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Protein Overview: tra2-PG, tra2-PA...

General Information:
Name(s) found: tra2-PF / FBpp0088947 [FlyBase]
tra2-PG / FBpp0088946 [FlyBase]
tra2-PA / FBpp0088562 [FlyBase]
Description(s) found:
Found 53 descriptions.
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  • The gene transformer 2 is referred to in FlyBase by the symbol Dmel\tra2 (CG10128, FBgn0003742). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10489509..10491857. It has the cytological map location 51B6. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: female sex determination; mRNA processing; regulation of nuclear mRNA splicing, via spliceosome; reproduction; regulation of alternative nuclear mRNA splicing, via spliceosome. 68 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; adult segment; larval abdominal segment 8; adult; larval abdominal segment; spermatozoon; primordium; female genitalia; germline cell; abdominal segment 7; metatarsus; imaginal precursor. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
  • The gene transformer 2 is referred to in FlyBase by the symbol Dmel\tra2 (CG10128, FBgn0003742). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10489509..10491857. It has the cytological map location 51B6. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: female sex determination; mRNA processing; regulation of nuclear mRNA splicing, via spliceosome; reproduction; regulation of alternative nuclear mRNA splicing, via spliceosome. 68 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; adult segment; larval abdominal segment 8; adult; larval abdominal segment; spermatozoon; primordium; female genitalia; germline cell; abdominal segment 7; metatarsus; imaginal precursor. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
  • The gene transformer 2 is referred to in FlyBase by the symbol Dmel\tra2 (CG10128, FBgn0003742). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10489509..10491857. It has the cytological map location 51B6. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: female sex determination; mRNA processing; regulation of nuclear mRNA splicing, via spliceosome; reproduction; regulation of alternative nuclear mRNA splicing, via spliceosome. 68 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; adult segment; larval abdominal segment 8; adult; larval abdominal segment; spermatozoon; primordium; female genitalia; germline cell; abdominal segment 7; metatarsus; imaginal precursor. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 264 amino acids

    Gene Ontology:
    Cellular Component: precatalytic spliceosome [IDA]
    Biological Process: RNA splicing [NAS]
    regulation of alternative nuclear mRNA splicing, via spliceosome [IMP]
    spermatogenesis [NAS]
    regulation of nuclear mRNA splicing, via spliceosome [IDA]
    male somatic sex determination [TAS]
    female somatic sex determination [NAS][TAS]
    sex determination [NAS]
    mRNA processing [IMP][NAS]
    female sex determination [IMP]
    reproduction [IMP][NAS]
    spliceosome assembly [NAS]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: nucleic acid binding [IEA]
    nucleotide binding [IEA]
    mRNA binding [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDREPLSSGR LHCSARYKHK RSASSSSAGT TSSGHKDRRS DYDYCGSRRH QRSSSRRRSR  60
   61 SRSSSESPPP EPRHRSGRSS RDRERMHKSR EHPQASRCIG VFGLNTNTSQ HKVRELFNKY 120
  121 GPIERIQMVI DAQTQRSRGF CFIYFEKLSD ARAAKDSCSG IEVDGRRIRV DFSITQRAHT 180
  181 PTPGVYLGRQ PRGKAPRSFS PRRGRRVYHD RSASPYDNYR DRYDYRNDRY DRNLRRSPSR 240
  241 NRYTRNRSYS RSRSPQLRRT SSRY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..264] PSI-BLAST 42.69897 Nuclear ribonucleoprotein A1 (RNP A1, UP1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  3.75748736237159 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.30499161454806 bayes_pls_golite062009
  • mRNA binding
    		•  2.67679675039933 bayes_pls_golite062009
  • binding
    		•  2.30438455421982 bayes_pls_golite062009
    		• 0.84389121154917 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.61170301639809 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.40943492051131 bayes_pls_golite062009
  • protein binding
    		•  0.403675976995418 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.361110886317161 bayes_pls_golite062009
  • DNA binding
    		•  0.139895000724487 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle