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Protein Overview: edl-PA

General Information:
Name(s) found: edl-PA / FBpp0085834 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene ETS-domain lacking is referred to in FlyBase by the symbol Dmel\edl (CG15085, FBgn0023214). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14555026..14561037. It has the cytological map location 55E6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: photoreceptor cell development; regulation of Ras protein signal transduction; nuclear export; negative regulation of transcription; regulation of transcription, DNA-dependent; sensory organ development; embryonic pattern specification; regulation of epidermal growth factor receptor signaling pathway; regulation of phosphorylation. 22 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: external compound sense organ; peripheral nervous system; nervous system; compound cell cluster organ; imaginal precursor; embryonic nervous system; egg; primordium; adult segment; chorion; ommatidial precursor cluster; organ system; adult mesothoracic segment. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 177 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: nuclear export [IDA]
    embryonic pattern specification [IMP]
    negative regulation of transcription [IGI]
    photoreceptor cell development [IMP]
    regulation of Ras protein signal transduction [IPI]
    regulation of transcription, DNA-dependent [IPI]
    regulation of epidermal growth factor receptor signaling pathway [IEP][TAS]
    regulation of phosphorylation [IDA]
    sensory organ development [IMP]
    Molecular Function: protein binding [IPI]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVESSYTKY AGRVPPLDLT QVNGGQDLWG GNGGGNNASA RRHLHHPYQM LDKCRGGVTL  60
   61 ISASSAISST SNSSDDNNNR LMSADDGTTS LLHPLGSDGL PLDPRDWTRA DVWKWLINMA 120
  121 VSEGLEVTAE LPQKFPMNGK ALCLMSLDMY LCRVPVGGKM LYRDFRVRLA RAMALLS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..74] deduced N/A No confident structure predictions are available.
    2 View Details [75..177] PSI-BLAST 19.69897 Crystal Structure Of Yan-SAM/Mae-SAM Complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.98719702611774 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.74320052575423 bayes_pls_golite062009
  • protein binding
    		•  1.41065934507744 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.06494203590825 bayes_pls_golite062009
  • DNA binding
    		•  1.04271298640801 bayes_pls_golite062009
  • transcription factor activity
    		•  0.70384832940355 bayes_pls_golite062009
  • catalytic activity
    		•  0.415601732277814 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.273957228129152 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.131541277885705 bayes_pls_golite062009
  • transferase activity
    		•  0.129170106978418 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle