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View Structure Prediction Details

Protein: cato-PA
Organism: Drosophila melanogaster
Length: 189 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cato-PA.

Description E-value Query
Range
Subject
Range
gi|4877830 - gi|4877830|gb|AAD31451.1|AF134869_1 CATO [Drosophila melanogaster]
133.0 [0..1] [189..1]
gi|214590, gi|104139 - gi|214590|gb|AAA49901.1| MyoD1 homologous protein; putative, pir||B34783 myogenesis protein MyoDa, s...
127.0 [0..21] [188..13]
gi|54695320 - gi|54695320|emb|CAH65602.1| MyoD protein [Salmo salar]
118.0 [0..23] [187..4]
gi|12744734 - gi|12744734|gb|AAK06755.1|AF318503_1 Myod [Danio rerio]
117.0 [0..30] [187..11]
gi|45510881 - gi|45510881|gb|AAS67038.1| MyoD [Ictalurus furcatus]
117.0 [0..30] [187..11]
gi|2801465, gi|9... - gi|9629901|ref|NP_045935.1| p110 [Avian myelocytomatosis virus], gi|61609|emb|CAA24499.1| p96 polypr...
gi|625263 - gi|625263|pir||FOFV29 gag-myc polyprotein - avian myelocytomatosis virus MC29 (provirus)
117.0 [0..36] [172..723]
gi|45510883 - gi|45510883|gb|AAS67039.1| MyoD [Ameiurus catus]
116.0 [0..23] [187..4]
gi|37675391 - gi|37675391|gb|AAQ97204.1| MyoD [Sternopygus macrurus]
116.0 [0..31] [187..12]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYYYSSASE EDGSSQYLGS PNYNLTQLPP VSGQDYGQGA FLSPEWQFLD AAGGTQTELG  60
   61 PIMEAQGQHT QPQTKRRSNS FTGSDGRKSS PEQTN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [96-189]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSPTVQKRRR QAANARERKR MNGLNAAFER LREVVPAPSI DQKLSKFETL QMAQSYILAL  60
   61 CDLLNNGDVE VDAAAYTIFG DSDSGFGLSG GSLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1r05A
Description: Solution Structure of Max B-HLH-LZ
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
transcription activator activity 2.5495467409976 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.48787404513864 bayes_pls_golite062009
sequence-specific DNA binding 2.31910036997977 bayes_pls_golite062009
protein binding 1.59929864805879 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 1.46304579811572 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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