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Protein Overview: casp-PB, casp-PA

General Information:
Name(s) found: casp-PB / FBpp0086398 [FlyBase]
casp-PA / FBpp0086397 [FlyBase]
Description(s) found:
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  • gi|7303003|gb|AAF58073.1| caspar, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|45552647|ref|NP_995848.1| caspar, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|45445531|gb|AAS64841.1| caspar, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|21483370|gb|AAM52660.1| LD03368p [Drosophila melanogaster] [NCBI NR]
  • gi|20130031|ref|NP_611080.1| caspar, isoform A [Drosophila melanogaster] [NCBI NR]
  • The gene caspar is referred to in FlyBase by the symbol Dmel\casp (CG8400, FBgn0034068). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11912133..11915666. It has the cytological map location 52D14-52D15. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: defense response to Gram-negative bacterium. 5 alleles are reported. The phenotype of these alleles is annotated with: fat body. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG8400-PA translation from_gene[CG8400 CG8400 FBgn0034068] seq_release:3 mol_weight=78441 cds_boundaries:(2R:11,088,704..11,091,647[-]) aa_length:695 transcript_info:[CG8400-RA seq_release:3] gene_info:[gene symbol:CG8400 FBgn0034068 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V7I2) CG8400 protein (LD03368p) [DrosMelano7227.FASTAC.txt]
  • (AE003808) CG8400 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8400-PB, isoform B [Drosophila melanogaster]gi|7303003|gb|AAF58073.1| CG8400-PA, isoform A [Drosophila melanogaster]gi|21483370|gb|AAM52660.1| LD03368p [Drosophila melanogaster]gi|20130031|ref|NP_611080.1| CG8400-PA [Drosophila melanogaster]gi|45552 [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(11912481..11912639,11912696..11912815,11912878..11913152,11913214..11913359,11913418..11913572,11913640..11913785,11913844..11914051,11914116..11914317,11914372..11914561,11914640..11914783,11914842..11915076,11915170..1191 [fly-100309-contam.fasta]
  • CG8400-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG8400-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LD03368p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(11912481..11912639,11912696..11912815,11912878..11913152,11913214..11913359,11913418..11913572,11913640..11913785,11913844..11914051,11914116..11914317,11914372..11914561,11914640..11914783,11914842..11915076,11915170..11915238,11915389..11915427); ID=FBpp0086397; name=casp-PA; parent=FBgn0034068,FBtr0087259; dbxref=FlyBase:FBpp0086397,FlyBase_Annotation_IDs:CG8400-PA,GB_protein:AAF58073.1,REFSEQ:NP_611080,GB_protein:AAF58073; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(11912481..11912639,11912696..11912815,11912878..11913152,11913214..11913359,11913418..11913572,11913640..11913785,11913844..11914051,11914116..11914317,11914372..11914561,11914640..11914783,11914842..11915076,11915170..11915238,11915389..11915427); ID=FBpp0086398; name=casp-PB; parent=FBgn0034068,FBtr0087260; dbxref=FlyBase:FBpp0086398,FlyBase_Annotation_IDs:CG8400-PB,GB_protein:AAS64841.1,REFSEQ:NP_995848,GB_protein:AAS64841; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(11912481..11912639,11912696..11912815,11912878..11913152,11913214..11913359,11913418..11913572,11913640..11913785,11913844..11914051,11914116..11914317,11914372..11914561,11914640..11914783,11914842..11915076,11915170..11915238,11915389..11915427); ID=FBpp0086397; name=casp-PA; parent=FBgn0034068,FBtr0087259; dbxref=FlyBase:FBpp0086397,FlyBase_Annotation_IDs:CG8400-PA,GB_protein:AAF58073.1,REFSEQ:NP_611080,GB_protein:AAF58073; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2R:complement(11912481..11912639,11912696..11912815,11912878..11913152,11913214..11913359,11913418..11913572,11913640..11913785,11913844..11914051,11914116..11914317,11914372..11914561,11914640..11914783,11914842..11915076,11915170..11915238,11915389..11915427); ID=FBpp0086398; name=casp-PB; parent=FBgn0034068,FBtr0087260; dbxref=FlyBase:FBpp0086398,FlyBase_Annotation_IDs:CG8400-PB,GB_protein:AAS64841.1,REFSEQ:NP_995848,GB_protein:AAS64841; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Caspar, isoform A OS=Drosophila melanogaster GN=casp PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(11912481..11912639,11912696..11912815,11912878..11913152,11913214..11913359,11913418..11913572,11913640..11913785,11913844..11914051,11914116..11914317,11914372..11914561,11914640..11914783,11914842..11915076,11915170..11915238,11915389..11915427); ID=FBpp0086397; name=casp-PA; parent=FBgn0034068,FBtr0087259; dbxref=FlyBase:FBpp0086397,FlyBase_Annotation_IDs:CG8400-PA,GB_protein:AAF58073.1,REFSEQ:NP_611080,GB_protein:AAF58073; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(11912481..11912639,11912696..11912815,11912878..11913152,11913214..11913359,11913418..11913572,11913640..11913785,11913844..11914051,11914116..11914317,11914372..11914561,11914640..11914783,11914842..11915076,11915170..11915238,11915389..11915427); ID=FBpp0086398; name=casp-PB; parent=FBgn0034068,FBtr0087260; dbxref=FlyBase:FBpp0086398,FlyBase_Annotation_IDs:CG8400-PB,GB_protein:AAS64841.1,REFSEQ:NP_995848,GB_protein:AAS64841,FlyMine:FBpp0086398,modMine:FBpp0086398; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • Caspar, isoform A OS=Drosophila melanogaster GN=casp PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=2R:complement(join(16027884..16027922,16027665..16027733,16027337..16027571,16027135..16027278,16026867..16027056,16026611..16026812,16026339..16026546,16026135..16026280,16025913..16026067,16025709..16025854,16025373..16025647,16025191..16025310,16024976..16025134)); ID=FBpp0086397; name=casp-PA; parent=FBgn0034068,FBtr0087259; dbxref=FlyBase:FBpp0086397,FlyBase_Annotation_IDs:CG8400-PA,GB_protein:AAF58073.1,REFSEQ:NP_611080,GB_protein:AAF58073; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(16027884..16027922,16027665..16027733,16027337..16027571,16027135..16027278,16026867..16027056,16026611..16026812,16026339..16026546,16026135..16026280,16025913..16026067,16025709..16025854,16025373..16025647,16025191..16025310,16024976..16025134)); ID=FBpp0086398; name=casp-PB; parent=FBgn0034068,FBtr0087260; dbxref=FlyBase:FBpp0086398,FlyBase_Annotation_IDs:CG8400-PB,GB_protein:AAS64841.1,REFSEQ:NP_995848,GB_protein:AAS64841,FlyMine:FBpp0086398,modMine:FBpp0086398; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(16027884..16027922,16027665..16027733,16027337..16027571,16027135..16027278,16026867..16027056,16026611..16026812,16026339..16026546,16026135..16026280,16025913..16026067,16025709..16025854,16025373..16025647,16025191..16025310,16024976..16025134)); ID=FBpp0086397; name=casp-PA; parent=FBgn0034068,FBtr0087259; dbxref=FlyBase:FBpp0086397,FlyBase_Annotation_IDs:CG8400-PA,GB_protein:AAF58073.1,REFSEQ:NP_611080,GB_protein:AAF58073; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2R:complement(join(16027884..16027922,16027665..16027733,16027337..16027571,16027135..16027278,16026867..16027056,16026611..16026812,16026339..16026546,16026135..16026280,16025913..16026067,16025709..16025854,16025373..16025647,16025191..16025310,16024976..16025134)); ID=FBpp0086398; name=casp-PB; parent=FBgn0034068,FBtr0087260; dbxref=FlyBase:FBpp0086398,FlyBase_Annotation_IDs:CG8400-PB,GB_protein:AAS64841.1,REFSEQ:NP_995848,GB_protein:AAS64841,FlyMine:FBpp0086398,modMine:FBpp0086398; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0086397 type=protein; loc=2R:complement(join(16027884..16027922,16027665..16027733,16027337..16027571,16027135..16027278,16026867..16027056,16026611..16026812,16026339..16026546,16026135..16026280,16025913..16026067,16025709..16025854,16025373..16025647,16025191..16025310,16024976..16025134)); ID=FBpp0086397; name=casp-PA; parent=FBgn0034068,FBtr0087259; dbxref=FlyBase:FBpp0086397,FlyBase_Annotation_IDs:CG8400-PA,GB_protein:AAF58073.1,REFSEQ:NP_611080,GB_protein:AAF58073; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0086398 type=protein; loc=2R:complement(join(16027884..16027922,16027665..16027733,16027337..16027571,16027135..16027278,16026867..16027056,16026611..16026812,16026339..16026546,16026135..16026280,16025913..16026067,16025709..16025854,16025373..16025647,16025191..16025310,16024976..16025134)); ID=FBpp0086398; name=casp-PB; parent=FBgn0034068,FBtr0087260; dbxref=FlyBase:FBpp0086398,FlyBase_Annotation_IDs:CG8400-PB,GB_protein:AAS64841.1,REFSEQ:NP_995848,GB_protein:AAS64841,FlyMine:FBpp0086398,modMine:FBpp0086398; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(16027884..16027922,16027665..16027733,16027337..16027571,16027135..16027278,16026867..16027056,16026611..16026812,16026339..16026546,16026135..16026280,16025913..16026067,16025709..16025854,16025373..16025647,16025191..16025310,16024976..16025134)); ID=FBpp0086397; name=casp-PA; parent=FBgn0034068,FBtr0087259; dbxref=FlyBase:FBpp0086397,FlyBase_Annotation_IDs:CG8400-PA,GB_protein:AAF58073.1,REFSEQ:NP_611080,GB_protein:AAF58073,UniProt/TrEMBL:Q7JUP3; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2R:complement(join(16027884..16027922,16027665..16027733,16027337..16027571,16027135..16027278,16026867..16027056,16026611..16026812,16026339..16026546,16026135..16026280,16025913..16026067,16025709..16025854,16025373..16025647,16025191..16025310,16024976..16025134)); ID=FBpp0086398; name=casp-PB; parent=FBgn0034068,FBtr0087260; dbxref=FlyBase:FBpp0086398,FlyBase_Annotation_IDs:CG8400-PB,GB_protein:AAS64841.1,REFSEQ:NP_995848,GB_protein:AAS64841,UniProt/TrEMBL:Q7JUP3,FlyMine:FBpp0086398,modMine:FBpp0086398; MD5=89e0192ccc9ea382ff48acd4a16ba9c7; length=695; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 695 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: defense response to Gram-negative bacterium [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSENKDEALT SFQSITGIDD VGEAFSHLEA ADWNLVEALS RVIPHEDAPL TSPHPILVPE  60
   61 PPARNAVEST NGFRPPGFDE MPGTSNASGF FAAALQNQNQ NLNLNQPHIQ QRFPTSQLLA 120
  121 QLTSSINLDP ASSQNNNQNV ITFNIHFNQQ LYQLRLPSEA TVEQLKRKIF AETSVPVCRQ 180
  181 AIRGWPPSKA SDAQQLGTRL CNLDLSPENE LILVDLTEDG FMDTEQDEVT QRVDKDFTIF 240
  241 IQFESDPPLT LSLPGRMTVQ EVKMNVFDIK SIPVRHQEWT GWPNGCDNDT TLAQSGIGLS 300
  301 HRFAVRSTER SAPTNSNQHN AFDVVTVDSE SSTDEFEDAT DFNNAEYIFT DSPPAQPPNR 360
  361 HLIPNDTDDE ISGSTQFVEN YKARYGEPCP EFFVGSLENA KQLACLRSAK ERKLLAIYLH 420
  421 HGKSILSNVF CDQLMKHESI IQTFKEKFVL YGWDMTYESN KDMFLSSLTA CISSNASLTA 480
  481 RNIKLDKLPA IMLVGKSRQL GSNCEVLSVI HGNIGLDDLL TRLIETCEMF EEQLQVEIRQ 540
  541 EDERAARDQV KAEQDMAYQE TLQADMAKDA AKRQKEAAQL AERKRMESER AEEDARRESI 600
  601 RLVAQQSLPQ EPSEQETGTS KIRVRKPTGD FLERRFFINN NLQDLLNFVT ANGFLIEEYK 660
  661 LISSWPRRDL TAIESSQTLE SLKLYPQETV ILEER

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..75] FFAS03 1.55 No description for 2damA was found.
    2 View Details [76..148] deduced N/A No confident structure predictions are available.
    3 View Details [149..328] PSI-BLAST 19.154902 Crystal Structure of ISG15, the Interferon-Induced Ubiquitin Cross Reactive Protein
    4 View Details [329..511] PSI-BLAST 23.522879 No description for 2dlxA was found.
    5 View Details [512..615] PSI-BLAST 6.39794 No description for 2i1jA was found.
    6 View Details [616..695] PSI-BLAST 21.69897 Fas-assosiated factor 1, Faf1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • protein binding
    		•  2.9188688008729 bayes_pls_golite062009
  • binding
    		•  2.786655943372 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  2.06714283858345 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.48147454986498 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.42747465816672 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.32707653701567 bayes_pls_golite062009
  • DNA binding
    		•  1.22622447288034 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  1.0818414663245 bayes_pls_golite062009
  • signal transducer activity
    		•  1.05682194741929 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.05682194741929 bayes_pls_golite062009
  • hydrolase activity
    		•  0.614233748923048 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.334601927012824 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.315664702789604 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.209042683238025 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.162163146322721 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  0.119687312084129 bayes_pls_golite062009
  • receptor binding
    		•  0.020939932812017 bayes_pls_golite062009
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  1.51590630336241 bayes_pls_golite062009
  • antioxidant activity
    		•  1.41754012367769 bayes_pls_golite062009
  • binding
    		•  1.25802922431343 bayes_pls_golite062009
  • peroxidase activity
    		•  1.22546563390242 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  1.22546563390242 bayes_pls_golite062009
  • protein binding
    		•  1.18479617596618 bayes_pls_golite062009
  • signal transducer activity
    		•  1.03696928411308 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.03696928411308 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • hydrolase activity
    		•  0.517269321619613 bayes_pls_golite062009
  • glutathione peroxidase activity
    		•  0.29729802281773 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  0.13913802190798 bayes_pls_golite062009
  • peroxiredoxin activity
    		•  0.0343881005856616 bayes_pls_golite062009
    5 No functions predicted.
    6
    Term Confidence Notes
  • protein binding
    		•  2.9188688008729 bayes_pls_golite062009
  • binding
    		•  2.786655943372 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  2.06714283858345 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.48147454986498 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.42747465816672 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.32707653701567 bayes_pls_golite062009
  • DNA binding
    		•  1.22622447288034 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  1.0818414663245 bayes_pls_golite062009
  • signal transducer activity
    		•  1.05682194741929 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.05682194741929 bayes_pls_golite062009
  • hydrolase activity
    		•  0.614233748923048 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.334601927012824 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.315664702789604 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.209042683238025 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.162163146322721 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  0.119687312084129 bayes_pls_golite062009
  • receptor binding
    		•  0.020939932812017 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle