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Protein Overview: vg-PA

General Information:
Name(s) found: vg-PA / FBpp0086898 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • The gene vestigial is referred to in FlyBase by the symbol Dmel\vg (CG3830, FBgn0003975). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8771794..8786900. It has the cytological map location 49E1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: transcription regulator activity. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; system development; organ morphogenesis; regulation of biological process; regionalization; regulation of cellular process; regulation of cell cycle; leg morphogenesis; regulation of cell proliferation; sensory organ development; muscle organ development. 417 alleles are reported. The phenotypes of these alleles are annotated with 55 unique terms, many of which group under: adult segment; adult mesothoracic segment; organ system; peripheral nervous system; appendage segment; external compound sense organ; antennal segment; abdominal oblique muscle; dorsal thoracic disc; indirect flight muscle. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 453 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA][NAS]
    Biological Process: wing disc development [IGI][IMP]
    imaginal disc-derived leg morphogenesis [IMP]
    wing disc morphogenesis [IMP]
    dorsal/ventral lineage restriction, imaginal disc [IMP]
    wing disc proximal/distal pattern formation [IMP]
    haltere development [IMP]
    imaginal disc-derived wing morphogenesis [NAS][TAS]
    imaginal disc-derived wing margin morphogenesis [NAS]
    regulation of transcription [IEA]
    somatic muscle development [IMP]
    regulation of mitotic cell cycle [IMP]
    regulation of cell proliferation [IMP]
    compound eye morphogenesis [IMP]
    wing disc dorsal/ventral pattern formation [IMP]
    Molecular Function: transcription regulator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVSCPEVMY GAYYPYLYGR AGTSRSFYQY ERFNQDLYSS SGVNLAASSS ASGSSHSPCS  60
   61 PILPPSVSAN AAAAVAAAAH NSAAAAVAVA ANQASSSGGI GGGGLGGLGG LGGGPASGLL 120
  121 GSNVVPGSSS VGSVGLGMSP VLSGAAGHSL HSSHRTHAHS LAHAHTHPHS HTHTHTHQTK 180
  181 EEDLIVPRSE AEARLVGSQQ HQHHNESSCS SGPDSPRHAH SHSHPLHGGG GATGGPSSAG 240
  241 GTGSGGGDGG GTGAIPKNLP ALETPMGSGG GGLAGSGQGQ AQYLSASCVV FTNYSGDTAS 300
  301 QVDEHFSRAL NYNNKDSKES SSPMSNRNFP PSFWNSNYVH PIPAPTHHQV SDLYGTATDT 360
  361 GYATDPWVPH AAHYGSYAHA AHAHAAHAHA YHHNMAQYGS LLRLPQQYAS HGSRLHHDQQ 420
  421 TAHALEYSSY PTMAGLEAQV AQVQESSKDL YWF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] deduced N/A No confident structure predictions are available.
    2 View Details [106..277] PSI-BLAST 4.69897 RBP1
    3 View Details [278..453] MSA 9.145994 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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