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Protein Overview: cbs-PA

General Information:
Name(s) found: cbs-PA / FBpp0086786 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene centrosomin's beautiful sister is referred to in FlyBase by the symbol Dmel\cbs (CG4840, FBgn0086757). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9338169..9340898. It has the cytological map location 50A9. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: centrosome cycle. 7 alleles are reported. The phenotypes of these alleles are annotated with: syncytial blastoderm embryo; centrosome; stage 5 embryo. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 611 amino acids

    Gene Ontology:
    Cellular Component: centrosome [NAS]
    perinuclear region of cytoplasm [IDA]
    cytoplasm [IDA]
    spindle [IDA]
    chromatin [IDA]
    Biological Process: centrosome cycle [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFATLKNKIK EETGDDVVQS ANQRYPGNNN NNYRLRSRRV SINSNSADDV GGGGFYNESE  60
   61 QLCELRSQCN ELTTKLSTVT QGLQQLQEEK TRVDKTNEIL LESVRVAQTQ KDIYCEEQEK 120
  121 IQNLQQIEID KLKNLLSFRE QESVDRMGLM RQQTQQIESL SEELERLRPI ESVAEDLRDE 180
  181 LEQLRHSTQQ EKNLLTTTLA AVQEENRHLK KRMKIVEESR LESLGKLNSE QQVQALIREH 240
  241 KLLEQHLEEA HLQLSDIKGS WSGQNLALET QVSRLSKQVA EETTEKRKAL KSRDDAIESR 300
  301 KQVSFELEKA KDEIKQRDDK VKLLEEEIDE LSVALKECRE ENEQQVLFER NKSQNLETEV 360
  361 KDLKTRLTAA DDRFSEYSSN AEQVAQKLRV QVTEKQEQLD ETIMQLEIER EEKMTAILRN 420
  421 AEIAQSEDIL RQQLRLERSE ASDLQERNNQ LVRDISEARQ TLQQVSSTAQ DNADKLTEFE 480
  481 RVQLEIIEKN KTIKTLNQRL IDLKKTVQKE LRSAQISTDS ESHPTTTPGH RISSSSLEAF 540
  541 STGDKGNCVI MDEVNFQYLK HVIVKFLTSR EVEARHLVRA VSTLLQLTTE EEKLLHDTLN 600
  601 WKMSWFGMKP T

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..331] PSI-BLAST 18.154902 Heavy meromyosin subfragment
    2 View Details [332..453] FFAS03 2.03 Fibrinogen C-terminal domains; Fibrinogen gamma chain
    3 View Details [454..611] PSI-BLAST 3.30103 No description for 2iw5A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.45058468282438 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.1457670954804 bayes_pls_golite062009
  • chromatin binding
    		•  1.87338136043944 bayes_pls_golite062009
  • actin binding
    		•  1.48871115327078 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.38505016881116 bayes_pls_golite062009
  • DNA binding
    		•  1.29464499177454 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.27419374347122 bayes_pls_golite062009
  • protein binding
    		•  1.03780839342631 bayes_pls_golite062009
  • transcription factor activity
    		•  0.694399096428821 bayes_pls_golite062009
  • histone binding
    		•  0.508815747007202 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.45737598186064 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.41388714312156 bayes_pls_golite062009
  • actin filament binding
    		•  0.26311995282891 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle