Protein Overview: CG3074-PB, CG3074-PA

General Information:
Name(s) found:	CG3074-PA / FBpp0071698 [FlyBase] CG3074-PB / FBpp0071697 [FlyBase]
Description(s) found: Found 32 descriptions. SHOW ALL	This gene is referred to in FlyBase by the symbol Dmel\CG3074 (CG3074, FBgn0034709). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18077326..18090178. It has the cytological map location 58C7-58D1. Based on sequence similarity, it is predicted to have molecular function</span>: cysteine-type endopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis; immune response. 36 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] This gene is referred to in FlyBase by the symbol Dmel\CG3074 (CG3074, FBgn0034709). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18077326..18090178. It has the cytological map location 58C7-58D1. Based on sequence similarity, it is predicted to have molecular function</span>: cysteine-type endopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis; immune response. 36 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	431 amino acids
Gene Ontology:
Cellular Component:	chorion [IDA]
Biological Process:	immune response [IEA] proteolysis [IEA]
Molecular Function:	cysteine-type endopeptidase activity [ISS] scavenger receptor activity [IEA] polysaccharide binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIKCVHLVG LLVLLMGGAN ALFDHTLKRD FPGPYCAREN TCCKDRHDGC SVPISNTLCY  60
   61 CDEFCDRDDS SDCCPDYRSF CIGEVDPIIS CEHNGVYFSK YNTTWDNCNE CRCLEGGSVQ 120
  121 CDEDLCLTDD AIVHSVNSIH RLGWSARKYD QWWGRKYSEG LKLRLGTKEP TYRVKAMTRL 180
  181 KNPTDGLPSS FNALDKWSSY ISEVPDQGWC GASWVLSTTS VASDRFAIQS KGKENVQLSA 240
  241 QNILSCTRRQ QGCEGGHLDA AWRYLHKKGV VDENCYPYTQ HRDTCKIRHN SRSLRANGCQ 300
  301 KPVNVDRDSL YTVGPAYSLN READIMAEIF HSGPVQATMR VNRDFFAYSG GVYRETAANR 360
  361 KAPTGFHSVK LVGWGEEHNG EKYWIAANSW GSWWGEHGYF RILRGSNECG IEEYVLASWP 420
  421 YVYSYYNVKS A

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
peptidase activity	4.90619850296986	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	4.64381885397949	bayes_pls_golite062009
endopeptidase activity	3.75054525912786	bayes_pls_golite062009
hydrolase activity	3.74079711298952	bayes_pls_golite062009
cysteine-type peptidase activity	2.71117522993364	bayes_pls_golite062009
cysteine-type endopeptidase activity	1.95802900199539	bayes_pls_golite062009
transporter activity	1.21845572420504	bayes_pls_golite062009
catalytic activity	1.05972260874031	bayes_pls_golite062009
binding	1.05436445615005	bayes_pls_golite062009
transmembrane transporter activity	1.00091316610003	bayes_pls_golite062009
protein binding	0.896934807256194	bayes_pls_golite062009
small conjugating protein-specific protease activity	0.649171767629235	bayes_pls_golite062009
thiolester hydrolase activity	0.59115205419466	bayes_pls_golite062009
substrate-specific transporter activity	0.484449686814032	bayes_pls_golite062009
kininogen binding	0.41283715939055	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.246369226539662	bayes_pls_golite062009
active transmembrane transporter activity	0.193338880082314	bayes_pls_golite062009
ubiquitin-specific protease activity	0.0101379718864654	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..88]	FFAS03	1.31	No description for 2ys0A was found.
2	View Details	[89..431]	PSI-BLAST	59.154902	Dipeptidyl peptidase I (cathepsin C), exclusion domain; Cathepsin C (dipeptidyl peptidase I), catalytic domain

Protein Overview: CG3074-PB, CG3074-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: