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View Structure Prediction Details

Protein: FBpp0310588
Organism: Drosophila melanogaster
Length: 400 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0310588.

Description E-value Query
Range
Subject
Range
gi|73986145 - gi|73986145|ref|XP_852383.1| PREDICTED: similar to cAMP-specific 3,5-cyclic phosphodiesterase 4C (DP...
447.0 [0..1] [391..426]

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Predicted Domain #1
Region A:
Residues: [1-400]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEIRTDDPI ATDLIGALLT GPSVYSSRRS SNDSIIRTGS STRTAAIVPA KMKSNPIIME  60
   61 LLDESLSWDF DIFKLEEITD YHPLLYLGME MFRRFDVFAT LNIDENVCKA WLAVIEAHYR 120
  121 KSNTYHNSTH AADVMQATGA FITQLTNKDM LVMDRMEEAT ALIAAAAHDV DHPGRSSAFL 180
  181 CNSNDALAVL YNDLTVLENH HAAITFKLTL GDDKINIFKN LDKETYKSAR STIIDMILAT 240
  241 EMTRHFEHLA KFVSVFGGEE PRDHNPQTDE ETSILMRRML IKVADVSNPA RPMQFCIEWA 300
  301 RRIAEEYFMQ TDEEKQRHLP IVMPMFDRAT CSIPKSQIGF IEYIIQDMMH AWESFIDMPQ 360
  361 LITYMQINYS QWKKYDEQGV NTLAEIMAKQ PPVGKMANSK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 109.0
Match: 1oynA
Description: Catalytic domain of cyclic nucleotide phosphodiesterase pde4d
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cyclic-nucleotide phosphodiesterase activity 2.9145758096876 bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity 2.80645470666968 bayes_pls_golite062009
3',5'-cyclic-AMP phosphodiesterase activity 2.4031735631386 bayes_pls_golite062009
phosphoric diester hydrolase activity 2.2478354053668 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.431522480252729 bayes_pls_golite062009
binding 0.0840884387362641 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.0469692618690128 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle