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Protein Overview: FBpp0308986, CG8...

General Information:
Name(s) found: FBpp0308986 [FlyBase]
CG8257-PA / FBpp0086706 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • type=protein; loc=2R:complement(10046931..10048596,10048656..10048666); ID=FBpp0308986; name=CG8257-PB; parent=FBgn0033900,FBtr0339965; dbxref=FlyBase:FBpp0308986,FlyBase_Annotation_IDs:CG8257-PB; MD5=e264535eb8bbfda3ea605f63a5963857; length=558; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8257 (CG8257, FBgn0033900). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10046893..10048732. It has the cytological map location 50E1. Based on sequence similarity, it is predicted to have molecular function</span>: cysteine-tRNA ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cysteinyl-tRNA aminoacylation. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 558 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: cysteinyl-tRNA aminoacylation [IEA]
    Molecular Function: ATP binding [IEA]
    cysteine-tRNA ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSLKEGLRA LNSRTRPALI CRRNISEEAP KQDSPFKWRK PIGQHTGINI YNHGLRQKVP  60
   61 LILRNPQMVT WYTCGPTVYD SAHLGHASTY VKVDILQRIL RDYFKINLVT AMNITDVDDK 120
  121 IIKRAQLAGL DWQKMARAYE AEFRQDMLRL NVQAPDVRSH VTTTMPVIIQ FIQQLIDGKQ 180
  181 AYVTPDNSVY FDVSKSKNYG KLQNLGLSED KLDPIKRNTA DFALWKARKS GSEPTWAAPW 240
  241 GGEGRPGWHI ECSAIAGLFF GRQLDIHAGG LDLRFPHHEN EEAQCCARYK TDQWVNYWVH 300
  301 TGQLHMVGDR EKMSKSLGNT ISVSELLKKY TADEFRMACL LSNYRNAMPY SDQLMVTARQ 360
  361 TLQRFRNFQA DLSAYTQFLK PVHLLDEGAL KAQLTHTVTE FDNCLRDDFD TARAISVLID 420
  421 QMSSISRCIN EQQVDAQEEP AYCIDLLLAA GNFINRAIVT FGLSELQDKE SLQEKVSFTD 480
  481 HSIDPNLLVN DVINVRGRMR ERATSGNVKN PQLLAACDEL RSLLQQHGIQ VRDHKQGSSW 540
  541 VFAVSCEKQD DKSKSSAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..558] PSI-BLAST 103.0 Cysteinyl-tRNA synthetase (CysRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  5.23703961447809 bayes_pls_golite062009
  • isoleucine-tRNA ligase activity
    		•  3.76808520367507 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.01261843164558 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.13743634264647 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.2293846471193 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.161799496958314 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.126511747475258 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle