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Protein Overview: psq-PB, psq-PC

General Information:
Name(s) found: psq-PC / FBpp0089330 [FlyBase]
psq-PB / FBpp0087368 [FlyBase]
Description(s) found:
Found 34 descriptions.
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  • The gene pipsqueak is referred to in FlyBase by the symbol Dmel\psq (CG2368, FBgn0004399). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6445409..6503753. It has the cytological map location 47A13-47B1. It is reported to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: olfactory behavior; imaginal disc-derived wing morphogenesis. 79 alleles are reported. The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: embryonic abdomen; embryonic segment; organ system; embryonic tagma; peripheral nervous system; female germline cyst; external compound sense organ; adult segment; nervous system; adult mesothoracic segment. It has 12 annotated transcripts and 12 annotated polypeptides. [FlyBase]
  • The gene pipsqueak is referred to in FlyBase by the symbol Dmel\psq (CG2368, FBgn0004399). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6445409..6503753. It has the cytological map location 47A13-47B1. It is reported to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: olfactory behavior; imaginal disc-derived wing morphogenesis. 79 alleles are reported. The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: embryonic abdomen; embryonic segment; organ system; embryonic tagma; peripheral nervous system; female germline cyst; external compound sense organ; adult segment; nervous system; adult mesothoracic segment. It has 12 annotated transcripts and 12 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1064 amino acids

    Gene Ontology:
    Cellular Component: nucleus [TAS]
    Biological Process: gene silencing [TAS]
    imaginal disc-derived wing morphogenesis [IMP]
    pole plasm assembly [NAS]
    olfactory behavior [IMP]
    Molecular Function: DNA binding [IEA][NAS][TAS]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAVRGHQYF SLRWNNYQNT MTSVFQQLRE DLSFVDVTLS CEHGSLKAHK VVLSACSTYF  60
   61 QKLLLENPCK HPTIILPADI IFTDLKTIID FVYRGEIDVT ESELQGLLRT AEQLKIKGLC 120
  121 ETAENADDLN DAATATITVS ENIQQAVVGN IVNAAIVPGA PSPSLEQQQQ HHQQQQQQQA 180
  181 QEQHQQQQVH AQQQQQQQQQ INAALLTQHG VSSGSVSLSG QLLSSSASGS SGSLAGGQQA 240
  241 SQTPSGLQPT PRKSRLKRSK SPDLSSGGGA GSSGGSSSGS TQQQPQPAHH HHPQTILIQG 300
  301 QNPNSIVSLQ QTADGNYIPV SGSGDDSDAE DHEHEHNHGH GHGHGGHTHG HGHSHEHSHD 360
  361 HEHEHKPNKI CKTEHSVASP ASNSSSASNN AAGVSGVTST GQAIVTQIVV ARDGKDTKNM 420
  421 TSLGMGMNGG LLGVPMGFLD FTPEPPAPSA TPVTVTEHVD LSCNPSTDTR DLSNTTEPLD 480
  481 IDNHLAQQIH RLDQSPMHSI SHHHTGDESN SNLVQHIKSE VIEAKHLAAQ HHALSQAQQQ 540
  541 HAHHQAHQQH QQHQQQQHQQ QQQHLHAQQL LAQSQLQQQQ QQQQQQQQHH QQQQQQAAAA 600
  601 AAAAGVHGQH GGHVTHADIG GATVMEIDPS QIKHEPGMII TPEIVNMMSS GHMDMYNSDT 660
  661 SEDSMMIANG SPHDQKEPHY TNLDQQHGLG GSVCGPGPGG AGGGGGMSGG AGSGSGEKGQ 720
  721 FNGPKAWTQD DMNSALDALK NQNMSLTKAS AIYGIPSTTL WQRAHRMGIE TPKKEGGTKS 780
  781 WNEDALQNAL EALRSGQISA NKASKAFGIP SSTLYKIARR EGIRLAAPFN AAPTTWTPED 840
  841 LERALEAIRA GNTSVQKASA EFGIPTGTLY GRCKREGIEL SRSNPTPWSE DAMNEALNSV 900
  901 RVGQMSINQA AIHYNLPYSS LYGRFKRGKY DVVANTSGVA LLNTSGNTTG SIEIIEHSQE 960
  961 NSLHMLQQQF PYSPSPHPPT PQHHSTPQHH SSAQQGPPTP QHMQQHVVHM QQQQQQQQQQ1020
 1021 SPHPGHHPQH MQQDVVTSSS QVVHSQQQQQ LQQIYQHHGT PERS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..124] PSI-BLAST 14.0 No description for 2nn2A was found.
    2 View Details [125..272] deduced N/A No confident structure predictions are available.
    3 View Details [273..381] PSI-BLAST 13.30103 No description for 2dlqA was found.
    4 View Details [382..441] FFAS03 1.24 No description for 2qfiA was found.
    5 View Details [442..608] PSI-BLAST 12.69897 Five-finger GLI1
    6 View Details [609..714] deduced N/A No confident structure predictions are available.
    7 View Details [715..833] MSA 1.006979 View MSA. No confident structure predictions are available.
    8 View Details [834..1064] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription activator activity
    		•  3.52873291636993 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.27542149084008 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22082323675675 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.53101891154822 bayes_pls_golite062009
  • chromatin binding
    		•  2.18464662431232 bayes_pls_golite062009
  • protein binding
    		•  2.05530362750351 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.63161912031789 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.34049786451995 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
    4 No functions predicted.
    5
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription activator activity
    		•  3.52873291636993 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.27542149084008 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22082323675675 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.53101891154822 bayes_pls_golite062009
  • chromatin binding
    		•  2.18464662431232 bayes_pls_golite062009
  • protein binding
    		•  2.05530362750351 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.63161912031789 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.34049786451995 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle