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Protein Overview: CG33671-PA, FBpp...

General Information:
Name(s) found: FBpp0305315 [FlyBase]
CG33671-PA / FBpp0086997 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=2R:complement(8521759..8522931); ID=FBpp0305315; name=CG33671-PB; parent=FBgn0061359,FBtr0333102; dbxref=REFSEQ:NP_001260922,GB_protein:AGB93455,FlyBase:FBpp0305315,FlyBase_Annotation_IDs:CG33671-PB; MD5=37c08782c0fe0fb9416a8e7c7c379e51; length=390; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG33671 (CG33671, FBgn0061359). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8521668..8523666. It has the cytological map location 49B10. Based on sequence similarity, it is predicted to have molecular function</span>: mevalonate kinase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: isoprenoid biosynthetic process; phosphorylation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 390 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: phosphorylation [ISS]
    isoprenoid biosynthetic process [ISS]
    Molecular Function: ATP binding [IEA]
    mevalonate kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKFQVHSPG KVILHGEHAV VYHRPALAAV VGLGTTLRFR QLEDSQVASF QLEALNCTLE  60
   61 IQLPEFNGFL AEFRSKYPSD STANLLEAVR AEVSKQLERS GGNAPKQHTQ RAFISIYYLL 120
  121 AGAVLSAPGD KKLTLQTGFQ VQVDSQLTVG AGLGSSASFG AALATTFLIL AGHFDRDSYL 180
  181 SEANQALISS WAYESERVNH GTPSGLDNTV CTYGGMLRYV KGQGFQSLKI QKPLNILLVD 240
  241 SRVSRSTADI VAKVRHLGDA FPQLIEAIWQ ACEELVAAAV PLYESFGNAQ DDSSKFEQLE 300
  301 RLFQINNDLL KAIGVSHPKL EQIFTIAFKR GFFSKLTGAG AGGYVIVLLP ENYECNEVYW 360
  361 KLKEELESAG FGVHVTTAGG EGLRVSSLDD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..390] PSI-BLAST 48.69897 Mevalonate kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.57444343595083 bayes_pls_golite062009
  • kinase activity
    		•  2.45533953107206 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.31269308415192 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.15678581504347 bayes_pls_golite062009
  • structural molecule activity
    		•  1.96296069933386 bayes_pls_golite062009
  • binding
    		•  1.9197744309809 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.90728659801871 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.75408506104351 bayes_pls_golite062009
  • DNA binding
    		•  1.50208874269692 bayes_pls_golite062009
  • transferase activity
    		•  1.44847475955289 bayes_pls_golite062009
  • catalytic activity
    		•  0.836142537655721 bayes_pls_golite062009
  • diphosphomevalonate decarboxylase activity
    		•  0.714132174817049 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.49664490095304 bayes_pls_golite062009
  • mRNA binding
    		•  0.396503273803591 bayes_pls_golite062009
  • protein binding
    		•  0.191135371876197 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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