YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: Tbp-PA

General Information:
Name(s) found: Tbp-PA / FBpp0071596 [FlyBase]
Description(s) found:
Found 29 descriptions.
SHOW ALL
  • The gene TATA binding protein is referred to in FlyBase by the symbol Dmel\Tbp (CG9874, FBgn0003687). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17573705..17575145. It has the cytological map location 57F8. There is experimental evidence that it has the molecular function</span>: protein binding; transcription factor binding. There is experimental evidence that it is involved in the biological process</span>: snRNA transcription from RNA polymerase III promoter; regulation of transcription from RNA polymerase III promoter; tRNA transcription from RNA polymerase III promoter. 28 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 353 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    transcription factor TFIID complex [IPI][ISS][NAS]
    transcription factor TFIIIB complex [IPI]
    DNA-directed RNA polymerase III complex [IC]
    Biological Process: regulation of transcription, DNA-dependent [IEA]
    snRNA transcription from RNA polymerase III promoter [IDA]
    regulation of transcription from RNA polymerase III promoter [IMP]
    tRNA transcription from RNA polymerase III promoter [IDA][IMP]
    transcription initiation from RNA polymerase II promoter [ISS]
    regulation of transcription from RNA polymerase II promoter [NAS][TAS]
    Molecular Function: DNA binding [IEA][NAS]
    protein binding [IPI]
    general RNA polymerase II transcription factor activity [ISS]
    transcription factor binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQMLSPNFS IPSIGTPLHQ MEADQQIVAN PVYHPPAVSQ PDSLMPAPGS SSVQHQQQQQ  60
   61 QSDASGGSGL FGHEPSLPLA HKQMQSYQPS ASYQQQQQQQ QLQSQAPGGG GSTPQSMMQP 120
  121 QTPQSMMAHM MPMSERSVGG SGAGGGGDAL SNIHQTMGPS TPMTPATPGS ADPGIVPQLQ 180
  181 NIVSTVNLCC KLDLKKIALH ARNAEYNPKR FAAVIMRIRE PRTTALIFSS GKMVCTGAKS 240
  241 EDDSRLAARK YARIIQKLGF PAKFLDFKIQ NMVGSCDVKF PIRLEGLVLT HCNFSSYEPE 300
  301 LFPGLIYRMV RPRIVLLIFV SGKVVLTGAK VRQEIYDAFD KIFPILKKFK KQS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..145] PSI-BLAST 7.0 Sec24
    2 View Details [146..353] PSI-BLAST 87.09691 Structure of a Yeast TFIIA/TBP/TATA-box DNA Complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  10.1927670598446 bayes_pls_golite062009
  • RNA polymerase III transcription factor activity
    		•  8.4318102330583 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.66773099672992 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.97397050058114 bayes_pls_golite062009
  • DNA binding
    		•  3.93251147843671 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.82919607287537 bayes_pls_golite062009
  • RNA polymerase I transcription factor activity
    		•  3.24777019705869 bayes_pls_golite062009
  • binding
    		•  2.72886792846471 bayes_pls_golite062009
  • transcription factor activity
    		•  2.38288562794802 bayes_pls_golite062009
  • protein binding
    		•  1.96605926404517 bayes_pls_golite062009
  • transcription factor binding
    		•  1.86204668268867 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.59579825271822 bayes_pls_golite062009
  • transcription activator activity
    		•  1.5285505684695 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.16858275919592 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.312991469396539 bayes_pls_golite062009
  • chromatin binding
    		•  0.107733889697044 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle