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View Structure Prediction Details

Protein: pea-PA
Organism: Drosophila melanogaster
Length: 1242 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pea-PA.

Description E-value Query
Range
Subject
Range
gi|28704113 - gi|28704113|gb|AAH47327.1| DHX8 protein [Homo sapiens]
925.0 [0..2] [1241..14]

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Predicted Domain #1
Region A:
Residues: [1-91]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDELQKLEYL SLVSKICTEL DNHLGINDKD LAEFIIDLEN KNRTYDTFRK ALLDNGAEFP  60
   61 DSLVQNLQRI INLMRPSRPG GASQEKTVGD K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [92-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEDKKSQLLK MFPGLALPND TYSKKEESDD DEKVKAKPEK HSETHKKTDM SDVDAAMMEL  60
   61 EALAPGEGAT LVRPHKEVSS RDRHKRRSRD RDTKRRSRSR EDRHSDRRRS RSRDKERRRR 120
  121 SRSRDNRRRS RSREDRDRDR DRRHKSSSSR DHHERRRRSR SRSTERRDRR DR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [264-560]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRDCSEKMPP PSAAMTDDPE AGKIYSGKIA NIVPFGCFVQ LFGLRKRWEG LVHISQLRAE  60
   61 GRVTDVTEVV TRNQTVKVKV MSITGQKVSL SMKEVDQDSG KDLNPLSHAP EDDESLRDRN 120
  121 PDGPFSSSTS MLNLQGNGME GDEHESRKRV TRISSPERWE IKQMISSGVL DRSEMPDFDE 180
  181 ETGLLPKDED DEADIEIEIV EEEPPFLSGH GRALHDLSPV RIVKNPDGSL AQAAMMQSAL 240
  241 SKERREQKML QREQEIEAMP TSLNKNWIDP LPEDESRSLA ANMRGMAAAP PEVPEWK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.76
Match: 1yz6A
Description: Crystal structure of intact alpha subunit of aIF2 from Pyrococcus abyssi
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [561-959]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KHVIGGKKSS FGKKTDLTLV EQRQSLPIYK LRDDLIKAVT DNQILIVIGE TGSGKTTQIT  60
   61 QYLGECGFTA RGKIGCTQPR RVAAMSVAKR VAEEYGCRLG QEVGYTIRFE DCTSPETIIK 120
  121 YMTDGMLLRE CLMEAELKSY SVIMLDEAHE RTIHTDVLFG LLKTAVQKRP ELKLIVTSAT 180
  181 LDAVKFSQYF FKAPIFTIPG RTFPVEVLYT KEPETDYLDA SLITVMQIHL REPPGDILLF 240
  241 LTGQEEIDTA CEILYERMKS LGPDVPELII LPVYSALPSE MQTRIFDPAP AGSRKVVIAT 300
  301 NIAETSLTID GIFYVVDPGF VKQKVYNSKT GMDSLVVTPI SQAAAKQRAG RAGRTGPGKT 360
  361 YRLYTERAYR DEMLPTPVPE IQRTNLATTV LQLKTMGIN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.522879
Match: 2hxyA
Description: No description for 2hxyA was found.

Predicted Domain #5
Region A:
Residues: [960-1079]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLLHFDFMDA PPVESLVMAL EQLHSLSALD DEGLLTRLGR RMAEFPLEPN LSKMLIMSVA  60
   61 LQCSDEILTI VSMLSVQNVF YRPKDKQALA DQKKAKFNQA EGDHLTLLAV YNSWKNNKFS 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1080-1242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAWCYENFVQ IRTLKRSQDV RKQLLGIMDR HKLDVVSAGK NSVRIQKAIC SGFFRNAAKK  60
   61 DPQEGYRTLV DSQVVYIHPS SALFNRQPEW VIYHELVQTT KEYMREVTTI DPKWLVEFAP 120
  121 SFFRFSDPTK LSKFKKNQRL EPLYNKYEEP NAWRISRVRR RRN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle