YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: scb-PB

General Information:
Name(s) found: scb-PB / FBpp0086501 [FlyBase]
Description(s) found:
Found 25 descriptions.
SHOW ALL
  • The gene scab is referred to in FlyBase by the symbol Dmel\scb (CG8095, FBgn0003328). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11136290..11146003. It has the cytological map location 51E10-51E11. There is experimental evidence that it has the molecular function</span>: cell adhesion molecule binding; receptor activity. There is experimental evidence that it is involved in the biological process</span>: dorsal closure; axon guidance; cell adhesion; phagocytosis, engulfment. 31 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; anatomical structure; multi-cell-component structure; extended germ band embryo; nervous system; portion of tissue; integumentary system; cell leading edge; adult trachea; protein complex; neuromuscular junction; embryonic trachea; late extended germ band embryo. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1115 amino acids

    Gene Ontology:
    Cellular Component: focal adhesion [ISS]
    integral to membrane [NAS]
    integrin complex [IEA][ISS][NAS]
    plasma membrane [ISS]
    Biological Process: dorsal closure [IMP][NAS][TAS]
    cell-matrix adhesion [TAS]
    calcium-dependent cell-cell adhesion [ISS]
    midgut development [TAS]
    locomotion [NAS]
    heterophilic cell-cell adhesion [TAS]
    axon guidance [IMP]
    cell adhesion [IPI][ISS][NAS][TAS]
    olfactory learning [NAS]
    salivary gland development [NAS]
    memory [NAS][TAS]
    open tracheal system development [NAS]
    learning or memory [NAS]
    heart development [NAS]
    short-term memory [TAS]
    phagocytosis, engulfment [IMP]
    calcium-dependent cell-matrix adhesion [ISS]
    cell migration [TAS]
    Molecular Function: cell adhesion molecule binding [IPI][ISS][NAS][TAS]
    laminin receptor activity [NAS]
    structural molecule activity [NAS]
    receptor activity [IPI][ISS][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNAESTMFPH IFLALLALIS HIEAFNFMPR PSRVINSPKH LKFHINQTRS SYFGYTLVIR  60
   61 QTSIIVGAPR AQSTLESQRT INETGAIYRC SLTNGVCSPY VLDSRGNVDA PYSEYTFDSE 120
  121 RKDFQWLGGS MDGGTKDTDK LLVCAPRFYA PSSRDNHLHG VCYWVNNTVA STPQHVTRIS 180
  181 PLRLKSEQVK EEDNGNKASF FYIMGELGLS AHVADDNTKF LIGAPGINTW RGSVILYRQV 240
  241 DPVDNPTASR RDTSKALRRT YRDVDSNDYT PEHYAPEIPT PGLWGQEEDS YFGYAVSSGF 300
  301 FDSSNPTKLL YVATAPQANK QSGEAYIFDV RGKSIHKYHV FRGEQFGEYF GYSVLAEDLN 360
  361 GDGKTDVIVS APQHALEDSH DNGAIYVFIN KGFFNFERQI LRSPVETMAR FGTALSRLGD 420
  421 INHDGYNDVA VGAPFAGNGT VFIYLGSENG LRDQPSQRLD APSQQPSKYG SHMFGHGLSR 480
  481 GSDIDGNGFN DFAIGAPNAE AVYLYRAYPV VKVHATVKSE SREIKPEQEK VKITACYRLS 540
  541 TTSTDKLVQE QELAIRIAMD KQLKRVKFTQ TQTNEISFKV NANFGEQCRD FETQVRYSEK 600
  601 DIFTPIDLEM HYELTKKVPD SEEFCETCAI VDPTEPKVST QNIIFSTGCA TDVCTADLQL 660
  661 RSKDVSPTYI LGSADTLRLN YEITNIGETA YLPQFNVTST SRLAFAQVPG NCKVVDAVMV 720
  721 CDLNRGRPLA KGDTDSVTIS FDVSQLSGQS LIIHAEVFST GYEQNPTDNR QTNVIGLKEF 780
  781 TEIDASGGQT NSQIDLEHYS NSAEIVNNYE IKSNGPSVIE QLTVSFYIPI AYKVAGSTAI 840
  841 IPIINVTSLK MQASYDSQLL SIDLYDQNNT MLVVDPVEVT TTLSGGLERT VITQNRQSYD 900
  901 IHTSGHVHQT MEVLDTSMVA TASMSRKRRD LKALTANREQ YARISNVKAH DLLSDDFKGK 960
  961 LPVNRTIVFN CRDPEMTICV RAEMRVHFRP EKSINLNMRY SVDLNEVNAI LVDPWEYFVI1020
 1021 LTDLKLQKKG DPTSTSFSIN RRIEPNIISK HQETGLPIWI IIVSVIGGLL LLSAISYLLY1080
 1081 KFGFFNRTKK DELDRLVQQN PVEPEAENLN SGGNN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1115] PSI-BLAST 173.0 Thigh, calf-1 and calf-2 domains of integrin alpha; Integrin alpha N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cell adhesion molecule binding
    		•  4.38909417354069 bayes_pls_golite062009
  • receptor activity
    		•  3.07436728891089 bayes_pls_golite062009
  • protein binding
    		•  2.93314130654223 bayes_pls_golite062009
  • binding
    		•  2.38505574840555 bayes_pls_golite062009
  • signal transducer activity
    		•  2.30570215634503 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.30570215634503 bayes_pls_golite062009
  • extracellular matrix binding
    		•  2.29992000538847 bayes_pls_golite062009
  • fibronectin binding
    		•  2.1460818503023 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.89652634417708 bayes_pls_golite062009
  • integrin binding
    		•  1.46467851042106 bayes_pls_golite062009
  • laminin receptor activity
    		•  0.57752974249266 bayes_pls_golite062009
  • protein complex binding
    		•  0.317709418149211 bayes_pls_golite062009
  • receptor binding
    		•  0.272415627526009 bayes_pls_golite062009
  • laminin binding
    		•  0.0766626920324303 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle