525..19565682,19565741..19566011,19566070..19566212); ID=FBpp0310588; name=Pde8-PC; parent=FBgn0266377,FBtr0344176; dbxref=FlyBase:FBpp0310588,FlyBase_Annotation_IDs:CG45019-PC; MD5=95cc4c7051f8c575bb7ead491b39b872; length=400; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 400 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: two-component signal transduction system (phosphorelay) [IEA]
    mesoderm development [IEP]
    regulation of transcription, DNA-dependent [IEA]
    Molecular Function: 3',5'-cyclic-AMP phosphodiesterase activity [IDA][ISS]
    two-component response regulator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEIRTDDPI ATDLIGALLT GPSVYSSRRS SNDSIIRTGS STRTAAIVPA KMKSNPIIME  60
   61 LLDESLSWDF DIFKLEEITD YHPLLYLGME MFRRFDVFAT LNIDENVCKA WLAVIEAHYR 120
  121 KSNTYHNSTH AADVMQATGA FITQLTNKDM LVMDRMEEAT ALIAAAAHDV DHPGRSSAFL 180
  181 CNSNDALAVL YNDLTVLENH HAAITFKLTL GDDKINIFKN LDKETYKSAR STIIDMILAT 240
  241 EMTRHFEHLA KFVSVFGGEE PRDHNPQTDE ETSILMRRML IKVADVSNPA RPMQFCIEWA 300
  301 RRIAEEYFMQ TDEEKQRHLP IVMPMFDRAT CSIPKSQIGF IEYIIQDMMH AWESFIDMPQ 360
  361 LITYMQINYS QWKKYDEQGV NTLAEIMAKQ PPVGKMANSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..400] PSI-BLAST 109.0 Catalytic domain of cyclic nucleotide phosphodiesterase pde4d

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cyclic-nucleotide phosphodiesterase activity
    		•  2.9145758096876 bayes_pls_golite062009
  • 3',5'-cyclic-nucleotide phosphodiesterase activity
    		•  2.80645470666968 bayes_pls_golite062009
  • 3',5'-cyclic-AMP phosphodiesterase activity
    		•  2.4031735631386 bayes_pls_golite062009
  • phosphoric diester hydrolase activity
    		•  2.2478354053668 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.431522480252729 bayes_pls_golite062009
  • binding
    		•  0.0840884387362641 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.0469692618690128 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle