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Protein Overview: pea-PA

General Information:
Name(s) found: pea-PA / FBpp0086647 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene peanuts is referred to in FlyBase by the symbol Dmel\pea (CG8241, FBgn0086895). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10040661..10044611. It has the cytological map location 50E1. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent RNA helicase activity. There is experimental evidence that it is involved in the biological process</span>: spermatid development; regulation of alternative nuclear mRNA splicing, via spliceosome. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1242 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC]
    catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    spliceosomal complex [ISS]
    Biological Process: spermatid development [IMP]
    regulation of alternative nuclear mRNA splicing, via spliceosome [IMP]
    nuclear mRNA splicing, via spliceosome [IC][ISS]
    Molecular Function: ATP binding [IEA]
    RNA binding [IEA]
    ATP-dependent RNA helicase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDELQKLEYL SLVSKICTEL DNHLGINDKD LAEFIIDLEN KNRTYDTFRK ALLDNGAEFP  60
   61 DSLVQNLQRI INLMRPSRPG GASQEKTVGD KKEDKKSQLL KMFPGLALPN DTYSKKEESD 120
  121 DDEKVKAKPE KHSETHKKTD MSDVDAAMME LEALAPGEGA TLVRPHKEVS SRDRHKRRSR 180
  181 DRDTKRRSRS REDRHSDRRR SRSRDKERRR RSRSRDNRRR SRSREDRDRD RDRRHKSSSS 240
  241 RDHHERRRRS RSRSTERRDR RDRSRDCSEK MPPPSAAMTD DPEAGKIYSG KIANIVPFGC 300
  301 FVQLFGLRKR WEGLVHISQL RAEGRVTDVT EVVTRNQTVK VKVMSITGQK VSLSMKEVDQ 360
  361 DSGKDLNPLS HAPEDDESLR DRNPDGPFSS STSMLNLQGN GMEGDEHESR KRVTRISSPE 420
  421 RWEIKQMISS GVLDRSEMPD FDEETGLLPK DEDDEADIEI EIVEEEPPFL SGHGRALHDL 480
  481 SPVRIVKNPD GSLAQAAMMQ SALSKERREQ KMLQREQEIE AMPTSLNKNW IDPLPEDESR 540
  541 SLAANMRGMA AAPPEVPEWK KHVIGGKKSS FGKKTDLTLV EQRQSLPIYK LRDDLIKAVT 600
  601 DNQILIVIGE TGSGKTTQIT QYLGECGFTA RGKIGCTQPR RVAAMSVAKR VAEEYGCRLG 660
  661 QEVGYTIRFE DCTSPETIIK YMTDGMLLRE CLMEAELKSY SVIMLDEAHE RTIHTDVLFG 720
  721 LLKTAVQKRP ELKLIVTSAT LDAVKFSQYF FKAPIFTIPG RTFPVEVLYT KEPETDYLDA 780
  781 SLITVMQIHL REPPGDILLF LTGQEEIDTA CEILYERMKS LGPDVPELII LPVYSALPSE 840
  841 MQTRIFDPAP AGSRKVVIAT NIAETSLTID GIFYVVDPGF VKQKVYNSKT GMDSLVVTPI 900
  901 SQAAAKQRAG RAGRTGPGKT YRLYTERAYR DEMLPTPVPE IQRTNLATTV LQLKTMGIND 960
  961 LLHFDFMDAP PVESLVMALE QLHSLSALDD EGLLTRLGRR MAEFPLEPNL SKMLIMSVAL1020
 1021 QCSDEILTIV SMLSVQNVFY RPKDKQALAD QKKAKFNQAE GDHLTLLAVY NSWKNNKFSN1080
 1081 AWCYENFVQI RTLKRSQDVR KQLLGIMDRH KLDVVSAGKN SVRIQKAICS GFFRNAAKKD1140
 1141 PQEGYRTLVD SQVVYIHPSS ALFNRQPEWV IYHELVQTTK EYMREVTTID PKWLVEFAPS1200
 1201 FFRFSDPTKL SKFKKNQRLE PLYNKYEEPN AWRISRVRRR RN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..91] deduced N/A No confident structure predictions are available.
    2 View Details [92..263] MSA 2.224996 View MSA. No confident structure predictions are available.
    3 View Details [264..560] FFAS03 2.76 Crystal structure of intact alpha subunit of aIF2 from Pyrococcus abyssi
    4 View Details [561..959] PSI-BLAST 66.522879 No description for 2hxyA was found.
    5 View Details [960..1079] deduced N/A No confident structure predictions are available.
    6 View Details [1080..1242] MSA 2.605979 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle