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Protein Overview: cato-PA

General Information:
Name(s) found: cato-PA / FBpp0086327 [FlyBase]
Description(s) found:
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  • gi|7302955|gb|AAF58026.1| cousin of atonal [Drosophila melanogaster] [NCBI NR]
  • gi|17137526|ref|NP_477344.1| cousin of atonal [Drosophila melanogaster] [NCBI NR]
  • gi|115646670|gb|ABI34244.2| RT01144p [Drosophila melanogaster] [NCBI NR]
  • gi|115646602|gb|ABI34217.2| RT01061p [Drosophila melanogaster] [NCBI NR]
  • The gene cousin of atonal is referred to in FlyBase by the symbol Dmel\cato (CG7760, FBgn0024249). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12165294..12165863. It has the cytological map location 53A4. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of transcription, DNA-dependent. 4 alleles are reported. The phenotypes of these alleles are annotated with: scolopidium; macrochaeta; chordotonal organ. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG7760-PA translation from_gene[CG7760 cato FBgn0024249] seq_release:3 mol_weight=20561 cds_boundaries:(2R:11,341,517..11,342,083[-]) aa_length:189 transcript_info:[CG7760-RA seq_release:3] gene_info:[gene symbol:cato FBgn0024249 gene_boundaries:(2R:1 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V7M2) CATO protein [DrosMelano7227.FASTAC.txt]
  • (AE003807) cato gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG7760-PA [Drosophila melanogaster]gi|17137526|ref|NP_477344.1| CG7760-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(12165294..12165863); ID=FBpp0086327; name=cato-PA; parent=FBgn0024249,FBtr0087183; dbxref=GB_protein:AAF58026.1,FlyBase:FBpp0086327,FlyBase_Annotation_IDs:CG7760-PA,REFSEQ:NP_477344,GB_protein:AAF58026; MD5=74267b888e484bfb [fly-100309-contam.fasta]
  • RT01144p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • cousin of atonal CG7760-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RT01061p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG7760-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(12165294..12165863); ID=FBpp0086327; name=cato-PA; parent=FBgn0024249,FBtr0087183; dbxref=GB_protein:AAF58026.1,FlyBase:FBpp0086327,FlyBase_Annotation_IDs:CG7760-PA,REFSEQ:NP_477344,GB_protein:AAF58026; MD5=74267b888e484bfbabee2228f611b59e; length=189; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(12165294..12165863); ID=FBpp0086327; name=cato-PA; parent=FBgn0024249,FBtr0087183; dbxref=GB_protein:AAF58026.1,FlyBase:FBpp0086327,FlyBase_Annotation_IDs:CG7760-PA,REFSEQ:NP_477344,GB_protein:AAF58026; MD5=74267b888e484bfbabee2228f611b59e; length=189; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Cousin of atonal OS=Drosophila melanogaster GN=cato PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(12165294..12165863); ID=FBpp0086327; name=cato-PA; parent=FBgn0024249,FBtr0087183; dbxref=GB_protein:AAF58026.1,FlyBase:FBpp0086327,FlyBase_Annotation_IDs:CG7760-PA,REFSEQ:NP_477344,GB_protein:AAF58026,FlyMine:FBpp0086327,modMine:FBpp0086327; MD5=74267b888e484bfbabee2228f611b59e; length=189; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • Cousin of atonal OS=Drosophila melanogaster GN=cato PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=2R:complement(16277789..16278358); ID=FBpp0086327; name=cato-PA; parent=FBgn0024249,FBtr0087183; dbxref=GB_protein:AAF58026.1,FlyBase:FBpp0086327,FlyBase_Annotation_IDs:CG7760-PA,REFSEQ:NP_477344,GB_protein:AAF58026,FlyMine:FBpp0086327,modMine:FBpp0086327; MD5=74267b888e484bfbabee2228f611b59e; length=189; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(16277789..16278358); ID=FBpp0086327; name=cato-PA; parent=FBgn0024249,FBtr0087183; dbxref=GB_protein:AAF58026.1,FlyBase:FBpp0086327,FlyBase_Annotation_IDs:CG7760-PA,REFSEQ:NP_477344,GB_protein:AAF58026,FlyMine:FBpp0086327,modMine:FBpp0086327; MD5=74267b888e484bfbabee2228f611b59e; length=189; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0086327 type=protein; loc=2R:complement(16277789..16278358); ID=FBpp0086327; name=cato-PA; parent=FBgn0024249,FBtr0087183; dbxref=GB_protein:AAF58026.1,FlyBase:FBpp0086327,FlyBase_Annotation_IDs:CG7760-PA,REFSEQ:NP_477344,GB_protein:AAF58026,FlyMine:FBpp0086327,modMine:FBpp0086327; MD5=74267b888e484bfbabee2228f611b59e; length=189; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(16277789..16278358); ID=FBpp0086327; name=cato-PA; parent=FBgn0024249,FBtr0087183; dbxref=GB_protein:AAF58026.1,FlyBase:FBpp0086327,FlyBase_Annotation_IDs:CG7760-PA,REFSEQ:NP_477344,GB_protein:AAF58026,UniProt/TrEMBL:Q0IGT4,FlyMine:FBpp0086327,modMine:FBpp0086327; MD5=74267b888e484bfbabee2228f611b59e; length=189; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 189 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: regulation of transcription, DNA-dependent [ISS]
    regulation of transcription [IEA]
    sensory organ development [TAS]
    Molecular Function: transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYYYSSASE EDGSSQYLGS PNYNLTQLPP VSGQDYGQGA FLSPEWQFLD AAGGTQTELG  60
   61 PIMEAQGQHT QPQTKRRSNS FTGSDGRKSS PEQTNLSPTV QKRRRQAANA RERKRMNGLN 120
  121 AAFERLREVV PAPSIDQKLS KFETLQMAQS YILALCDLLN NGDVEVDAAA YTIFGDSDSG 180
  181 FGLSGGSLS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..95] deduced N/A No confident structure predictions are available.
    2 View Details [96..189] PSI-BLAST 13.0 Solution Structure of Max B-HLH-LZ

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.38658950816179 bayes_pls_golite062009
  • DNA binding
    		•  5.18654839258297 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.05768805749761 bayes_pls_golite062009
  • transcription factor activity
    		•  4.78039531631248 bayes_pls_golite062009
  • binding
    		•  3.81829206350975 bayes_pls_golite062009
  • transcription factor binding
    		•  2.61163564741984 bayes_pls_golite062009
  • transcription activator activity
    		•  2.5495467409976 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.48787404513864 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.31910036997977 bayes_pls_golite062009
  • protein binding
    		•  1.59929864805879 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.52770895937238 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  1.46304579811572 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.955588849035129 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.801830750183111 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.3513586903977 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle